Compound - Results

Rifampicin

Java required.


Information Structure
Name Rifampicin
Synonyms
3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
3-(4-Methylpiperazinyliminomethyl)-rifamycin SV
5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-(N-(4-methyl-1-piperazinyl)formimidoyl)-2,7-(epoxypentadeca(1,11,13)trienimino)
8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
8-(4-Methylpiperazinyliminomethyl) Rifamycin SV
Archidyn
Arficin
Arzide
Ba 41166/E
Benemicin
CCRIS 551
Dione 21-acetate
Doloresum
DRG-0109
EINECS 236-312-0
Eremfat
Fenampicin
HSDB 3181
L-5103 Lepetit
NSC 113926
R/AMP
RAMP
Rifa
Rifadin
Rifadin I.V.
Rifagen
Rifaldazin
Rifaldazine
Rifam
Rifamor
Rifampicin
Rifampicin SV
Rifampicina
Rifampicine
Rifampicinum
Rifampin
Rifamycin AMP
Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-
Rifaprodin
Rifcin
Rifinah
Rifobac
Rifoldin
Rifoldine
Rifomycin Sv, 8-(N-(4-Methyl-1-piperazinyl)formidoyl)-
Riforal
Rimactan
Rimactane
Rimactazid
Rimactizid
Rimazid
Sinerdol
Tubocin
ATC J04AB02
CID 5381226
CAS 013292461
TTD Drug ID DAP000197
SMILES CO[C@H]1C=CO[C@@]2(C)OC3=C(C2=O)C4=C(O)C(C=NN5CCN(C)CC5)=C(NC(=O)C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)C(O)=C4C(O)=C3C
Formula C43H58N4O12
Molweight 822.94
Atoms 73
LogP 4.0217
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 16
CYP interactions
NameRelationsReferences
1A1Inducer 10643869
15057403
18559486
8819303
9972473
1A2Substrate Inducer 12642468
10591535
16758262
1B1Inducer 9972473
2A6Substrate Inhibitor Inducer umm
11978200
12642468
12584154
2A13Inducer 20035023
9972473
2B6Substrate Inducer umm
15548381
12584154
16815319
2C8Substrate Inhibitor Inducer umm
16176562
11368292
15001966
9402947
15371985
15676042
12642468
15676042
2C9Substrate Inducer 14600250
9010637 15676042
11136298
umm
11368292
15001966
9157990
14534520
15676042
12642468
14722322
2C18Inducer 11257517
12130704
12882588
19702536
20035023
20086032
9972473
2C19Substrate Inducer 12584154
11735605
12426514
9489590
11735605
2D6Substrate Inducer 15001973
19601803
20035023
8049635
9972473
10591535
2E1Substrate Inducer 12642468
8786635
2F1Inducer 20035023
9972473
3A4Substrate Inhibitor Inducer umm
10729196
15855724
15769886
16176119
15554232
15548381
14581727
15676042
12584154
16176562
20124517
11735605
3A5Substrate Inhibitor Inducer 10729196
12673034
15252010
20124517
15550722
18799805
3A7Inducer 12673034
3A43Inducer 11266076
4A11Inducer 12584154
7A1Inhibitor 15331348
Transporter
AC-No.NameReferences
A5D8U6ABCA1 protein 17088262
O15245Solute carrier family 22 member 121270793
P08183P-glycoprotein 118238892
P45844ATP-binding cassette sub-family G member 1 12040753
P46721Sodium-independent organic anion transporter21605667
Q14973Sodium/bile acid cotransporter10869292
Q92887Canalicular multispecific organic anion transporter 116513445
Q9NPD5Solute carrier family 21 member 816129589
Q9Y6L6Solute carrier organic anion transporter family member 1B121430235
Extrarenal fraction 0.96
Elimination half-life 3.3h