Compound - Results

Desipramine

Java required.


Information Structure
Name Desipramine
Synonyms
10,11-Dihydro-5-(3-methylaminopropyl)-5H-dibenz(b,f)azepine
5-(gamma-Methylaminopropyl)iminodibenzyl
5-20-08-00096 (Beilstein Handbook Reference)
5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-
5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-
BRN 1432747
CCRIS 7091
Demethylimipramine
Desimipramine
Desipramin
Desipramina
Desipramine
Desipramine (D4)
Desipraminum
Desmethylimipramine
Dezipramine
Dimethylimipramine
DMI
DMI (pharmaceutical)
DMI 50475
EINECS 200-040-0
HSDB 3052
Imipramine, Demethyl-
Methylaminopropyliminodibenzyl
Monodemethylimipramine
N-(3-Methylaminopropyl)iminobibenzyl
Norimipramine
ATC N06AA01
CID 2995
CAS 000050475
Drugbank ID DB01151
TTD Drug ID DAP001151
SMILES CNCCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2
Formula C18H22N2
Molweight 266.381
Atoms 20
LogP 3.9887
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Substrate 9884317
11996015
umm
2A6Inhibitor umm
2B6Inhibitor umm
2C19Substrate Inhibitor 9884317
15135088
2D6Substrate Inhibitor 9884317
9758674
9205822
10709776
15802801
10895986
14730412
1389951
8880055
15802801
medicine.iupui.edu/flockhart
umm
2E1Inhibitor umm
15135088
9574817
3A4Inhibitor umm
Phase2 interactions
NameReferences
NAT 9774220,
12012027,
7320735,
2105376
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 39495547
O75751Extraneuronal monoamine transporter17727882
P23975Norepinephrine transporter11181015
Q9P2U7Vesicular glutamate transporter 1 15992385
Imipramine

Java required.


Information Structure
Name Imipramine
Synonyms
1-(3-Dimethylaminopropyl)-4,5-dihydro-2,3,6,7-dibenzazepine
2,2-(3-Dimethylaminopropylimino)bibenzyl
2,2-(3-Dimethylaminopropylimino)dibenzyl
5,6-Dihydro-N-(3-(dimethylamino)propyl)-11H-dibenz(b,e)azepine
5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine
5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenzo(b,f)azepine
5-20-08-00096 (Beilstein Handbook Reference)
5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)propyl)-
5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro-
5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-
Antideprin
Berkomine
BRN 0256892
Censtim
Censtin
Dimipressin
Dpid
Dyna-zina
Dynaprin
EINECS 200-042-1
Eupramin
G-22355
HSDB 3100
Imavate
Imidobenzyle
Imipramina
Imipramine
Imipraminum
Imiprin
Imizin
Imizine
Imizinum
Impramine
Intalpram
Iramil
Irmin
Melipramin
Melipramine
N-(3-Dimethylaminopropyl)-o-iminodibenzyl
N-(gamma-Dimethylaminopropyl)iminodibenzyl
Nelipramin
NSC 169866
Prazepine
Promiben
Psychoforin
Surplix
Timolet
Tofranil
ATC N06AA02
CID 3696
CAS 000050497
Drugbank ID DB01151
TTD Drug ID DAP001154
SMILES CN(C)CCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2
Formula C19H24N2
Molweight 280.407
Atoms 21
LogP 3.94
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Substrate Inhibitor 9351907
11990081
2B6Substrate 9190854
2C18Substrate 9190854
2C19Substrate Inhibitor 12065442
11532381
8835703
8521680
1464
12065442
9190854
9884317
11996015
2D6Substrate Inhibitor 8565792
8866826
9884317
9205822
2060250
16141545
9205822
11532381
15687478
2E1Inhibitor 9574817
11996015
3A4Substrate 9278210
9190854
3A7Substrate 10534316
Phase2 interactions
NameReferences
GST 15094841
MET 6686446,
6686446
NAT 19023179,
133361
UGT 21497036,
17495417,
20133892,
8820428,
15470160,
12019188
Transporter
AC-No.NameReferences
P78381UDP-galactose transporter 15470160
Q05940Synaptic vesicular amine transporter 8373164
Extrarenal fraction 1
Elimination half-life 12h
Imipramine Oxide

Java required.


