Compound - Results

Gefitinib

Java required.


Information Structure
Name Gefitinib
Synonyms
184475-35-2
4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline
4-quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-
4-quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-4-morpholin)propoxy)-
4-quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-
6-(3-morpholinopropoxy)-n-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-amine
ac-1556
ac1l3x0a
akos000280752
bcb03_000781
bio-0046
c419708
ccris 9011
chebi:188232
chebi:49668
chembl939
cid123631
cu-00000000396-1
d01977
db00317
db07998
ec-000.2409
en002708
ft-0081035
gefitini; Iressa
Gefitinib
gefitinib (jan/usan/inn)
gefitinib [usan]
gefitinib, Iressa, Zd1839
hms2089b19
i01-1227
ire
iressa
iressa (tn)
iressa(tm)
Irressat
k00240
kbioss_002241
kinome_3321
kinome_3322
ls-139916
n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
n-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamide
n-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
n-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
n-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine
ncgc00159455-02
ncgc00159455-03
nchembio.117-comp18
nchembio866-comp14
nsc715055
s1025_selleck
stk621310
tarceva
unii-s65743jhbs
ZD 1839
zd-1839
zd-1839, Iressa, Gefitinib
ZD1839
zinc19632614
ATC L01XX31
L01XE02
CID 123631
CAS 184475352
Drugbank ID DB00317
TTD Drug ID DAP000657
SMILES COC1=CC2=NC=NC(NC3=CC=C(F)C(Cl)=C3)=C2C=C1OCCCN4CCOCC4
Formula C22H24ClFN4O3
Molweight 446.902
Atoms 31
LogP 4.2865
Rotatable Bonds 8
H-Bond Donors 0
H-Bond Acceptors 8
CYP interactions
NameRelationsReferences
2C19Inhibitor umm
2D6Substrate Inhibitor 16719544
umm
15788367
16176119
3A4Substrate 15788367
17575239
16123050
15499696
16176119
15788367
14977817
16123050
Transporter
AC-No.NameReferences
Q9UNQ0Mitoxantrone resistance-associated protein20421331
Extrarenal fraction 0.9
Elimination half-life 41.0h