Compound - Results

Nevirapine

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Information Structure
Name Nevirapine
Synonyms
11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2,3-e)(1,4)diazepin-6-one
BIRG 0587
DRG-0116
Nevirapine
Viramune
ATC J05AG01
CID 4463
CAS 129618402
Drugbank ID DB00238
TTD Drug ID DAP000184
SMILES CC1=CC=NC2=C1NC(=O)C3=C(N=CC=C3)N2[C@H]4CC4
Formula C15H14N4O
Molweight 266.298
Atoms 20
LogP 2.4783
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
1A2Inhibitor 11225565
2B6Substrate Inducer 14628297
15864119
17003847
10570031
15864119
14628297
2C9Substrate Inhibitor 10570031
11996015
11225565
2D6Substrate Inhibitor 10570031
11225565
3A4Substrate Inhibitor Inducer 12405866
11475806
10082072
10570031
10570031
10082072
11996015
Extrarenal fraction 0.95
Elimination half-life 28h