Compound - Results

Spironolactone

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Information Structure
Name Spironolactone
Synonyms
17-Hydroxy-7alpha-mercapto-3-oxo-17alpha-pregn-4-ene-21-carboxylic Acid, Gamma-lactone Acetate
17alpha-Pregn-4-ene-21-carboxylic Acid, 17-hydroxy-7alpha-mercapto-3-oxo-, Gamma-lactone, Acetate
3-(3-Keto-7-alpha-acetylthio-17-beta-hydroxy-4-androsten-17-alpha-yl)propionic Acid Lactone
3-(3-Oxo-7-alpha-acetylthio-17-beta-hydroxyandrost-4-en-17-beta-yl)propionic Acid Lactone
4-18-00-01601 (Beilstein Handbook Reference)
7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
Acelat
Aldactone
Aldactone A
Alderon
BRN 0057767
Dira
EINECS 200-133-6
Espironolactona
Euteberol
HSDB 3184
Melarcon
NSC 150399
Pregn-4-ene-21-carboxylic Acid, 7-(acetylthio)-17-hydroxy-3-oxo-, Gamma-lactone, (7alpha,17alpha)-
SC 15983
SC 9420
Spiresis
Spiridon
Spiro(17H-cyclopenta(a)phenauthrene-17,2-(3H)-furan)
Spiro-Tablinen
Spiroctan
Spirolactone
Spirolang
Spirone
Spironocompren
Spironolactone
Spironolactone A
Spironolactonum
Spironolattone
Uractone
Urusonin
Verospiron
Verospirone
Xenalon
ATC C03DA01
CID 5267
CAS 000052017
SMILES CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]45CCC(=O)O5)[C@H]13
Formula C24H32O4S
Molweight 416.573
Atoms 29
LogP 4.8523
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
2C8Inhibitor 15601807
3A4Inducer 12011477
3A5Inducer 12011477
11B1Inhibitor Inducer 7663533
11996015
Phase2 interactions
NameReferences
UGT 3120728,
2127732
Extrarenal fraction 1.0
Elimination half-life 1.3h