Compound - Results

Fluconazole

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Information Structure
Name Fluconazole
Synonyms
2,4-Difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl Alcohol
2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)-2-propanol
Afungil
Alflucoz
alpha-(2,4-Difluorophenyl)-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol
Baten
Biocanol
Biozolene
Canzol
CCRIS 7211
Cryptal
Diflucan
Dimycon
DRG-0005
Elazor
Flucazol
Fluconazol
Fluconazole
Fluconazolum
Flukezol
Flunizol
Fluzone
Forcan
Fungata
Mutum
Oxifugol
Pritenzol
Syscan
Triflucan
UK 49858
Zemyc
Zonal
ATC D01AC15
J02AC01
CID 3365
CAS 086386734
Drugbank ID DB00196
TTD Drug ID DAP000628
SMILES OC(CN1C=NC=N1)(CN2C=NC=N2)C3=C(F)C=C(F)C=C3
Formula C13H12F2N6O
Molweight 306.271
Atoms 22
LogP 0.7358
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 7
CYP interactions
NameRelationsReferences
1A1Inducer 17283379
1A2Inhibitor umm
2C8Inhibitor umm
2C9Substrate Inhibitor 14747429
9551703
umm
10799653
10709776
11475469
10952477
2C18Inhibitor 15963096
2C19Inhibitor 10709776
11475469
10709776
umm
2D6Inhibitor 16984215
3A4Inhibitor Inducer umm
15692832
11475469
16406388
3A5Inhibitor Inducer 16406388
16172184
16822276
18220561
19889796
8520811
11B1Inhibitor 7663533
19AInhibitor 7709362
Phase2 interactions
NameReferences
UGT 20484152
Extrarenal fraction 0.2
Elimination half-life 30h