Compound - Results

Diazepam

Java required.


Information Structure
Name Diazepam
Synonyms
1-Methyl-5-phenyl-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-1-methyl-5-phenyl-
5-24-04-00300 (Beilstein Handbook Reference)
7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one (IUPAC)
7-Chloro-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepine
7-Chloro-1-methyl-5-3H-1,4-benzodiazepin-2(1H)-one
7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
7-Chloro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one
Alboral
Aliseum
Amiprol
An-Ding
Ansilive
Ansiolin
Ansiolisina
Antenex
Anxicalm
Anxionil
Apaurin
Apo-diazepam
Apozepam
Armonil
Arzepam
Assival
Atensine
Atilen
Azedipamin
Baogin
Bensedin
Benzopin
Best
Betapam
Bialzepam
Britazepam
BRN 0754371
Calmaven
Calmocitene
Calmociteno
Calmod
Calmpose
Caudel
CB 4261
CCRIS 6009
Centrazepam
Cercine
Ceregulart
Chuansuan
Condition
D-Pam
Desconet
Desloneg
Diacepan
Diaceplex
Dialag
Dialar
Diapam
Diapax
Diapine
Diaquel
Diastat
Diatran
Diazem
Diazemuls
Diazepam
Diazepam Dak
Diazepam Desitin
Diazepam Elmu
Diazepam Fabra
Diazepam Nordic
Diazepam Rectubes
Diazepam Stada
Diazepam-Eurogenerics
Diazepam-Lipuro
Diazepam-ratiopharm
Diazepamu
Diazepamum
Diazepan
Diazepan Leo
Diazepin
Diazetard
Dienpax
Dipaz
Dipezona
Disopam
Dizac
Domalium
Doval
Drenian
Ducene
Duksen
Dupin
Duxen
DZP
e-Pam
EINECS 207-122-5
Elcion CR
Eridan
Euphorin P
Eurosan
Evacalm
Faustal
Faustan
Freudal
Frustan
Gewacalm
Gihitan
Gradual
Gubex
Horizon
HSDB 3057
Iazepam
Jinpanfan
Kabivitrum
Kiatrium
Kratium
Kratium 2
LA III
LA-111
Lamra
Lembrol
Levium
Liberetas
Lizan
Lovium
Mandro
Mandro-Zep
Medipam
Mentalium
Metamidol
Methyl Diazepinone
Methyldiazepinone
Methyldiazepinone (pharmaceutical)
Metil Gobanal
Morosan
Nellium
Nerozen
Nervium
Neurolytril
Nivalen
Nixtensyn
Noan
Notense
Novazam
Novodipam
NSC 169897
NSC-77518
Ortopsique
Paceum
Paralium
Paranten
Parzam
Pax
Paxate
Paxel
Paxum
Placidox 10
Placidox 2
Placidox 5
Plidan
Pomin
Propam
Prozepam
Psychopax
Quetinil
Quiatril
Quievita
Radizepam
Relaminal
Relanium
Relax
Reliver
Renborin
Ro 5-2807
Ruhsitus
Saromet
Sedipam
Seduksen
Seduxen
Serenack
Serenamin
Serenzin
Setonil
Sibazon
Sico Relax
Simasedan
Sipam
Solis
Sonacon
Stesolid
Stesolin
Tensopam
Tranimul
Trankinon
Tranqdyn
Tranquirit
Trazepam
Umbrium
Unisedil
Usempax AP
Valaxona
Valeo
Valiquid
Valitran
Valium
Valrelease
Valuzepam
Vanconin
Vatran
Vazen
Velium
Vival
Vivol
Winii
WY-3467
Zepaxid
Zipan
ATC N05BA01
CID 3016
CAS 000439145
Drugbank ID DB00829
TTD Drug ID DNC000549
SMILES CN1C(=O)CN=C(C2=CC=CC=C2)C3=C1C=CC(Cl)=C3
Formula C16H13ClN2O
Molweight 284.74
Atoms 20
LogP 2.6544
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
1A2Substrate Inhibitor 9586962
14642738
umm
2B6Substrate umm
9633999
9586962
2C8Substrate 10771285
2C9Substrate Inhibitor 12708941
9586962
8948091
10417492
2C18Substrate 9028867
2C19Substrate Inhibitor 12708941
17375979
11038161
12846597
umm
8948091
11038161
11560871
11996015
2E1Inducer 1890612
3A4Substrate Inhibitor 9586962
10821163
12487724
11560871
12464248
9020195
11996015
medicine.iupui.edu/flockhart
umm
3A5Substrate medicine.iupui.edu/flockhart
9586962
9884317
3A7Substrate medicine.iupui.edu/flockhart
Phase2 interactions
NameReferences
NAT 11349394,
20504530,
1691454
UGT 17495417,
6800002
Extrarenal fraction 1
Elimination half-life 30h
Chlordiazepoxide

Java required.


