Compound - Results

Neostigmine

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Information Structure
Name Neostigmine
Synonyms
(m-Hydroxyphenyl)trimethylammonium Dimethylcarbamate (ester)
3-Trimethylammoniumphenyl N,N-dimethylcarbamate
Ammonium, (m-hydroxyphenyl)trimethyl-, Dimethylcarbamate (ester)
Benzenaminium, 3-(((dimethylamino)carbonyl)oxy)-N,N,N-trimethyl-
BRN 3615946
CCRIS 3079
Eustigmin
Eustigmine
HSDB 3921
Intrastigmina
Juvastigmin
m-Trimethylammoniumphenyldimethylcarbamate
Neostigmin
Neostigmine
Neostigminum
Prostigmin
Prostigmine
Vagostigmine
ATC N07AA01
S01EB06
CID 4456
CAS 000059994
Drugbank ID DB01400
TTD Drug ID DAP000563
SMILES CN(C)C(=O)OC1=CC(=CC=C1)[N+](C)(C)C
Formula C12H19N2O2
Molweight 223.291
Atoms 16
LogP 1.9437
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
3A4Inhibitor 11913717
3A5Inhibitor 11913717
3A7Inhibitor 11913717
Extrarenal fraction 0.45
Elimination half-life 1.3h
Pyridostigmine

Java required.


Information Structure
Name Pyridostigmine
Synonyms
3-(((Dimethylamino)carbonyl)oxy)-1-methylpyridinium
5-21-02-00078 (Beilstein Handbook Reference)
BRN 1428269
Pyridostigmine
Pyridostigminum
ATC N07AA02
CID 4991
CAS 000155975
Drugbank ID DB00545
TTD Drug ID DNC001171
SMILES CN(C)C(=O)OC1=C[N+](C)=CC=C1
Formula C9H13N2O2
Molweight 181.212
Atoms 13
LogP 0.5715
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
3A4Inducer 12642463
Extrarenal fraction 0.2
Elimination half-life 1.7h
Distigmine

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Information Structure
Name Distigmine
Synonyms
3,3-(1,6-Hexanediylbis((methylimino)carbonyl)oxy)bis(1-methylpyridinium) Dibromide
3-Hydroxy-1-methylpyridinium Bromide Hexamethylenebis(methylcarbamate)
BC 51
Bromure De Distigmine
Bromuro De Distigmina
Distigmine
Distigmine Bromide
Distigmini Bromidum
EINECS 240-013-0
Hexamarium
Ubretid
Ubritil
ATC N07AA03
CID 27522
CAS 015876672
SMILES CN(CCCCCCN(C)C(=O)OC1=C[N+](C)=CC=C1)C(=O)OC2=C[N+](C)=CC=C2
Formula C22H32Br2N4O4
Molweight 576.322
Atoms 32
LogP -3.5346
Rotatable Bonds 13
H-Bond Donors 0
H-Bond Acceptors 4
Extrarenal fraction 0.15
Elimination half-life 65h
Ambenonium

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Information Structure
Name Ambenonium
Synonyms
Ambenonium
Ambenonium Base
Ambenonium Kation
Ambenonum
ATC N07AA30
CID 2131
CAS 007648988
Drugbank ID DB01122
TTD Drug ID DAP000893
SMILES CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)CC1=C(Cl)C=CC=C1)CC2=C(Cl)C=CC=C2
Formula C28H42Cl2N4O2
Molweight 537.565
Atoms 36
LogP 5.421
Rotatable Bonds 17
H-Bond Donors 0
H-Bond Acceptors 4