Information Structure
Name Imipramine oxide
Synonyms
EINECS 229-907-1
Imipramine N-oxide
Imipramine Oxide
Imipraminoxide
Imipraminoxido
Imipraminoxidum
ATC N06AA03
CID 65589
CAS 006829987
SMILES C[N+](C)([O-])CCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2
Formula C19H24N2O
Molweight 296.407
Atoms 22
LogP 3.9735
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Substrate 8502233
3A4Substrate 8502233
Transporter
AC-No.NameReferences
P78381UDP-galactose transporter 15470160
Q05940Synaptic vesicular amine transporter 8373164
Clomipramine

Java required.


Information Structure
Name Clomipramine
Synonyms
3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine
3-Chloroimipramine
5-20-08-00103 (Beilstein Handbook Reference)
5H-Dibenz(b,f)azepine, 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-
Anafranil (free Base)
Anafranil Base
BRN 1323477
Chlorimipramine
Clomipramina
Clomipramine
Clomipraminum
EINECS 206-144-2
Hydiphen
Monochlorimipramine
NSC 169865
ATC N06AA04
CID 2801
CAS 000303491
Drugbank ID DB01242
TTD Drug ID DAP000742
SMILES CN(C)CCCN1C2=CC=CC=C2CCC3=CC=C(Cl)C=C13
Formula C19H23ClN2
Molweight 314.852
Atoms 22
LogP 4.5934
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Substrate 9231305
15199661
2C19Substrate 15199661
11763000
8667235
15199661
2D6Substrate Inhibitor 15199661
7741408
15199661
11763000
8667235
15252821
7741408
3A4Substrate 8667235
15199661
Phase2 interactions
NameReferences
GST 15094841
UGT 20133892
Transporter
AC-No.NameReferences
Q86UG4Solute carrier family 21 member 1915094841
Extrarenal fraction 1
Elimination half-life 24h
Opipramol

Java required.


Information Structure
Name Opipramol
Synonyms
4-(3-(5H-Dibenz(b,f)azepin-5-yl)propyl)-1-piperazineethanol
5-23-01-00475 (Beilstein Handbook Reference)
5H-Dibenz(b,f)azepine, 5-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-
BRN 0627076
EINECS 206-254-0
N-(3-(4-(2-Hydroxyethyl)piperazino)propyl)iminostilbene
Nisidana
NSC 169867
Opipramol
Opipramol G
Opipramolum
ATC N06AA05
CID 9417
CAS 000315720
SMILES OCCN1CCN(CCCN2C3=C(C=CC=C3)C=CC4=C2C=CC=C4)CC1
Formula C23H29N3O
Molweight 363.496
Atoms 27
LogP 3.2493
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2D6Substrate 11996015
FachInfo
Transporter
AC-No.NameReferences
Q86UG4Solute carrier family 21 member 1915094841
Trimipramine

Java required.


Information Structure
Name Trimipramine
Synonyms
1-(3-Dimethylamino-2-methylpropyl)-4,5-dihydro-2,3:6,7-dibenzazepine
10,11-Dihydro-5-(3-dimethylamino-2-methylpropyl)-5H-dibenz(b,f)azepine
2-Metil-3-dimetilamino-propil-5-iminodibenzile
5-(3-(Dimethylamino)-2-methylpropyl)-10,11-dihydro-5H-dibenz(b,f)azepine
5-(gamma-Dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo(b,f)azepine
5-20-08-00099 (Beilstein Handbook Reference)
5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)-2-methylpropyl)-
5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-
7162 RP
beta-Methylimipramine
BRN 1321466
EINECS 212-008-3
FI 6120
IL 6001
Sapilent
Surmontil
Trimeprimina
Trimeprimine
Trimipramina
Trimipramine
Trimipraminum
ATC N06AA06
CID 5584
CAS 000739719
Drugbank ID DB00726
TTD Drug ID DAP001153
SMILES C[C@H](CN(C)C)CN1C2=C(CCC3=C1C=CC=C3)C=CC=C2
Formula C20H26N2
Molweight 294.434
Atoms 22
LogP 4.186
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
2C9Substrate 14520122
2C19Substrate 14520122
2D6Substrate umm
14520122
16342006
14646691
3A4Substrate umm
Phase2 interactions
NameReferences
UGT 20133892
Transporter
AC-No.NameReferences
Q86UG4Solute carrier family 21 member 1915094841
Extrarenal fraction 0.9
Elimination half-life 24h
Lofepramine

