Compound - Results

Methaqualone

Java required.


Information Structure
Name Methaqualone
Synonyms
2-Methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
2-Methyl-3-(2-methylphenyl)-4-quinazolinone
2-Methyl-3-(2-tolyl)quinazol-4-one
2-Methyl-3-(o-tolyl)-3,4-dihydro-4-quinazolinone
2-Methyl-3-o-tolyl-4(3H)-chinazolinon
2-Methyl-3-o-tolyl-4(3H)-chinazolone
2-Methyl-3-o-tolyl-4(3H)-quinazolinone
2-Methyl-3-o-tolyl-4-quinazolone
2-Methyl-3-tolyl-4-oxybensdiazine
3,4-Dihydro-2-methyl-4-oxo-3-o-tolylquinazoline
5-24-03-00132 (Beilstein Handbook Reference)
Aqual
BRN 0211874
Cateudyl
CI-705
Citexal
CN 38703
Dormigoa
Dormigoa-Schlafmittel
Dormogen
Dormutil
Dorsedin
EINECS 200-780-4
Fadormir
Holodorm
HSDB 3120
Hyminal
Hypocol
Hyptor
Hyptor Base
Ipnofil
MAOA
Melsed
Melsedin Base
Melsomin
Mequin
Metachalon
Metacualona
Metakvalon
Metaqualon
Metaqualone
Methachalonum
Methaqualon
Methaqualone
Methaqualoneinone
Methaqualonum
Methased
Methyl-o-tolylquinazolone
Metolquizolone
Mollinox
Motolon
Mozambin
MTQ
Nobedorm
Noctilene
Normi-nox
NSC 111388
Omnyl
Optinoxan
Orthonal
Ortonal
Parminal
Pro-Dorm
Quaalude
QZ 2
R-148
Revonal
RIC 272
Rorer 148
Rorer 714
Roulone
Rouqualone
Sindesvel
Somberol
Somnafac
Somnomed
Sonal
Sopor
Soverin
Torinal
TR-495
Tuazole
Tuazolone
ATC N05CM01
CID 6292
CAS 000072446
SMILES CC1=C(C=CC=C1)N2C(C)=NC3=C(C=CC=C3)C2=O
Formula C16H14N2O
Molweight 250.295
Atoms 19
LogP 3.0025
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
3A4Substrate 12900872
Extrarenal fraction 0.9
Elimination half-life 24h
Clomethiazole

Java required.


Information Structure
Name Clomethiazole
Synonyms
4-27-00-00990 (Beilstein Handbook Reference)
4-Methyl-5-(beta-chloroethyl)thiazole
5-(2-Chloroethyl)-4-methylthiazole
BRN 0114244
Chlorethiazol
Chlorethiazole
Chlormethiazol
Chlormethiazole
Chloro-S.C.T.Z.
Clomethiazol
Clomethiazole
Clomethiazolum
Clometiazol
Clometiazole
Clometiazolo
Distraneurin
EINECS 208-565-7
Emineurina
Somnevrin
WY 1485
ATC N05CM02
CID 10783
CAS 000533459
SMILES CC1=C(CCCl)SC=N1
Formula C6H8ClNS
Molweight 161.652
Atoms 9
LogP 2.2328
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
2A6Substrate 11996015
2B6Substrate 11996015
2C19Substrate 11996015
2E1Inhibitor 16799984
9328319
3A4Substrate 11996015
Extrarenal fraction 0.95
Elimination half-life 6h
Bromisoval

Java required.


Information Structure
Name Bromisoval
Synonyms
(alpha-Bromoisovaleryl)urea
2-Bromisovalerylmocovina
2-Bromo-3-methylbutyrylurea
2-Monobromoisovalerylurea
3-03-00-00123 (Beilstein Handbook Reference)
Abroval
Alluval
alpha-Bromo-beta-dimethylpropanoylurea
alpha-Bromoisovaleric Acid Ureide
alpha-Bromoisovaleroylurea
Alural
BRN 1773255
Bromaral
Bromcarbamide
Bromisoval
Bromisovalerylurea
Bromisovalum
Bromizoval
Bromocarbamide
Bromoisovalum
Bromoval
Bromovalerocarbamide
Bromovalerylurea
Bromoxil
Bromural
Bromuvan
Bromvalerocarbamidum
Bromvalerylurea
Bromvaletone
Bromvaletonum
Bromvalurea
Brovalin
Brovalurea
Brovarin
Calmotin
Dagrabromyl
Dibroluur
Dormigene
EINECS 207-825-7
Isobromyl
Monobromoisolvalerylurea
N-(Aminocarbonyl)-2-bromo-3-methylbutanamide
Pivadorm
Pivadorn
Somnurol
Upiol
Uvaleral
ATC N05CM03
CID 2447
CAS 000496673
SMILES CC(C)[C@H](Br)C(=O)NC(N)=O
Formula C6H11BrN2O2
Molweight 223.068
Atoms 11
LogP 1.692
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 4
Carbromal

Java required.


