Enzyme - Results


Conjugation: MET



Information Structure
Name MET
Synonyms
Methyltransferase
UniProt ID tpmt_human
Accession Number O14806
O15423
O15424
O15425
O15426
O15515
O15548
O43213
P51580
Q5VUK6
Q9UBE6
Q9UBT8
Q9UE62
PDB ID 2BZG
2H11
EC Number2.1.1.67
Drug Interactions
NameRelationReferences
AcetylcholinInducer 9456
Acetylsalicylic AcidInhibitor 6633508
AdemetionineSubstrate 19651420,
3370823,
7998928,
19796640,
14738970,
7897657,
10805450,
10785817,
6721499
AngiotensinamideInducer 1071652
ArgatrobanInducer 12361198
Ascorbic Acid (vit C)Inhibitor,Substrate 6344591,
9054258
AzacitidineInhibitor 21624006,
20004793,
20010512,
16341236,
22399596,
19589026
AzathioprineSubstrate 16855176,
10208641,
8171183,
15776134,
7570968,
11600469,
11093885,
15792824,
15188821,
7857117,
9841604,
20136357,
18093457,
20726808,
10798786,
15476481,
19223932,
15354273,
15316356,
17654066,
11012112,
8582469,
9931345,
14651577,
11488818,
11134264,
14556746
BendroflumethiazideInhibitor 8866635,
8866635
CaptoprilSubstrate 6344869,
1788978
ChlorhexidineInhibitor 3337739
ChloroquineInhibitor 3337739,
7875186
ChlorphenamineInducer 11759112
CocaineInducer 9231750
DeanolSubstrate 3663398,
6366796
DecitabineInhibitor 21455989,
17925555,
20384584,
15270655,
16357155,
18790780,
20932295,
21153863,
21408221,
18425818,
17023173,
17313156,
15131354,
16341238
DicycloverineInhibitor 3789890
DiosminInhibitor 3789890
EntacaponeInhibitor,Inducer 12393055,
21095464,
21164341,
12403054,
11793162,
21280081,
18290846,
15372589,
20077469,
8035933,
9399218,
16437585,
9597116,
9085195,
19936145,
21533995,
11160877,
9633684,
9591516,
16485914,
19909787,
18074122,
17705259,
19715385,
16604302,
11147507,
21209248,
21255197,
20220040,
EpinephrineInducer,Substrate 6859813,
6602045,
6603348
EstradiolInducer,Substrate 8055052
Folic AcidInhibitor 15878587,
19618311,
17565222
FosfocreatineInhibitor 22123819
GlucagonInducer 6251072,
2994664,
6251072,
6251072
HistamineSubstrate 17562176,
18266724,
3159351,
19538200,
8978720,
8780048,
14667820,
7616240,
2849794,
8448680,
16648665,
9547362,
18154359,
18086566,
11880199,
10858271,
10051705,
15551002,
10712622,
16168438,
7943261,
12358773,
10803682,
1530666,
12417108,
7822670,
15693910
HydralazineInducer 3710285
HydrocortisoneInhibitor 571728
ImipramineInhibitor 6686446,
6686446
IsoprenalineSubstrate 3678363,
2865990,
21371608,
367478,
11882582
KetoprofenInhibitor 17553913
KetotifenInducer 1711282
LevodopaSubstrate 8190296,
9333106,
8112370,
16772808,
11147507,
15390046,
10882160,
16340382,
19676096,
15779086,
18289028,
7737328,
7957769,
12075857,
14673217,
11693181,
9682265
LidocainInhibitor 7716464
MepacrineInhibitor 3832018,
11566133,
3337739,
12713826,
9062867
MercaptopurineSubstrate 8453958,
20130603,
15354273,
16431300,
9565678,
10875470,
9450506
MesalazineInhibitor 7640156,
9780130
MethotrexateSubstrate,Inducer 16438485
Methyldopa (levorotatory)Substrate,Inhibitor 6714437,
21371608,
11058906
MoclobemideInhibitor 8612391
NaproxenInhibitor 17553913
OlsalazineInhibitor 9357398
PargylineInhibitor,Inducer 8717160,
8147263,
3967097,
1762989,
8878060,
6472500,
1628144
PhysostigmineInhibitor 8978720,
1886293
PlicamycinInhibitor 17893516
ProcaineInhibitor 18345608,
16510601,
18078446
ProgesteroneInducer,Inhibitor 8055052,
2033240
Pyridoxine (vit B6)Inhibitor 3004168
RibavirinInhibitor 15152003
Selenium CompoundsInhibitor 9600343
TacrineInhibitor 8978720,
1530666,
2403387,
1886293,
15834447
TamoxifenSubstrate 15288375
TemozolomideInhibitor 2706009
TioguanineSubstrate,Inducer 12135816,
10751626,
10764140,
15167635,
16175140,
19535798,
9931345,
21086934,
11479220,
10213363,
8873214,
15897017,
657528,
14556746,
20521035,
11179762,
10954350,
16476125,
17036413,
10424321,
13679074,
15060506
TolcaponeInhibitor 20394182,
10448949,
10565698,
10510160,
11942697,
9339691,
9591523,
9252801,
9754991,
9333106,
9591224,
12538800,
15784340,
7768276,
10882160,
8879148,
7566641,
12573869,
18536698,
9305320,
9918342,
8527287,
9591521,
9808337,
12111468,
9708959,
19783845,
17909307,
11290879,
19503773,
TrimethoprimInducer 15737567
TubocurarineInhibitor 4083176
UbidecarenoneSubstrate 10760477,
10419476
VareniclineInhibitor 21368748
VecuroniumInhibitor 2898903
VirginiamycinInhibitor 18094627
VorinostatInhibitor 21678477