Compound - Results

Estradiol

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Information Structure
Name Estradiol
Synonyms
1,3,5-Estratriene-3,17-beta-diol
17-beta-Estra-1,3,5(10)-triene-3,17-diol
17-beta-Oestra-1,3,5(10)-triene-3,17-diol
17-beta-OH-estradiol
17-beta-OH-oestradiol
17beta-Oestra-1,3,5(10)-triene-3,17-diol
3,17-beta-Dihydroxy-1,3,5(10)-oestratriene
3,17-beta-Dihydroxyestra-1,3,5(10)-triene
3,17-beta-Dihydroxyoestra-1,3,5-triene
3,17-beta-Estradiol
3,17-beta-Oestradiol
3,17-Epidihydroxyestratriene
3,17-Epidihydroxyoestratriene
3,17beta-Dihydroxyestra-1,3,5-triene
3,17beta-Dihydroxyoestra-1,3,5-triene
Aerodiol
Alora
alpha-Estradiol
Altrad
Aquadiol
Bardiol
Beta-estradiol
CCRIS 280
Climaderm
Climara
Climara Forte
Compudose
Compudose 200
Compudose 365
Corpagen
D-3,17-beta-Estradiol
D-3,17-beta-Oestradiol
D-3,17beta-Estradiol
D-3,17beta-Oestradiol
D-Estradiol
D-Oestradiol
Dermestril
Dihydrofollicular Hormone
Dihydrofolliculin
Dihydromenformon
Dihydrotheelin
Dihydroxyestrin
Dihydroxyoestrin
Dimenformon
Diogyn
Diogynets
Divigel
E(sub 2)
EINECS 200-023-8
Encore
Estra-1,3,5(10)-triene-3,17-beta-diol
Estra-1,3,5(10)-triene-3,17-diol, (17beta)-
Estra-1,3,5(10)-triene-3,17beta-diol
Estrace
Estracomb TTS
Estraderm
Estraderm MX
Estraderm TTS
Estraderm TTS 50
Estradiol
Estradiol-17-beta
Estradiol-3,17beta
Estradiolo
Estradiolum
Estraldine
Estrapak 50
Estrasorb
Estreva
Estrifam
Estring
Estroclim 50
Estrodiolum
Estrofem 2
Estrofem Forte
Estrogel
Estrogens, Esterified
Estrovite
Evorel
Extrasorb
Femestral
Femogen
Fempatch
Femtran
Follicyclin
Ginedisc
Ginosedol
Gynergon
Gynestrel
Gynoestryl
GynPolar
HSDB 3589
Lamdiol
Macrodiol
Macrol
Menest
Menorest
Microdiol
Nordicol
NSC-9895
Oesclim
Oestergon
Oestra-1,3,5(10)-triene-3,17-beta-diol
Oestra-1,3,5(10)-triene-3,17beta-diol
Oestradiol
Oestradiol Berco
Oestradiol R
Oestradiol-17-beta
Oestradiol-17beta
Oestradiolum
Oestroglandol
Oestrogynal
Ovahormon
Ovasterol
Ovastevol
Ovociclina
Ovocyclin
Ovocycline
Perlatanol
Primofol
Profoliol
Progynon
Progynon DH
Progynon-DH
Sandrena Gel
Sisare Gel
SK-Estrogens
Syndiol
Systen
Theelin, Dihydro-
Tradelia
Trial SAT
Trocosone
Vagifem
Vivelle
Zerella
Zumenon
ATC G03CA03
CID 450
CAS 000050282
Drugbank ID DB00783
Herbal origin Degelatined Deer-horn
SMILES C[C@@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@H]2O
Formula C18H24O2
Molweight 272.382
Atoms 20
LogP 3.6092
Rotatable Bonds 0
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
1A1Substrate 17570247
15507517
12624000
16207128
11996015
1A2Substrate 16790556
1B1Substrate 17570247
15507517
12624000
11264459
10862525
16207128
2C8Substrate 11741520
2C9Substrate 9625734
9089421
9047321
8204106
11741520
2C19Substrate 11741520
11067738
3A4Substrate 8751044
16790556
3A5Substrate medicine.iupui.edu/flockhart
3A7Substrate medicine.iupui.edu/flockhart
Phase2 interactions
NameReferences
GST 20193744
MET 8055052,
20075204,
8723741,
15377160
SUL 15860265,
1580921,
10076195,
8943792,
16517757,
17954528,
16221673,
19250196,
9010353,
21669803,
9699877,
19356094,
17447568,
19130396,
16601080,
6952616,
14623518,
12227886,
3457954,
16806523,
17433394,
15618673,
16011896,
19299018,
17308787,
19429440,
19219749,
14979917,
6948578,
15809343,
15483196
UGT 14709626,
18719240,
18719240,
2501912,
14871858,
15117964,
16504606,
869904,
8645343,
15593333,
15845768,
12386134
Transporter
AC-No.NameReferences
A2RUN4Dopamine transporter 19115413
O15245Solute carrier family 22 member 112110607
O15431High affinity copper uptake protein 119685012
O15438Canalicular multispecific organic anion transporter 211581266
O95342Bile salt export pump12106615
P33527Multidrug resistance-associated protein 118079363
P46721Organic anion-transporting polypeptide 18779894
P55011Solute carrier family 12 member 215677881
P78381UDP-galactose transporter 17763456
Q4KMT7Uncoupling protein 1 (Mitochondrial, proton carrier) 9716701
Q86UG4SLCO6A1 16407263
Q92887Canalicular multispecific organic anion transporter 118457386
Q9NPD5Solute carrier organic anion transporter family member 1B321278283
Q9NYB5OATPRP519819953
Q9UNQ0Breast cancer resistance protein17823853
Q9Y694Novel liver transporter11879818
Q9Y6L6Sodium-independent organic anion-transporting polypeptide 219427586