Compound - Results

Naphazoline

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Information Structure
Name Naphazoline
Synonyms
1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-
2-(1-Naphthylmethyl)-2-imidazoline
2-(alpha-Naphthylmethyl)-imidazoline
2-(Naphthyl-(1)-methyl)imidazolin
4,5-Dihydro-2-(1-naphthylmethyl)imidazole
5-23-08-00293 (Beilstein Handbook Reference)
alpha-Naphthylmethyl Imidazoline
Antan
BRN 0151864
Ciba 2020/R
Clearine
EINECS 212-641-5
Nafazolina
Nafazoline
Naphazoline
Naphazolinum
Naphthizine
ATC R01AA08
R01AB02
S01GA01
CID 4436
CAS 000835314
Drugbank ID DB06711
TTD Drug ID DAP001408
SMILES C1CN=C(CC2=C3C=CC=CC3=CC=C2)N1
Formula C14H14N2
Molweight 210.274
Atoms 16
LogP 2.1484
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 2
Tetryzoline

Java required.


Information Structure
Name Tetryzoline
Synonyms
1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-
5-23-07-00394 (Beilstein Handbook Reference)
BRN 0011442
EINECS 201-522-3
Tetrahydrozoline
Tetrahydrozolinum
Tetrizolina
Tetryzolin
Tetryzoline
Tetryzolinum
Tyzanol
ATC R01AA06
R01AB03
S01GA02
CID 5419
CAS 000084220
SMILES C1C[C@H](C2=NCCN2)C3=C(C1)C=CC=C3
Formula C13H16N2
Molweight 200.28
Atoms 15
LogP 1.8726
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 2
Xylometazoline

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Information Structure
Name Xylometazoline
Synonyms
5-23-07-00109 (Beilstein Handbook Reference)
Ba-11391
BRN 0180524
EINECS 208-390-6
Otriven
Otrivin
Otrivine
Otrix
Xilometazolina
Xylometazoline
Xylometazolinum
Xylomethazoline
ATC R01AA07
R01AB06
S01GA03
CID 5709
CAS 000526363
Drugbank ID DB06694
SMILES CC1=CC(=CC(C)=C1CC2=NCCN2)C(C)(C)C
Formula C16H24N2
Molweight 244.375
Atoms 18
LogP 2.9095
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 2
Oxymetazoline

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Information Structure
Name Oxymetazoline
Synonyms
2-(4-tert-Butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
5-23-11-00424 (Beilstein Handbook Reference)
6-t-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
BRN 0886303
EINECS 216-079-1
H 990
Hazol
HSDB 3143
Iliadin
Nafrine
Navisin
Nezeril
Oximetazolina
Oximetazolinum
Oxylazine
Oxymetazoline
Oxymetazolinum
Oxymethazoline
Phenol, 3-((4,5-dihydro-1H-imidazol-2-yl)methyl)-6-(1,1-dimethylethyl)-2,4-dimethyl-
Phenol, 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-
Rhinofrenol
Sinerol
ATC R01AA05
R01AB07
S01GA04
CID 4636
CAS 001491594
Drugbank ID DB00935
TTD Drug ID DAP000235
SMILES CC1=CC(=C(O)C(C)=C1CC2=NCCN2)C(C)(C)C
Formula C16H24N2O
Molweight 260.375
Atoms 19
LogP 2.6151
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 3
Phenylephrine

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Information Structure
Name Phenylephrine
Synonyms
(-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl Alcohol
AI3-02402
Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, (R)-
Benzyl Alcohol, M-hydroxy-alpha-((methylamino)methyl)-, (-)-
EINECS 200-424-8
Fenilefrina
HSDB 3383
Isophrin
l-(3-Hydroxyphenyl)-N-methylethanolamine
l-1-(m-Hydroxyphenyl)-2-methylaminoethanol
l-alpha-Hydroxy-beta-methylamino-3-hydroxy-L-ethylbenzene
l-m-Hydroxy-alpha-((methylamino)methyl)benzyl Alcohol
m-Methylaminoethanolphenol
m-Oxedrine
m-Sympathol
m-Sympatol
m-Synephrine
Mesaton
Mesatone
Mesatonum
Metaoxedrin
Metaoxedrine
Metaoxedrinum
Metasympatol
Metasynephrine
Mezaton
Neosynephrine
Phenylephrine
Phenylephrine, L-
Phenylephrinum
R(-)-Phenylephrine
Visadron
ATC C01CA06
R01AA04
R01AB01
R01BA03
S01FB01
S01GA05
CID 6041
CAS 000059427
Drugbank ID DB00388
TTD Drug ID DAP000224
SMILES CNC[C@H](O)C1=CC(O)=CC=C1
Formula C9H13NO2
Molweight 167.205
Atoms 13
LogP 1.0359
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
1A2Inducer 16510159
19AInducer 8863518
Transporter
AC-No.NameReferences
A2RUN4Dopamine transporter 14499136
P11166GLUT-18928747
P55011Basolateral Na-K-Cl symporter10362601
Extrarenal fraction 0.85
Elimination half-life 2.5h
Oxedrine

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Information Structure
Name Oxedrine
Synonyms
1-(4-Hydroxyphenyl)-2-methylaminoethanol
1-(4-Hydroxyphenyl)-N-methylethanolamine
4-Hydroxy-alpha-((methylamino)methyl)benzenemethanol
alpha-(4-Oxyphenyl)alpha-oxy-beta-methylaminoaethan
Analeptin
beta-Methylamino-alpha-(4-hydroxyphenyl)ethyl Alcohol
EINECS 202-300-9
Ethaphene
Methylaminomethyl(4-hydroxyphenyl)carbinol
NSC 166285
Oxedrine
p-Hydroxy-alpha-((methylamino)methyl)benzyl Alcohol
p-Hydroxyphenylmethylaminoethanol
p-Methylaminoethanolphenol
p-Oxedrine
p-Synephrine
Parakorper
Parasympatol
Pentedrin
S 38537-9
Simpalon
Simpatol
Sympaethamine
Sympathol
Sympatol
Synefrin
Synephrin
Synephrine
Synthenate
ATC C01CA08
S01GA06
CID 7172
CAS 000094075
Herbal origin fruit of Seville orange
immature fruit of Seville orange
SMILES CNC[C@@H](O)C1=CC=C(O)C=C1
Formula C9H13NO2
Molweight 167.205
Atoms 12
LogP 1.0359
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 3
Phase2 interactions
NameReferences
NAT 2105376
Transporter
AC-No.NameReferences
A2RUN4Dopamine transporter 14499136
P11166GLUT-18928747
P55011Basolateral Na-K-Cl symporter10362601
Tramazoline

Java required.


Information Structure
Name Tramazoline
Synonyms
EINECS 214-105-6
Tramazolin
Tramazolina
Tramazoline
Tramazolinum
ATC R01AA09
S01GA10
CID 5524
CAS 001082571
SMILES C1CCC2=C(C1)C=CC=C2NC3=NCCN3
Formula C13H17N3
Molweight 215.294
Atoms 16
LogP 1.7739
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 3
Transporter
AC-No.NameReferences
A2RUN4Dopamine transporter 14499136
P11166GLUT-18928747
P55011Basolateral Na-K-Cl symporter10362601