Compound - Results

Buspirone

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Information Structure
Name Buspirone
Synonyms
5-25-10-00059 (Beilstein Handbook Reference)
8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione
Ansial
BRN 0964904
Buspirona
Buspirone
Buspironum
EINECS 253-072-2
ATC N05BE01
CID 2477
CAS 036505847
Drugbank ID DB00490
TTD Drug ID DAP000031
SMILES O=C1C[C@]2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)C4=NC=CC=N4
Formula C21H31N5O2
Molweight 385.503
Atoms 28
LogP 2.029
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 5
CYP interactions
NameRelationsReferences
2D6Substrate 15185539
15640381
3A4Substrate 15640381
12549947
11095581
14566442
9871430
9333111
15640381
17376576
3A5Substrate medicine.iupui.edu/flockhart
3A7Substrate medicine.iupui.edu/flockhart
Extrarenal fraction 1
Elimination half-life 4h