Compound - Results

Celecoxib

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Information Structure
Name Celecoxib
Synonyms
4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
Celebra
Celebrex
Celecoxib
HSDB 7038
p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
SC 58635
YM 177
YM177
ATC M01AH01
CID 2662
CAS 169590425
Drugbank ID DB00482
TTD Drug ID DAP000737
SMILES CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(N)(=O)=O)C(F)(F)F
Formula C17H14F3N3O2S
Molweight 381.372
Atoms 26
LogP 5.295
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 7
CYP interactions
NameRelationsReferences
2C9Substrate 12392591
15058617
10749518
10773015
11337938
2D6Inhibitor 169590425
12891223
3A4Substrate 10773015
10773015
Phase2 interactions
NameReferences
SUL 16011896,
17239972
Extrarenal fraction 0.7
Elimination half-life 13.0h