Java required.


Information Structure
Name Lofepramine
Synonyms
4-Chlor-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)acetophenon
Amplit
DB 2182
EINECS 245-396-8
LEO 640
Lofepramina
Lofepramine
Lofepraminum
Lopramine
ATC N06AA07
CID 3947
CAS 023047258
SMILES CN(CCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2)CC(=O)C4=CC=C(Cl)C=C4
Formula C26H27ClN2O
Molweight 418.958
Atoms 30
LogP 5.8465
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
2D6Substrate
Transporter
AC-No.NameReferences
Q86UG4Solute carrier family 21 member 1915094841
Extrarenal fraction 1
Elimination half-life 2.2h
Dibenzepin

Java required.


Information Structure
Name Dibenzepin
Synonyms
10-(2-(Dimethylamino)ethyl)-5-methyl-5H-dibenzo(b,e)(1,4)diazepin-11(10H)-one
5,10-Dihydro-10-(2-(dimethylamino)ethyl)-5-methyl-11H-dibenzo(b,e)(1,4)diazepin-11-one
5-24-04-00112 (Beilstein Handbook Reference)
5H-Dibenzo(b,e)(1,4)diazepin-11(10H)-one, 10-(2-(dimethylamino)ethyl)-5-methyl-
BRN 0894708
Dibenzepin
Dibenzepina
Dibenzepine
Dibenzepinum
ATC N06AA08
CID 9419
CAS 004498322
SMILES CN(C)CCN1C(=O)C2=CC=CC=C2N(C)C3=C1C=CC=C3
Formula C18H21N3O
Molweight 295.379
Atoms 22
LogP 2.617
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 2
Transporter
AC-No.NameReferences
Q86UG4Solute carrier family 21 member 1915094841
Amitriptyline

Java required.


Information Structure
Name Amitriptyline
Synonyms
10,11-Dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-delta(sup 5),gamma-propylamine
3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)-N,N-dimethylpropylamin
3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(3-Dimethylaminopropylidene)-dibenzo-(a,d)(1,4)-cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(gamma-Dimethylaminopropylidine)-5H-dibenzo(a,d)(1,4)cycloheptadiene
5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-
Adepress
Adepril
Amitriptilina
Amitriptylin
Amitriptyline
Amitriptylinum
Amytriptylin
BRN 2217885
Damilen
Damitriptyline
EINECS 200-041-6
Elavil
Flavyl
HSDB 3007
Lantron
MK 230
N 750
Proheptadiene
Redomex
Ro 4-1575
Seroten
Triptanol
Triptilin
Triptisol
Tryptanol
ATC N06AA09
CID 2160
CAS 000050486
Drugbank ID DB00321
TTD Drug ID DAP000864
SMILES CN(C)CCC=C1/C2=C(CCC3=C1C=CC=C3)C=CC=C2
Formula C20H23N
Molweight 277.403
Atoms 21
LogP 4.1686
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Substrate Inhibitor umm
15199661
9549641
11990081
2B6Substrate 11259560
2C8Substrate Inhibitor umm
11136296
2C9Substrate umm
9131945
2C19Substrate Inhibitor 9867310
9923577
12172336
umm
9549641
9399333
2D6Substrate Inhibitor 12172336
16175144
9143866
medicine.iupui.edu/flockhart
9131945
11259560
11888334
9143866
2E1Substrate Inhibitor 9549641
9574817
11996015
umm
3A4Substrate Inhibitor umm
9131945
9549641
16415122
17598095
3A5Substrate 11136296
14637191
Phase2 interactions
NameReferences
UGT 20133892,
17495417,
21497036
Transporter
AC-No.NameReferences
P23975NET21129446
P78381UDP-Gal-Tr11355849
Extrarenal fraction 0.9
Elimination half-life 15.0h
Nortriptyline

Java required.


