Compound - Results

Propylthiouracil

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Information Structure
Name Propylthiouracil
Synonyms
2,3-Dihydro-6-propyl-2-thioxo-4(1H)-pyrimidinone
2-Mercapto-4-hydroxy-6-n-propylpyrimidine
2-Mercapto-6-propyl-4-pyrimidone
2-Thio-4-oxo-6-propyl-1,3-pyrimidine
2-Thio-6-propyl-1,3-pyrimidin-4-one
4(1H)-Pyrimidinone, 2,3-dihydro-6-propyl-2-thioxo-
4-Propyl-2-thiouracil
6-N-Propyl-2-thiouracil
6-N-Propylthiouracil
6-Propil-tiouracile
6-Propyl-2-thio-2,4(1H,3H)pyrimidinedione
6-Propyl-2-thiouracil
6-Propylthiouracil
6-Thio-4-propyluracil
AI3-25477
CCRIS 544
EINECS 200-103-2
HSDB 3390
NSC 6498
Procasil
Propacil
Propilthiouracil
Propiltiouracile
Propiltiouracilo
Propycil
Propyl-thiorist
Propyl-thiorit
Propyl-thyracil
Propylthiouracil
Propylthiouracile
Propylthiouracilum
Propythiouracil
Prothiucil
Prothiurone
Prothycil
Prothyran
Protiural
PTU
PTU (thyreostatic)
Thiuragyl
Thyreostat II
Uracil, 6-propyl-2-thio-
ATC H03BA02
CID 657298
CAS 000051525
Drugbank ID DB00550
TTD Drug ID DNC001153
SMILES CCCC1=CC(=O)NC(=S)N1
Formula C7H10N2OS
Molweight 170.232
Atoms 11
LogP 1.385
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
1A1Inducer 15183118
Phase2 interactions
NameReferences
GST 6464504,
9035610
Transporter
AC-No.NameReferences
Q86UG4SLCO6A1 9035610
Extrarenal fraction 0.9
Elimination half-life 1.5h