Enzyme - Results


CYP: 2A6



Information Structure
Name 2A6
Synonyms
Coumarin 7-hydroxylase
UniProt ID cp2a6_human
Accession Number A7YAE5
B2R7F6
P00190
P10890
P11509
Q16803
Q4VAT9
Q4VAU0
Q4VAU1
Q9H1Z7
Q9UCU0
Q9UK48
PDB ID 1Z10
1Z11
2FDU
2FDV
2FDW
2FDY
3EBS
EC Number1.14.14.1
Drug Interactions
NameRelationReferences
AmfetamineInhibitor 12746108,
AmlodipineInhibitor Umm
AmobarbitalInducer Umm
ArtemisininSubstrate 10583023,
10583023,
ArtesunateSubstrate 12920490,
AzelastineInhibitor 10383922,
AzithromycinInhibitor 11978200,
BuprenorphineInhibitor Umm
BupropionSubstrate Umm
CarbamazepineInducer 20719908
ChloroformSubstrate 11996015,
ChloroxylenolSubstrate 11996015,
ChlorzoxazoneSubstrate Umm
10534312,
CinnarizinSubstrate 8951176,
CisaprideSubstrate Umm
10780971,
ClofibrateInhibitor Umm
11038160,
ClomethiazoleSubstrate 11996015,
ClomifeneInhibitor 9054622
ClotrimazoleInducer,Inhibitor 1472091
ClozapineSubstrate Umm
CocaineInducer 7654131
CyclophosphamideSubstrate Umm
10348794,
DesipramineInhibitor Umm
DexfenfluramineInhibitor 9825834,
DexmedetomidineSubstrate Umm
Diethyl EtherSubstrate 9101044
DiethyltoluamideSubstrate 11854147,
DisulfiramInhibitor,Substrate Umm
DronabinolSubstrate 1103455,
EletriptanInducer 10611140,
EntacaponeInhibitor Umm
FlunarizineSubstrate 8951176,
FlunitrazepamSubstrate 11159802,
10574680,
FluorouracilSubstrate 11095583
FomepizoleInhibitor 9143352,
FormoterolSubstrate Drugbank
HalothaneSubstrate Umm
11506127,
8886607,
HistamineInhibitor 17237153
IfosfamideSubstrate Umm
12136253,
Indigo CarmineInhibitor 16009655
IsoniazidInhibitor Umm
11868802,
15528841,
IsopropanolInhibitor 9492382,
9929510,
10611138,
11996015,
KetoconazoleInhibitor Umm
9143352,
11978200,
LetrozoleSubstrate,Inhibitor Umm
LevoverbenoneSubstrate 12867494
LidocainSubstrate Umm
8866826,
11996015,
MedifoxamineSubstrate 11996015,
MemantineInhibitor 15378224,
15378224,
MenadioneInhibitor 11996015,
MethoxsalenSubstrate,Inhibitor 10583023,
9665710,
MethoxyfluraneSubstrate 7879937,
MetyraponeInhibitor 3978021,
8863822,
9143352,
MiconazoleInhibitor 9143352,
NicotineInhibitor,Substrate 14757175,
9143352,
Nicotinyl Alcohol (pyridylcarbinol)Substrate 18559554
NilvadipineInhibitor 14993813,
NorfloxacinInhibitor 14738594
Orphenadrine (citrate)Inhibitor 9172960,
9172960,
ParacetamolSubstrate Umm
9548799,
8374050,
PerazineSubstrate 15056479,
PhenacetinSubstrate 9825829,
10548449,
PhenazoneSubstrate 8801065,
PhenobarbitalInducer,Inhibitor 15448115,
11978200,
12642468,
11038160,
PilocarpineInhibitor,Substrate 11978200,
8590980,
PrednisoloneInhibitor 11978200,
ProgesteroneSubstrate Umm
9667077,
11996015,
PropofolSubstrate Umm
9771309,
RifampicinInducer,Inhibitor,Substrate Umm
12642468,
12584154,
RosiglitazoneInhibitor 12642470
RoxatidineSubstrate 11556126
SelegilineSubstrate Umm
SeratrodastInhibitor 9010637,
SevofluraneSubstrate Umm
7879937,
SulconazoleInhibitor Umm
SulfaphenazoleInhibitor 11978200,
TamoxifenSubstrate Umm
8293548,
TegafurSubstrate 11095583,
11106261,
16897985,
11095583,
11106261,
12042667,
ThalidomideSubstrate 10711629
ThiamazoleInhibitor 9172960,
11996015,
TranylcypromineInhibitor 9143352,
11181487,
11353760,
9143352,
TretinoinSubstrate Umm
TroleandomycinInhibitor 11978200,
TrospiumInhibitor 10628907
Valproic AcidSubstrate 15795555,
15795555,
ZidovudineSubstrate Source: Www.umm.edu,
8053924,
11996015,