Information Structure
Name Nortriptyline
Synonyms
10,11-Dihydro-5-(3-methylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptene
10,11-Dihydro-N-methyl-5H-dibenzo(a,d)cycloheptene-delta(5,gamma)-propylamine
3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methylpropylamine
5-(3-(Methylamino)propylidene)dibenzo(a,e)cyclohepta(1,5)diene
5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(alpha-Methylaminopropylidene)dibenzo(a,d)cyclohepta(1,4)diene
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N-methyl-
Amitryptyline, Demethyl-
Ateben
Avantyl
Aventyl
BRN 2216786
Demethylamitriptyline
Demethylamitryptyline
Desitriptilina
Desmethylamitriptyline
EINECS 200-788-8
HSDB 3371
Lumbeck
N-Methyl-3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)propylamin
Noramitriptyline
Noritren
Nortriptilina
Nortriptyline
Nortriptylinum
Nortryptiline
Nortryptyline
Sensaval
ATC N06AA10
CID 4543
CAS 000072695
Drugbank ID DB00540
TTD Drug ID DAP001152
SMILES CNCCC=C1/C2=C(CCC3=C1C=CC=C3)C=CC=C2
Formula C19H21N
Molweight 263.377
Atoms 20
LogP 4.2173
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Substrate 9193876
2C19Substrate 9867310
9193876
2D6Substrate Inhibitor 9193876
7808430
10709776
10354960
12398564
9342584
2E1Inhibitor 9574817
11996015
3A4Substrate 10677595
10354960
Transporter
AC-No.NameReferences
P23975NET21129446
P78381UDP-Gal-Tr11355849
Extrarenal fraction 1
Elimination half-life 30h
Protriptyline

Java required.


Information Structure
Name Protriptyline
Synonyms
5-(3-Methylaminopropyl)-5H-dibenzo(a,d)cycloheptene
5H-Dibenzo(a,d)cycloheptene-5-propanamine, N-methyl-
5H-Dibenzo(a,d)cycloheptene-5-propylamine, N-methyl-
7-(3-Methylaminopropyl)-1,2:5,6-dibenzocycloheptatriene
Amimetilina
BRN 2217411
EINECS 207-119-9
HSDB 3391
N-3-(5H-Dibenzo(a,d)cyclohepten-5-yl)propyl-N-methylamine
N-Methyl-5H-dibenzo(a,d)cycloheptene-5-propylamine
Protriptilina
Protriptyline
Protriptylinum
Protryptyline
Triptil
ATC N06AA11
CID 4976
CAS 000438608
Drugbank ID DB00344
TTD Drug ID DAP000863
SMILES CNCCC[C@H]1C2=C(C=CC=C2)C=CC3=C1C=CC=C3
Formula C19H21N
Molweight 263.377
Atoms 20
LogP 4.6928
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
2D6Substrate umm
Transporter
AC-No.NameReferences
P23975NET21129446
P78381UDP-Gal-Tr11355849
Doxepin

Java required.


Information Structure
Name Doxepin
Synonyms
1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N,N-dimethyl-
11-(3-(Dimethylamino)propylidene)-6H-dibenz(b,e)oxepine
11-(3-Dimethylamino-propyliden)-6,11-dihydro-dibenz(b,e)oxipin
11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz(b,e)oxipin
Dibenz(b,e)oxepin-delta(11(6H),gamma)-propylamine, N,N-dimethyl-
Doxepin
Doxepina
Doxepine
Doxepinum
HSDB 3069
MF 10
N,N-Dimethyldibenz(b,e)oxepin-delta(11(6H),gamma)-propylamine
ATC N06AA12
CID 3158
CAS 001668195
SMILES CN(C)CCC=C1/C2=C(COC3=C1C=CC=C3)C=CC=C2
Formula C19H21NO
Molweight 279.376
Atoms 21
LogP 3.9624
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
1A2Substrate 12180536
umm
2C9Substrate 12180536
12360109
2C19Substrate 12180536
12180536
12360109
2D6Substrate Inhibitor 15520506
12360109
15520506
umm
11037801
12360109
3A4Substrate umm
Phase2 interactions
NameReferences
GST 15094841
Transporter
AC-No.NameReferences
P23975NET21129446
P78381UDP-Gal-Tr11355849
Extrarenal fraction 1
Elimination half-life 17h
Iprindole