Information Structure
Name Carbromal
Synonyms
(2-Brom-2-ethylbutyryl)harnstoff
(2-Bromo-2-ethylbutyryl)urea
(alpha-Bromo-alpha-ethylbutyryl)carbamide
(alpha-Bromo-alpha-ethylbutyryl)urea
1-Bromo-ethyl-butyryl-urea
2-Brom-2-ethylbutyrylmocovina
4-03-00-00117 (Beilstein Handbook Reference)
Adalin
Addisomnol
AI3-51262
alpha-Ethyl-alpha-bromobutyrylurea
BRN 1775637
Bromacetocarbamide
Bromacetocarbamidum
Bromadal
Bromdiethylacetylurea
Bromodiethylacetylcarbamide
Bromodiethylacetylurea
Butanamide, N-(aminocarbonyl)-2-bromo-2-ethyl-
Carbromal
Carbromalum
CCRIS 124
Diacid
Dormiturin
EINECS 201-046-6
Fydalin
Hoggar
HSDB 4100
Karbromal
Kartryl
Mirfudorm
N-(Aminocarbonyl)-2-bromo-2-ethylbutanamide
NCI-C03805
Nenesin
NSC 49191
Nyctal
Parkosed
Pelidorm
Persomnin
Pianadalin
Planadalin
Servadorm
Somben
Thalambrol
Tildin
Uradal
Urea, (2-bromo-2-ethylbutyryl)-
ATC N05CM04
CID 6488
CAS 000077656
SMILES CCC(Br)(CC)C(=O)NC(N)=O
Formula C7H13BrN2O2
Molweight 237.094
Atoms 12
LogP 2.2262
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 4
Scopolamine

Java required.


Information Structure
Name Scopolamine
Synonyms
(-)-Hyoscine
(-)-Scopolamine
1alphaH,5alphaH-Tropan-3alpha-ol, 6beta,7beta-epoxy-, (-)-tropate (ester)
3-Oxa-9-azatricyclo(3.3.1.0(sup 2,4))nonan-7-ol, 9-methyl-, Tropate (ester)
3-Oxa-9-azatricyclo(3.3.1.O(sup 2,4))nonan-7-ol, 9-methyl-, Tropate (ester)
6,7-Epoxytropine Tropate
6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropate
6beta,7beta-Epoxy-1alpha,5alpha-tropan-3alpha-ol
6beta,7beta-Epoxy-3alpha-tropanyl S-(-)-tropate
alpha-(Hydroxymethyl)benzeneacetic Acid 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(2.4))non-7-yl Ester
Atrochin
Atroquin
EINECS 200-090-3
Epoxytropine Tropate
HSDB 4074
Hyoscine
Hyosol
l-Scopolamine
Oscine
Scopine (-)-tropate
Scopine Tropate
Scopolamine
SEE
Skopolamin
Transderm-Scop
Tropic Acid, 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(sup 2,4))non-7-yl Ester
Tropic Acid, Ester With Scopine
ATC A04AD01
N05CM05
S01FA02
CID 153311
CAS 000051343
Herbal origin Calcined Alum
Datura Flower
root of corydalis
SMILES CN1C2CC(CC1C3OC23)OC(=O)C(CO)C4=CC=CC=C4
Formula C17H21NO4
Molweight 303.353
Atoms 28
LogP 0.856
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 5
Extrarenal fraction 0.9
Elimination half-life 1.5h
Propiomazine

Java required.