Information Structure
Name Chlordiazepoxide
Synonyms
7-Chlor-2-methylamino-5-phenyl-3H-1,4-benzodiazepin-4-oxid
7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide
7-Chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide
7-Cloro-2-metilamino-5-fenil-3H-1,4-benzodiazepina 4-ossido
Balance
Balance (pharmaceutical)
CDO
Chlordiazepoxide
Chlordiazepoxidum
Chlordiazepoxydum
Chloridiazepide
Chlorodiazepoxide
Chlozepid
Clordiazepossido
Clordiazepoxido
Control
Decacil
Disarim
Eden
Eden-psich
EINECS 200-371-0
Elenium
Helogaphen
HSDB 3028
Ifibrium
Kalmocaps
Librelease
Librinin
Libritabs
Menrium
Mesural
Methaminodiazepoxide
Mildmen
Multum
Napoton
Psicosan
Radepur
Risolid
Silibrin
Sonimen
Tropium
Viopsicol
Zeisin
Zetran
ATC N05BA02
CID 2712
CAS 000058253
TTD Drug ID DAP000084
SMILES CNC1=NC2=C(C=C(Cl)C=C2)C(C3=CC=CC=C3)=[N+]([O-])C1
Formula C16H14ClN3O
Molweight 299.755
Atoms 21
LogP 1.2227
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2D6Substrate http://www.medicineonline.com/drugs/L/2429/LIMBITROLC-IV-chlordiazepoxide-amitript
3A4Substrate umm
Extrarenal fraction 1
Elimination half-life 15h
Medazepam

Java required.


Information Structure
Name Medazepam
Synonyms
1H-1,4-Benzodiazepine, 2,3-dihydro-7-chloro-1-methyl-5-phenyl-
2,3-Dihydro-7-chloro-1-methyl-5-phenyl-1H-1,4-benzodiazepine
5-23-09-00037 (Beilstein Handbook Reference)
7-Chloro-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepine
7-Chloro-2,3-dihydro-1-methyl-5-phenyl-3H-1,4-benzodiazepine
Ansilan
BRN 0407983
EINECS 220-783-4
Medazepam
Medazepamum
Resmit
Rudotel
ATC N05BA03
CID 4041
CAS 002898126
SMILES CN1CCN=C(C2=CC=CC=C2)C3=C1C=CC(Cl)=C3
Formula C16H15ClN2
Molweight 270.757
Atoms 19
LogP 3.1278
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
2C19Substrate 18175099
2E1Inhibitor 9574817
3A4Substrate 18175099
Oxazepam

Java required.


Information Structure
Name Oxazepam
Synonyms
(+-)-Oxazepam
(RS)-Oxazepam
1,3-Dihydro-7-chloro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Abboxapam
Adumbran
Ansioxacepam
Anxiolit
Anxiolit Retard
Aplakil
Astress
Azutranquil
Bonare
CB 8092
CCRIS 488
DRG-0057
Drimuel
Droxacepam
Durazepam
EINECS 210-076-9
Enidrel
Enidrel (VAN)
Hi-Long
HSDB 3140
Isodin
Limbial
Murelax
N-Desmethyltemazepam
Nesontil
Noctazepam
Nortemazepam
Nozepam
NSC 169448
Ossazepam
Oxazepam
Oxazepamum
Pacienx
Praxiten
Propax
Psicopax
Psiquiwas
Quilibrex
Ro 5-6789
Rondar
Sedigoa
Serax
Serenal
Serenid
Serepax
Seresta
Serpax
Sigacalm
Sobril
Tarchomin
Tazepam
Tranquo-buscopan-wirkstoff
Uskan
Vaben
Wy 3498
WY-3498
Z 10 Tr
Z10-TR
Zaxopam
ATC N05BA04
CID 4616
CAS 000604751
Drugbank ID DB00842
TTD Drug ID DAP000243
SMILES O[C@@H]1N=C(C2=CC=CC=C2)C3=C(NC1=O)C=CC(Cl)=C3
Formula C15H11ClN2O2
Molweight 286.713
Atoms 20
LogP 2.0215
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
3A4Substrate 10659949
10935727
3A5Substrate 10659949
3A7Substrate 10659949
3A43Substrate 10659949
Phase2 interactions
NameReferences
UGT 15044558,
19916996
Transporter
AC-No.NameReferences
P78381Solute carrier family 35 member A2 15044558
Extrarenal fraction 1
Elimination half-life 10h
Potassium Clorazepate

Java required.