Java required.


Information Structure
Name Iprindole
Synonyms
1-(3-Dimethylaminopropyl)-2,3-hexamethyleneindole
5-(3-(Dimethylamino)propyl)-6,7,8,9,10,11-hexahydro-5H-cyclooct(b)indole
BRN 1386299
EINECS 226-933-5
Galatur
Iprindol
Iprindole
Iprindolum
NSC 169449
Pramindole
Prondol
Tertran
WY-3263
Wy-3263 (VAN)
ATC N06AA13
CID 21722
CAS 005560725
SMILES CN(C)CCCN1C2=C(CCCCCC2)C3=C1C=CC=C3
Formula C19H28N2
Molweight 284.439
Atoms 21
LogP 4.252
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
Transporter
AC-No.NameReferences
P23975NET21129446
P78381UDP-Gal-Tr11355849
Melitracen

Java required.


Information Structure
Name Melitracen
Synonyms
9-(3-Dimetilaminopropyliden)-10,10-dimetil-9,10-diidroanthracene
Adaptol
BRN 1980107
Dixeran
EINECS 225-858-5
Melitracen
Melitracene
Melitraceno
Melitracenum
N 7001
N,N,10,10-Tetramethyl-delta(sup 9(10),gamma)-anthracenepropylamine
Thymeol
Trausabun
U-24973
ATC N06AA14
CID 25382
CAS 005118296
SMILES CN(C)CCC=C1C2=CC=CC=C2C(C)(C)C3=C1C=CC=C3
Formula C21H25N
Molweight 291.43
Atoms 22
LogP 4.7093
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 1
Transporter
AC-No.NameReferences
P23975NET21129446
P78381UDP-Gal-Tr11355849
Butriptyline

Java required.


Information Structure
Name Butriptyline
Synonyms
10,11-Dihydro-beta,N,N-trimethyl-5H-dibenzo(a,d)cycloheptene-5-propylamine
BRN 2814611
Butriptyline
ATC N06AA15
CID 21772
CAS 015686370
SMILES C[C@@H](C[C@@H]1C2=C(CCC3=C1C=CC=C3)C=CC=C2)CN(C)C
Formula C21H27N
Molweight 293.446
Atoms 22
LogP 4.5049
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
Transporter
AC-No.NameReferences
P23975NET21129446
P78381UDP-Gal-Tr11355849
Dosulepin

Java required.


Information Structure
Name Dosulepin
Synonyms
11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepin
3-(6,11-Dihydrodibenzo(b,e)thiepin-11-yliden)-N,N-dimethylpropylamin
3-(6H-Dibenzo(b,e)thiepin-11-yliden)-N,N-dimethylpropylamin
3-Dibenzo(b,e)thiepin-11(6H)-ylidene-N,N-dimethyl-1-propamine
Dosulepin
Dosulepina
Dosulepine
Dosulepinum
Dothiepin
EINECS 204-031-2
IZ 914
N,N-Dimethyldibenzo(b,e)thiepin-delta-sup(11(6H),gamma)propylamine
Prothiaden
Prothiaden Spofa
Prothiadene
ATC N06AA16
CID 5282426
CAS 000113531
SMILES CN(C)CCC=C1C2=C(CSC3=C1C=CC=C3)C=CC=C2
Formula C19H21NS
Molweight 295.442
Atoms 22
LogP 4.6757
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 1
Transporter
AC-No.NameReferences
P23975NET21129446
P78381UDP-Gal-Tr11355849
Amoxapine

Java required.