Information Structure
Name Propiomazine
Synonyms
1-(10-(2-(Dimethylamino)propyl)phenothiazin-2-yl)-1-propanone
1-Propanone, 1-(10-(2-(dimethylamino)propyl)-10H-phenothiazin-2-yl)-
1-Propanone, 1-(10-(2-(dimethylamino)propyl)phenothiazin-2-yl)-
10-(2-Dimethylaminopropyl)-2-propionylphenothiazine
10-Dimethylaminoisopropyl-2-propionylphenothiazine
2-Propionyl-10-(2-(dimethylamino)propyl)phenothiazine
3-Propionyl-10-dimethylaminoisopropylphenothiazine
CB 1678
EINECS 206-646-1
HSDB 3275
Phenoctyl
Propiomazina
Propiomazine
Propiomazinum
Propionylpromethazine
Wy-1359
ATC N05CM06
CID 4940
CAS 000362298
Drugbank ID DB00777
TTD Drug ID DAP000327
SMILES CCC(=O)C1=CC2=C(SC3=C(C=CC=C3)N2C[C@H](C)N(C)C)C=C1
Formula C20H24N2OS
Molweight 340.482
Atoms 24
LogP 4.8971
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 2
Triclofos

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Information Structure
Name Triclofos
Synonyms
2,2,2-Trichloroethanol Dihydrogen Phosphate
2,2,2-Trichloroethyl Dihydrogen Phosphate
2,2,2-Trichloroethyl Phosphate
BRN 1841552
EINECS 206-185-6
Ethanol, 2,2,2-trichloro-, Dihydrogen Phosphate
HSDB 3276
Phosphoric Acid, 2,2,2-trichloroethyl Ester
Sch 10159
Trichlophos
Trichlorethyl Phosphate
Trichloroethanol 1-phosphate
Trichloroethanol-1-phosphate
Trichloroethyl Dihydrogen Phosphate
Trichloroethyl Phosphate
Trichloryl
Triclofos
Triclofosa
Triclofoso
Triclofosum
Tricloryl
Triclos
ATC N05CM07
CID 5563
CAS 000306525
SMILES OP(O)(=O)OCC(Cl)(Cl)Cl
Formula C2H4Cl3O4P
Molweight 229.384
Atoms 10
LogP 1.4659
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 4
Ethchlorvynol

Java required.


Information Structure
Name Ethchlorvynol
Synonyms
1-Chloro-3-ethyl-1-penten-4-yn-3-ol
1-Chloro-3-ethylpent-1-4-yn-3-ol
1-Penten-4-yn-3-ol, 1-chloro-3-ethyl-
3-(beta-Chlorovinyl)-1-pentyn-3-ol
4-01-00-02315 (Beilstein Handbook Reference)
5-Chloro-3-ethylpent-1-yn-4-en-3-ol
A 71
Aethyl-chlorvynol
AI3-23721
Alvinol
Arvynol
beta-Chlorovinyl Ethyl Ethynyl Carbinol
beta-Chlorvinyl Ethyl Ethynyl Carbinol
BRN 1702245
Etchlorvinolo
Etclorvinol
Ethchlorovynol
Ethchlorvinol
Ethchlorvinyl
Ethchlorvynol
Ethchlorvynolum
Ethclorvynol
Ethochlorvynol
Ethychlorvynol
Ethyl Beta-chlorovinyl Ethynyl Carbinol
HSDB 3079
Normonson
Normosan
Normoson
Nostel
NSC 30372
Placidil
Placidyl
Roeridorm
Serenil
Serensil
ATC N05CM08
CID 3281
CAS 000113188
TTD Drug ID DAP000163
SMILES CC[C@](O)(C=CCl)C#C
Formula C7H9ClO
Molweight 144.599
Atoms 11
LogP 1.5132
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 1
Hexapropymate

Java required.


Information Structure
Name Hexapropymate
Synonyms
1-(2-Propynyl)-1-cyclohexanol Carbamate
1-(2-Propynyl)cyclohexanol Carbamate
1-(2-Propynyl)cyclohexyl Carbamate
1-Carbamoyloxy-1-(2-propynyl)cyclohexane
4-06-00-00362 (Beilstein Handbook Reference)
BRN 3253991
Carbamate Du Propinylcyclohexanol
Carbamic Acid, 1-(2-propynyl)cyclohexyl Ester
Cyclohexanol, 1-(2-propynyl)-, Carbamate
EINECS 206-618-9
Esapropimato
Hexapropimato
Hexapropymate
Hexapropymatum
Hexopropynate
L 2103
L-2103
LF 62
Lunamin
Merinax
Modirax
NSC 169094
Propynylcyclohexanol Carbamate
ATC N05CM10
CID 9661
CAS 000358521
SMILES NC(=O)O[C@]1(CCCCC1)CC#C
Formula C10H15NO2
Molweight 181.232
Atoms 13
LogP 2.5082
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 3
Bromides

Java required.


