Compound - Results

Zopiclone

Java required.


Information Structure
Name Zopiclone
Synonyms
(+-)-Zopiclone
27267 R.P.
Amoban
Amovane
BRN 0768704
EINECS 256-138-9
Imovane
RP 27267
Zopiclona
Zopiclone
Zopiclonum
ATC N05CF01
CID 5735
CAS 043200802
Drugbank ID DB01198
TTD Drug ID DAP000427
SMILES CN1CCN(CC1)C(=O)O[C@H]2N(C(=O)C3=NC=CN=C23)C4=CC=C(Cl)C=N4
CYP interactions
NameRelationsReferences
2C8Substrate 10460808
10460808
2C9Substrate 10460808
10460808
2E1Substrate 16750462
3A4Substrate 10460808
16750462
10460808
10460808
Extrarenal fraction 0.95
Elimination half-life 4.9h
Zolpidem

Java required.


Information Structure
Name Zolpidem
Synonyms
Lorex
N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide
Zolpidem
Zolpidemum
ATC N05CF02
CID 5732
CAS 082626480
Drugbank ID DB00425
TTD Drug ID DAP000112
SMILES CN(C)C(=O)CC1=C(N=C2C=CC(C)=CN12)C3=CC=C(C)C=C3
CYP interactions
NameRelationsReferences
1A2Substrate Inhibitor 17515707
10383565
8591727
11996015
12469329
2C9Substrate Inhibitor 12469329
17515707
10383565
2C19Substrate 17515707
10383565
11996015
2D6Substrate Inhibitor 17515707
8591727
10383565
12469329
3A4Substrate 17515707
10383565
9433391
3A5Substrate medicine.iupui.edu/flockhart
3A7Substrate medicine.iupui.edu/flockhart
Extrarenal fraction 1
Elimination half-life 2.5h
Zaleplon

Java required.


Information Structure
Name Zaleplon
Synonyms
3-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilide
CL 284,846
L846
LJC 10846
N-(3-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)phenyl)-N-ethylacetamide
ZAL 846
Zaleplon
ATC N05CF03
CID 5719
CAS 151319345
Drugbank ID DB00962
TTD Drug ID DAP000266
SMILES CCN(C(C)=O)C1=CC=CC(=C1)C2=CC=NC3=C(C=NN23)C#N
Formula C17H15N5O
Molweight 305.334
Atoms 23
LogP 2.64078
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
3A4Substrate 9604298
source: www.umm.edu
12419014
3A5Substrate medicine.iupui.edu/flockhart
3A7Substrate medicine.iupui.edu/flockhart
Extrarenal fraction 1
Elimination half-life 1h
Eszopiclone

Java required.


Information Structure
Name eszopiclone
Synonyms
( )-zopiclone
(+)-(5s)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5h-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate
(+)-zopiclone
(5s)-6-(5-chloropyridin-2-yl)-7-oxo-5h,6h,7h-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
(5s)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5h-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate
(5s)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
(plus)-zopiclone
(s)-zopiclone
1-piperazinecarboxylic Acid, 4-methyl-, (5s)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5h-pyrrolo(3,4-b)pyrazin-5-yl Ester
138729-47-2
ac-5546
ac1lj6qn
ac1q3ztd
chebi:53760
chembl1522
cid969472
cpd000550478
d02624
db00402
esopiclone
estorra
estorra (tn)
eszopiclone
eszopiclone (jan/usan/inn)
eszopiclone [usan:inn]
hms3259b17
hms3264f04
hsdb 7472
ks-1055
ls-186538
ls-187032
ls-187790
lunesta
lunesta (tn)
lunivia
mls001165744
molport-002-885-823
ncgc00159515-02
sam002548982
sep-0227018
sep-0227108
sep-190
sep-225441
smr000550478
spectrum1505188
unii-uzx80k71oe
zinc19632834
zopiclone
[(7s)-6-(5-chloropyridin-2-yl)-5-oxo-7h-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
ATC N05CF04
CID 969472
CAS cid969472
Drugbank ID DB00402
TTD Drug ID DAP000933
Formula C17H15N5O
Molweight 305.334
Atoms 23
LogP 2.64078
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 4