Compound - Results

Pyrimethamine

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Information Structure
Name Pyrimethamine
Synonyms
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
2,4-Pyrimidinediamine, 5-(p-chlorophenyl)-6-ethyl-
4753 R.P.
5-(4-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
5-25-12-00255 (Beilstein Handbook Reference)
AI3-25005
BRN 0219864
BW 50-63
CCRIS 546
Chloridin
Chloridine
Chloridyn
Darachlor
Daraprim
Diaminopyritamin
DRG-0027
EINECS 200-364-2
Erbaprelina
Ethylpyrimidine
Khloridin
Malocid
Malocide
NCI-C01683
NSC 3061
Pirimecidan
Pirimetamin
Pirimetamina
Pyrimethamine
Pyrimethaminum
RP 4753
Tindurin
WR 2978
ATC P01BD01
CID 4993
CAS 000058140
Drugbank ID DB00205
TTD Drug ID DAP001493
SMILES CCC1=C(C(N)=NC(N)=N1)C2=CC=C(Cl)C=C2
Formula C12H13ClN4
Molweight 248.711
Atoms 17
LogP 3.6862
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
2C8Inhibitor umm
2C9Inhibitor umm
2D6Inhibitor umm
Phase2 interactions
NameReferences
GST 11807801
Extrarenal fraction 1
Elimination half-life 82h