Compound - Results

Acetazolamide

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Information Structure
Name Acetazolamide
Synonyms
1,3,4-Thiadiazole-2-sulfonamide, 5-acetamido-
2-Acetamido-5-sulfonamido-1,3,4-thiadiazole
2-Acetylamino-1,3,4-thiadiazole-5-sulfonamide
5-Acetamide-1,3,4-thiadiazole-2-sulfonamide
6063
Acetamidothiadiazolesulfonamide
Acetamox
Acetazolamid
Acetazolamida
Acetazolamide
Acetazolamidum
AI3-52458
Carbonic Anhydrase Inhibitor No. 6063
CCRIS 5811
Cidamex
Defiltran
Dehydratin
Diacarb
Diakarb
Diamox
Didoc
Diluran
Diuramid
Diureticum-holzinger
Diuriwas
Diutazol
Donmox
Duiramid
Edemox
EINECS 200-440-5
Eumicton
Fonurit
Glaupax
Glupax
HSDB 3002
N-(5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl)acetamide
N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
Natrionex
Nephramid
Nephramide
NSC 145177
Phonurit
SK-acetazolamide
Vetamox
ATC S01EC01
CID 1986
CAS 000059665
Drugbank ID DB00819
TTD Drug ID DAP000600
SMILES CC(=O)NC1=NN=C(S1)S(N)(=O)=O
Formula C4H6N4O3S2
Molweight 222.245
Atoms 13
LogP 0.998
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 7
CYP interactions
NameRelationsReferences
3A4Inhibitor 8877250
Transporter
AC-No.NameReferences
C9JQG1SLC26A4 22116370
Extrarenal fraction 0.02
Elimination half-life 6h
Diclofenamide

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Information Structure
Name Diclofenamide
Synonyms
1,3-Benzenedisulfonamide, 4,5-dichloro-
1,3-Disulfamoyl-4,5-dichlorobenzene
1,3-Disulfamyl-4,5-dichlorobenzene
3,4-Dichloro-5-sulfamylbenzenesulfonamide
4,5-Dichloro-1,3-disulfamoylbenzene
4,5-Dichloro-m-benzenedisulfonamide
4-11-00-00555 (Beilstein Handbook Reference)
Antidrasi
BRN 2703329
CB 8000
Daranide
Dichlofenamide
Dichlorophenamide
Dichlorphenamid
Dichlorphenamide
Diclofenamida
Diclofenamide
Diclofenamidum
EINECS 204-440-6
Glaucol
HSDB 3267
m-Benzenedisulfonamide, 4,5-dichloro-
Oratrol
ATC S01EC02
CID 3038
CAS 000120978
Drugbank ID DB01144
TTD Drug ID DAP000601
SMILES NS(=O)(=O)C1=CC(Cl)=C(Cl)C(=C1)S(N)(=O)=O
Formula C6H6Cl2N2O4S2
Molweight 305.159
Atoms 16
LogP 3.8504
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
2C9Inducer 14557374
Transporter
AC-No.NameReferences
C9JQG1SLC26A4 22116370
Dorzolamide

Java required.


Information Structure
Name Dorzolamide
Synonyms
4S,6S-Dorzolamide
Dorzolamide
ATC S01EC03
CID 3154
CAS 120279961
TTD Drug ID DAP000775
SMILES CCN[C@@H]1C[C@@H](C)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
Formula C10H16N2O4S3
Molweight 324.44
Atoms 19
LogP 3.8648
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
2C8Substrate umm
2C9Substrate umm
11996015
2E1Substrate 7895610
3A4Substrate 11996015
umm
Transporter
AC-No.NameReferences
C9JQG1SLC26A4 22116370
Brinzolamide

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Information Structure
Name Brinzolamide
Synonyms
(R)-4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno(3,2-e)-1,2-thiazine-6-sulfonamide
AL 4862
Azopt
Brinzolamide
ATC S01EC04
CID 68844
CAS 138890627
Drugbank ID DB01194
TTD Drug ID DAP000602
SMILES CCN[C@H]1CN(CCCOC)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
Formula C12H21N3O5S3
Molweight 383.507
Atoms 23
LogP 3.2776
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 8
CYP interactions
NameRelationsReferences
3A4Substrate umm
11996015
Transporter
AC-No.NameReferences
C9JQG1SLC26A4 22116370
Methazolamide

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Information Structure
Name Methazolamide
Synonyms
Methazolamide
2(3H)-ylidene)-
2-Acetylimino-3-methyl-delta(sup 4)-1,3,4-thiadiazoline-5-
4-27-00-08221 (Beilstein Handbook Reference)
5-Acetylimino-4-methyl-delta(sup 2)-1,3,4-thiadiazoline-2-
Acetamide, N-(4-methyl-2-sulfamoyl-delta(2)-1,3,4-
Acetamide, N-(5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-
BRN 0232387
EINECS 209-066-7
HSDB 3269
Metazolamida
Metazolamide
Methazolamide
Methazolamidum
Methenamide
N-(4-Methyl-2-sulfamoyl-delta(sup 2)-1,3,4-thiadiazolin-5-
Neptazane
sulfonamide
thiadiazolin-5-ylidene)-
ylidene)acetamide
ATC S01EC05
CID 4100
CAS 000554574
Drugbank ID DB00703
TTD Drug ID DAP000599
SMILES CN1N=C(SC1=NC(C)=O)S(N)(=O)=O
Formula C5H8N4O3S2
Molweight 236.272
Atoms 14
LogP 0.3573
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
2C9Inhibitor 14739663
2C19Inhibitor 14739663
2D6Inhibitor 14739663
2E1Inhibitor 14739663
3A4Inhibitor 14739663
Transporter
AC-No.NameReferences
C9JQG1SLC26A4 22116370