Information Structure
Name Amoxapine
Synonyms
2-Chlor-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepin
2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine
Amoxan
Amoxapina
Amoxapine
Amoxapinum
Asendin
BRN 0832057
CL 67772
Demolox
Desmethylloxapin
EINECS 237-867-1
Moxadil
ATC N06AA17
CID 2170
CAS 014028445
Drugbank ID DB00543
TTD Drug ID DAP001149
SMILES ClC1=CC2=C(OC3=C(C=CC=C3)N=C2N4CCNCC4)C=C1
Formula C17H16ClN3O
Molweight 313.781
Atoms 22
LogP 3.1315
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 3
Transporter
AC-No.NameReferences
Q9Y345SLC6A517640406
Dimetacrine

Java required.


Information Structure
Name Dimetacrine
Synonyms
10-(3-(Dimethylamino)propyl)-9,9-dimethylacridan
5-20-08-00134 (Beilstein Handbook Reference)
9,9-Dimethyl-10-(3-(dimethylamino)propyl)acridan
BRN 1349663
Dimetacrina
Dimetacrine
Dimetacrino
Dimetacrinum
Dimethacin
Dimethacine
Dimethacrin
Dimethacrine
N,N,9,9-Tetramethyl-10(9H)-acridinepropanamine
NSC 100297
ATC N06AA18
CID 94280
CAS 004757555
SMILES CN(C)CCCN1[C@H]2C=CCC=C2C(C)(C)C3=C1C=CC=C3
Formula C20H26N2
Molweight 294.434
Atoms 22
LogP 4.4807
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
Transporter
AC-No.NameReferences
Q9Y345SLC6A517640406
Amineptine

Java required.


Information Structure
Name Amineptine
Synonyms
7-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)amino)heptanoic Acid
Amineptin
Amineptine
Amineptino
Amineptinum
BRN 2170218
EINECS 260-818-0
EU 1694
S 1694
Survector
ATC N06AA19
CID 34870
CAS 057574091
SMILES OC(=O)CCCCCCN[C@@H]1C2=C(CCC3=C1C=CC=C3)C=CC=C2
Formula C22H27NO2
Molweight 337.455
Atoms 25
LogP 4.8902
Rotatable Bonds 8
H-Bond Donors 0
H-Bond Acceptors 3
Transporter
AC-No.NameReferences
Q9Y345SLC6A517640406
Maprotiline

Java required.


Information Structure
Name Maprotiline
Synonyms
276-Ba
3-(9,10-Dihydro-9,10-ethanoanthracen-9-yl)propylmethylamine
BRN 2385493
EINECS 233-599-4
Maprotilina
Maprotiline
Maprotilinum
Maprotylina
N-Methyl-9,10-ethanoanthracene-9(10H)-propylamine
ATC N06AA21
CID 4011
CAS 010262698
Drugbank ID DB00934
TTD Drug ID DAP001150
SMILES CNCCC[C@@]12CC[C@@H](C3=C1C=CC=C3)C4=C2C=CC=C4
Formula C20H23N
Molweight 277.403
Atoms 21
LogP 4.6023
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Substrate 12071336
2D6Substrate 12071336
12071336
Transporter
AC-No.NameReferences
Q9Y345SLC6A517640406
Extrarenal fraction 1
Elimination half-life 45h
Quinupramine

Java required.


Information Structure
Name Quinupramine
Synonyms
5-(3-Chinuclidinyl)-10,11-dihydro-5H-dibenz(b,f)azepin
EINECS 250-780-3
Quinupramina
Quinupramine
Quinupraminum
ATC N06AA23
CID 93154
CAS 031721172
SMILES C1CN2CC[C@@H]1[C@@H](C2)N3C4=C(CCC5=C3C=CC=C5)C=CC=C4
Formula C21H24N2
Molweight 304.429
Atoms 23
LogP 4.0204
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 1
Transporter
AC-No.NameReferences
Q9Y345SLC6A517640406