Sulfadoxine
General information:
| Withdrawn ID: | 521 |
|---|---|
| Canonical SMILES: | |
| Standard InChI: | |
| Standard InChIKey: | |
| ATC class(es): | J01EQ13 |
| Molecular Formula: | C12H14N4O4S |
| Molweight: | 310.329 |
Withdrawal information:
| Withdrawn due to drug safety reasons: | No |
|---|---|
| First approved: | 1981 |
Side-effects:
| Total reported cases (submitted by medical professionals) with Sulfadoxine as primary suspect: | 174 |
|---|
Reported final outcomes:
| Hospitalization (initial or prolonged): | 7 |
|---|---|
| Death: | 4 |
| Life-Threatening condition: | 3 |
| Congenital anomaly: | 2 |
Reported side-effects:
| Side-effect | Case number |
|---|---|
| LEUKOPENIA | 2 |
| CONVULSION | 2 |
| CONGENITAL TOXOPLASMOSIS | 2 |
| CHOLESTASIS | 1 |
| FOLATE DEFICIENCY | 1 |
| EYE INFECTION TOXOPLASMAL | 1 |
| ERYTHEMA MULTIFORME | 1 |
| DRUG RESISTANCE | 1 |
| DRUG EXPOSURE DURING PREGNANCY | 1 |
| DIZZINESS | 1 |
| Death | 1 |
| COMA | 1 |
| HAEMOLYTIC ANAEMIA | 1 |
| CEREBRAL VENTRICLE DILATATION | 1 |
| CEREBRAL CALCIFICATION | 1 |
| BRAIN MALFORMATION | 1 |
| BLOOD CREATININE INCREASED | 1 |
| BLINDNESS CORTICAL | 1 |
| ASCITES | 1 |
| APNOEA | 1 |
| AGRANULOCYTOSIS | 1 |
| ACUTE HEPATIC FAILURE | 1 |
| ABORTION MISSED | 1 |
| PANCYTOPENIA | 1 |
| VITAMIN B12 DEFICIENCY | 1 |
| UVEITIS | 1 |
| TRANSAMINASES INCREASED | 1 |
| TOXOPLASMOSIS | 1 |
| SUICIDE ATTEMPT | 1 |
| RENAL FAILURE ACUTE | 1 |
| RASH PAPULAR | 1 |
| RASH ERYTHEMATOUS | 1 |
| PROSTATOMEGALY | 1 |
| PNEUMOCYSTIS JIROVECI PNEUMONIA | 1 |
| VOMITING | 1 |
| OVERDOSE | 1 |
| NEUTROPENIA | 1 |
| MENINGITIS | 1 |
| INTERSTITIAL LUNG DISEASE | 1 |
| HYPOGLYCAEMIC COMA | 1 |
| HYDROCEPHALUS | 1 |
| HEPATOSPLENOMEGALY | 1 |
| HEPATITIS ACUTE | 1 |
| HEADACHE | 1 |
Toxicity information:
| Toxicity class: | 5 |
|---|---|
| Toxicity type: | N/A |
| LD50: | 4680 mg/kg |
External links:
| ChEBML: | CHEMBL1539 |
|---|---|
| DrugBank: | DB01299 |