Compound - Results

Mercaptopurine

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Information Structure
Name Mercaptopurine
Synonyms
1,7-Dihydro-6H-purine-6-thione
1H-Purine, 6-mercapto-
3H-Purine-6-thiol
6 MP
6-Mercaptopurin
6-Mercaptopurine
6-Merkaptopurin
6-MP
6-Purinethiol
6-Thiohypoxanthine
6-Thiopurine
6-Thioxopurine
6H-Purine-6-thione, 1,7-dihydro-
7-Mercapto-1,3,4,6-tetrazaindene
9H-Purine-6(1H)-thione
CCRIS 2761
EINECS 200-037-4
HSDB 3235
Hypoxanthine, Thio-
Ismipur
Leukerin
Leupurin
Mercaleukin
Mercaptopurin
Mercaptopurina
Mercaptopurine
Mercaptopurine (VAN)
Mercaptopurine Anhydrous
Mercaptopurinum
Mercapurin
Merkaptopuryna
Mern
NCI-C04886
NSC 755
NSC-755
Puri-Nethol
Purine, 6-mercapto-
Purine-6-thione
Purinethiol
U-4748
ATC L01BB02
CID 667490
CAS 000050442
Drugbank ID DB01033
TTD Drug ID DAP000147
SMILES S=C1NC=NC2=C1NC=N2
Formula C5H4N4S
Molweight 152.177
Atoms 10
LogP 1.0155
Rotatable Bonds 0
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
1A1Substrate 17691917
Phase2 interactions
NameReferences
MET 10875470,
9450506,
9565678,
16431300,
15354273,
20130603,
8453958
UGT 17691917,
16878443
Transporter
AC-No.NameReferences
O15439MRP/cMOAT-related ABC transporter18300232
Q14542Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter 17088032
Q8TCC7Solute carrier family 22 member 815287899
Q9HAS3Solute carrier family 28 member 316530731
Extrarenal fraction 0.8
Elimination half-life 1.5h