Information Structure
Name Bromides
Synonyms
Bromide
Bromide Ions
Bromides
Caswell No. 499D
EPA Pesticide Chemical Code 053200
Inorganic Bromides
ATC N05CM11
CID 259
CAS 024959679
SMILES [Br-]
Formula Br
Molweight 79.904
Atoms 1
LogP -2.996
Rotatable Bonds 0
H-Bond Donors 0
H-Bond Acceptors 0
Transporter
AC-No.NameReferences
O15244hOCT219833842
Apronal

Java required.


Information Structure
Name Apronal
Synonyms
(2-Isopropyl-4-pentenoyl)urea
4-03-00-00120 (Beilstein Handbook Reference)
Allylisopropylacetylcarbamide
Allylisopropylacetylurea
Apronal
Apronalide
BRN 1775529
EINECS 208-443-3
Isodormid
Isopropylallylazetylkarbamid
N-(Aminocarbonyl)-2-(1-methylethyl)-4-pentenamide
Sedormid
ATC N05CM12
CID 10715
CAS 000528927
SMILES CC(C)[C@@H](CC=C)C(=O)NC(N)=O
Transporter
AC-No.NameReferences
O15244hOCT219833842
Valnoctamide

Java required.


Information Structure
Name Valnoctamide
Synonyms
2-Ethyl-3-methylvaleramide
3-02-00-00812 (Beilstein Handbook Reference)
alpha-Ethyl-beta-methyl-valeramide
Amid Kyseliny 2-ethyl-3-methylvalerove
Axiquel
BRN 1749434
EINECS 224-033-7
Ethylmethyl Valeramide
McN-X-181
MI 181
Nirvanil
NSC 34092
NSC-32363
Pentanamide, 2-ethyl-3-methyl-
Valmetamide
Valmethamide
Valnoctamida
Valnoctamide
Valnoctamidum
Valoctamidum
ATC N05CM13
CID 20140
CAS 004171135
SMILES CC[C@@H](C)[C@@H](CC)C(N)=O
Formula C8H17NO
Molweight 143.227
Atoms 10
LogP 2.2443
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 2
Transporter
AC-No.NameReferences
O15244hOCT219833842
Methylpentynol

Java required.


Information Structure
Name Methylpentynol
Synonyms
(+-)-3-Methylpent-1-yn-3-ol
2-Butanol, 2-ethynyl-
2-Ethinylbutanol-2
2-Ethynyl-2-butanol
3-Methyl-1-pentyn-2-ol
3-Methyl-pentin-(1)-ol-(3)
3-Methylpent-1-yn-3-ol
3-Methylpentin-3-ol
3-Methylpentyn-3-ol
3-Metil-pentin-3-ol
4-01-00-02242 (Beilstein Handbook Reference)
AI3-14502
AI3-37931
Allotropal
alpha-Ethyl-alpha-methylpropargyl Alcohol
Aniphor
Anti-stress
Apridol
Atemorin
Atempol
BRN 0969340
Citodorm
Comesa
Dalgol
Dormalest
Dormidin
Dormigen
Dormiphen
Dormison
Dormocit
Dormosan
EINECS 201-055-5
Ethinylmethylethylcarbinol
Ethyl Ethynyl Methyl Carbinol
Formison
Hexofen
Imnudorm
Insomnol
Macarol
Mecarol
Melpintol
Meparfynol
Mepentil
Methylethylacetylenylcarbinol
Methylethylethynylcarbinol
Methylparafynol
Methylpentinol
Methylpentynol
Methylpentynolum
Metilparafinolo
Metilpentinol
Metilpentinolo
Miramel
N-Oblivon
Noxokratin
NSC 28797
Oblevil
Oblivon
Olfine P
Olosot
Olvadon
Pentadorm
Pentinol
Pentydorm
Pentyrest
Perlopal
Riposon
Sedapercut
Seral
Sintyal
Somnesin
Sonnormon
ATC N05CM15
CID 6494
CAS 000077758
SMILES CC[C@@](C)(O)C#C
Formula C6H10O
Molweight 98.143
Atoms 7
LogP 0.7806
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 1
Transporter
AC-No.NameReferences
O15244hOCT219833842
Niaprazine

Java required.


Information Structure
Name Niaprazine
Synonyms
1709 CERM
5-23-01-00362 (Beilstein Handbook Reference)
BRN 0844157
EINECS 248-431-5
N-(3-(4-(4-Fluorophenyl)-1-piperazinyl)-1-methylpropyl)-3-pyridinecarboxamide
N-(3-(4-(p-Fluorophenyl)-1-piperazinyl)-1-methylpropyl)nicotinamide
Niaprazina
Niaprazine
Niaprazinum
Nopron
ATC N05CM16
CID 71919
CAS 027367904
SMILES C[C@@H](CCN1CCN(CC1)C2=CC=C(F)C=C2)NC(=O)C3=CN=CC=C3
Formula C20H25FN4O
Molweight 356.437
Atoms 26
LogP 2.9451
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 5
Transporter
AC-No.NameReferences
O15244hOCT219833842
Melatonin

Java required.


Information Structure
Name Melatonin
Synonyms
Melatonin
0e2b08c1-b325-45b1-8939-6f9081efdfa4
4-acetamido-4'-isothio-cyanatostilbene-2,2'-disulfonic Acid
5-22-12-00042 (Beilstein Handbook Reference)
5-Methoxy-N-acetyltryptamine
51023-76-8
73-31-4
a4039/0172195
ab00053279
ac1l1a9q
ac1q4f1w
ac1q4f1x
acetamide, N-(2-(5-methoxy-1h-indol-3-yl)ethyl)-
acetamide, N-(2-(5-methoxy-1h-indol-3-yl)ethyl)- (9ci)
acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-
acetamide, N-[2-(5-methoxy-1h-indol-3-yl)ethyl]-
acetamide, N-[2-(5-methoxy-1h-indol-3-yl)ethyl]- (9ci)
acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-
acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6ci,8ci)
acetamide, {n-[2-(5-methoxy-1h-indol-3-yl)ethyl]-}; Acetamide, {n-[2-(5-methoxyindol-3-yl)ethyl]-}; N-(2-(5-methoxy-1h-indol-3-yl)ethyl)acetamide
akos000276269
bas 01281092
bidd:er0618
bio-0635
bpbio1_000590
brd-k97530723-001-07-6
BRN 0205542
bspbio_000536
bspbio_003006
c01598
c13h16n2o2
cas-73-31-4
CCRIS 3472
chebi:16796
chembl45
chemdiv2_003916
cid896
circadin
d008550
d08170
db01065
db08189
divk1c_000353
EINECS 200-797-7
eu-0100787
hms1380b22
hms1569k18
hms1921e04
hms2089f09
hms2096k18
hms3262m16
hms501b15
hsci1_000400
hsdb 7509
i05-0076
i10-0345
idi1_000353
idi1_002631
in1244
kbio1_000353
kbio2_000665
kbio2_003233
kbio2_005801
kbio3_002226
kbiogr_000591
kbioss_000665
l001261
lopac-m-5250
lopac0_000787
ls-1623
m 5250
m-1200
m-1250
m1105
m5250_sigma
mel
mela-t
melapure
melatol
melatonex
melatonex, Melatonin
Melatonin
melatonina
melatonina (tn)
Melatonine
melovine
ml1
mls000859594
mls001055382
mls001240204
mlt
mt6
N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
n-(2-(5-methoxyindol-3-yl)ethyl)acetamide
n-acetyl-5-methoxy-tryptamine
N-Acetyl-5-methoxytryptamine
n-[2-(5-methoxy-1h-indol-3-yl)-ethyl]-acetamide
n-[2-(5-methoxy-1h-indol-3-yl)ethyl]acetamide
n-[2-(5-methoxyindol-3-yl)ethyl]acetamide
nature's Harmony
ncgc00015680-01
ncgc00015680-02
ncgc00015680-03
ncgc00015680-06
ncgc00015680-11
ncgc00015680-13
ncgc00090727-01
ncgc00090727-02
ncgc00090727-03
ncgc00090727-04
ncgc00090727-05
ncgc00090727-06
ncgc00090727-07
ncgc00090727-08
ncgc00090727-09
nci60_004378
night Rest
ninds_000353
nmr/14327425
nsc 113928
nsc113928
nsc56423
oprea1_104553
oprea1_814234
pineal Hormone
posidorm
prestwick0_000458
prestwick1_000458
prestwick2_000458
prestwick3_000458
prestwick_312
prevention 1 (melatonin) (prevention 1)
prevention 2 (melatonin)
prevention 3 (melatonin)
prevention 4 (melatonin)
prevention 5 (melatonin)
regulin
revital Melatonin
rx Balance
s1204_selleck
sdccgmls-0065812.p001
sdccgmls-0065812.p002
sits
sleep Right
smp2_000309
smr000326666
spbio_001527
spbio_002475
spectrum1500690
spectrum2_001344
spectrum3_001393
spectrum4_000066
spectrum5_001745
spectrum_000185
stk386880
tc-063565
tnp00300
unii-jl5dk93rcl
vivitas
wln: T56 Bmj D2mv1 Go1
zinc00057060
ATC N05CM17
N05CH01
CID 896
CAS 000073314
Drugbank ID DB01065
TTD Drug ID DAP000429
SMILES COC1=CC2=C(NC=C2CCNC(C)=O)C=C1
Formula C13H16N2O2
Molweight 232.278
Atoms 17
LogP 2.246
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
1A1Substrate 15616152
1A2Substrate 11317475
15616152
11703563
15626586
14616429
12906366
11452239
11317475
11270913
1B1Substrate 15616152
2C19Substrate 17003850
11270913
10877005
19AInhibitor 17342341
Phase2 interactions
NameReferences
GST 15628673
NAT 1402901,
8832214
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 3 isoform CRA_b 18289173
P14672Solute carrier family 2, facilitated glucose transporter member 4 23112392
Q00325Solute carrier family 25 member 319664004
Q86UG4Organic anion-transporting polypeptide 6A1 15628673
Dexmedetomidine

Java required.


Information Structure
Name dexmedetomidine
Synonyms
(+)-4-((s)-alpha,2,3-trimethylbenzyl)imidazole
113775-47-6
4-[(1s)-1-(2,3-dimethylphenyl)ethyl]-1h-imidazole
5-[(1s)-1-(2,3-dimethylphenyl)ethyl]-1h-imidazole
ac1nsjxt
c07450
chebi:4466
chembl778
cid5311068
d00514
dexmedetomidina
dexmedetomidine
dexmedetomidine (usan/inn)
dexmedetomidinum
mpv 1440
mpv-1440
ncgc00025347-01
precedex
precedex (tn)
tocris-2023
ATC N05CM18
CID 5311068
CAS cid5311068
Formula C13H16N2O2
Molweight 232.278
Atoms 17
LogP 2.246
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 4
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 3 isoform CRA_b 18289173
P14672Solute carrier family 2, facilitated glucose transporter member 4 23112392
Q00325Solute carrier family 25 member 319664004
Q86UG4Organic anion-transporting polypeptide 6A1 15628673
Diphenhydramin

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Information Structure
Name Diphenhydramin
Synonyms
2-(Benzhydryloxy)-N,N-dimethylethylamine
2-(Diphenylmethoxy)-N,N-dimethylethylamine
4-10-00-00125 (Beilstein Handbook Reference)
Alledryl
Allergical
alpha-(2-Dimethylaminoethoxy)diphenylmethane
Amidryl
Antistominum
Antomin
Automin
Bagodryl
Baramine
Benachlor
Benadrin
Benapon
Benodin
Benodine
Benylan
Benzantine
Benzhydramine
Benzhydraminum
Benzhydril
Benzhydroamina
beta-Dimethylamino-aethyl-benzhydryl-aether
beta-Dimethylaminoethanol Diphenylmethyl Ether
beta-Dimethylaminoethylbenzhydrylether
Betramin
BRN 1914136
CCRIS 1959
Dabylen
Debendrin
Dermistina
Dermodrin
Desentol
Diabenyl
Diabylen
Dibondrin
Difedryl
Difenhidramina
Difenhydramin
Difenidramina
Dihidral
Dimedrol Base
Diphantine
Diphenhydramin
Diphenhydramine
Diphenhydraminum
Drylistan
Dylamon
EINECS 200-396-7
Etanautine
Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-
Ethylamine, N,N-dimethyl-2-(diphenylmethoxy)-
FAR 90X2
Histaxin
HSDB 3066
Hyadrine
Ibiodral
Medidryl
Mephadryl
N-(2-(Diphenylmethoxy)ethyl)-N,N-dimethylamine
N-(Benzhydryloksy-etylo)dwumetyloamina
Nausen
Novamina
O-Benzhydryldimethylaminoethanol
PM 255
Probedryl
Rigidyl
S51
Syntedril
ATC A04AB05
N01BX06
N04AB01
N05CM20
R06AA02
S01GX16
D04AA32
CID 3100
CAS 000058731
Drugbank ID DB01075
TTD Drug ID DAP000490
SMILES CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2
Formula C17H21NO
Molweight 255.355
Atoms 19
LogP 3.3542
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
2D6Substrate Inhibitor 11270914
10824625
12678691
15718288
umm
17020955
9616188
7853212
7980647
11270914
12678691
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 3 isoform CRA_b 18289173
P14672Solute carrier family 2, facilitated glucose transporter member 4 23112392
Q00325Solute carrier family 25 member 319664004
Q86UG4Organic anion-transporting polypeptide 6A1 15628673
Extrarenal fraction 0.9
Elimination half-life 4h
Doxylamin

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Information Structure
Name Doxylamin
Synonyms
2-(alpha-(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine
2-Dimethylaminoethoxyphenylmethyl-2-picoline
5-21-03-00508 (Beilstein Handbook Reference)
BRN 0230379
Dossilamina
Doxilminio
Doxylamin
Doxylamine
Doxylaminum
EINECS 207-414-2
Ethanamine, N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)-
HSDB 5184
N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine
NCI C60684
Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl Ether
Pyridine, 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-
ATC N05CM21
R06AA09
CID 3162
CAS 000469216
Drugbank ID DB00366
TTD Drug ID DAP000859
SMILES CN(C)CCO[C@@](C)(C1=CC=CC=C1)C2=CC=CC=N2
Formula C17H22N2O
Molweight 270.369
Atoms 20
LogP 2.9233
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
3A4Inducer 8975784
3A5Inducer 8975784
3A7Inducer 8975784
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 3 isoform CRA_b 18289173
P14672Solute carrier family 2, facilitated glucose transporter member 4 23112392
Q00325Solute carrier family 25 member 319664004
Q86UG4Organic anion-transporting polypeptide 6A1 15628673
Promethazine

Java required.


Information Structure
Name Promethazine
Synonyms
(2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
10-(2-(Dimethylamino)-2-methylethyl)phenothiazine
10-(2-(Dimethylamino)propyl)phenothiazine
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-
3277 RP
4-27-00-01253 (Beilstein Handbook Reference)
A-91033
Antiallersin
Aprobit
Atosil
Avomine
BRN 0088554
Camergan
CCRIS 7056
Dimapp
Dimethylamino-isopropyl-phenthiazin
Diphergan
Diprazine
Diprozin
EINECS 200-489-2
Fargan
Fenazil
Fenetazina
Fenetazine
Hiberna
Histargan
HSDB 3173
Isophenergan
Lilly 01516
Lilly 1516
Metaryl
N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine
N-(2-Dimethylamino-2-methyl)ethylphenothiazine
N-Dimethylamino-2-methylethyl Thiodiphenylamine
NCI-C60673
NSC 30321
Pelpica
Phargan
Phenargan
Phenerzine
Phenoject-50
Phenothiazine, 10-(2-dimethylaminopropyl)-
Phensedyl
Pilothia
Pipolphene
Pro-50
Proazamine
Procit
Promacot
Promazinamide
Promergan
Promesan
Prometazina
Prometh
Promethacon
Promethazin
Promethazine
PromethazineHcl
Promethazinum
Promethegan
Promezathine
Prorex
Protazine
Provigan
Pyrethiazine
RP 3277
SKF 1498
Tanidil
Thiergan
Vallergine
WY 509
ATC D04AA10
N05CM22
R06AD02
CID 4927
CAS 000060877
Drugbank ID DB00340
TTD Drug ID DAP000334
SMILES C[C@@H](CN1C2=C(SC3=C1C=CC=C3)C=CC=C2)N(C)C
Formula C17H20N2S
Molweight 284.419
Atoms 20
LogP 4.3044
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
2B6Substrate 14515060
14515060
2C9Inhibitor 11936702
11936702
2D6Substrate Inhibitor 11936702
medicine.iupui.edu/flockhart
8946477
8946477
11936702
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 3 isoform CRA_b 18289173
P14672Solute carrier family 2, facilitated glucose transporter member 4 23112392
Q00325Solute carrier family 25 member 319664004
Q86UG4Organic anion-transporting polypeptide 6A1 15628673
Extrarenal fraction 1
Elimination half-life 12h