Information Structure
Name Potassium clorazepate
Synonyms
Potassium Clorazepate
ATC N05BA05
CAS x024
SMILES OC(O)[C@@H]1N=C(C2=CC=CC=C2)C3=C(NC1=O)C=CC(Cl)=C3
Formula C15H11ClN2O2
Molweight 286.713
Atoms 20
LogP 2.0215
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 4
Transporter
AC-No.NameReferences
P78381Solute carrier family 35 member A2 15044558
Lorazepam

Java required.


Information Structure
Name Lorazepam
Synonyms
5-25-02-00248 (Beilstein Handbook Reference)
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one
7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
Almazine
Anxiedin
Anxira
Anzepam
Aplacasse
Aplacassee
Apo-Lorazepam
Aripax
Ativan
Azurogen
Bonatranquan
Bonton
BRN 0759084
Delormetazepam
Demethyllormetazepam
Donix
Duralozam
Efasedan
EINECS 212-687-6
Emotion
Emotival
Equitam
Idalprem
Kalmalin
Larpose
Laubeel
Lomesta
Lopam
Lorabenz
Lorafen
Loram
Lorans
Lorapam
Lorat
Lorax
Lorazene
Lorazep
Lorazepam
Lorazepam Fabra
Lorazepam Genericon
Lorazepam Lannacher
Lorazepam Medical
Lorazepam-Efeka
Lorazepamum
Lorazepan Chobet
Lorazepan Richet
Lorazin
Lorazon
Lorenin
Loridem
Lorivan
Lorsedal
Lorzem
Lozepam
Max Pax
Merlit
Nervistop L
Nervistopl
NIC
Norlormetazepam
Novhepar
Novolorazem
NSC 289758
Nu Loraz
o-Chlorooxazepam
o-Chloroxazepam
Orfidal
Punktyl
Quait
Renaquil
Rocosgen
Sedatival
Sedizepan
Sidenar
Silence
Sinestron
Stapam
Tavor
Temesta
Titus
Tolid
Tranqipam
Trapax
Upan
Vigiten
WY 4036
Wypax
ATC N05BA06
CID 3958
CAS 000846491
Drugbank ID DB00186
TTD Drug ID DAP000237
SMILES O[C@H]1N=C(C2=CC=CC=C2Cl)C3=C(NC1=O)C=CC(Cl)=C3
Formula C15H10Cl2N2O2
Molweight 321.158
Atoms 21
LogP 2.6749
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 4
Transporter
AC-No.NameReferences
P78381Solute carrier family 35 member A2 15044558
Extrarenal fraction 1
Elimination half-life 15h
Adinazolam

Java required.


Information Structure
Name Adinazolam
Synonyms
8-Chloro-1-((dimethylamino)methyl)-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine
Adinazolam
Adinazolamum
U 41,123
U 41123
ATC N05BA07
CID 37632
CAS 037115325
Drugbank ID DB00546
TTD Drug ID DAP001251
SMILES CN(C)CC1=NN=C2CN=C(C3=CC=CC=C3)C4=C(C=CC(Cl)=C4)N12
Formula C19H18ClN5
Molweight 351.833
Atoms 25
LogP 2.7689
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
2C19Substrate 9600717
9600717
3A4Substrate 9600717
9600717
Transporter
AC-No.NameReferences
P78381Solute carrier family 35 member A2 15044558
Bromazepam

Java required.


Information Structure
Name Bromazepam
Synonyms
1,3-Dihydro-7-bromo-5-(2-pyridyl)-2H-1,4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-bromo-5-(2-pyridyl)-
5-26-05-00078 (Beilstein Handbook Reference)
7-Bromo-1,3-dihydro-5-(2-pyridyl)-2H-1,4-benzdiazepin-2-one
7-Bromo-1,3-dihydro-5-(2-pyridyl)-2H-1,4-benzodiazepin-2-one
7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiazepin-2(1H)-one
BRN 0618645
Bromazepam
Bromazepamum
Compedium
Compendium
Creosedin
EINECS 217-322-4
KL-001
LA Xvii
Lectopam
Lekotam
Lexaurin
Lexilium
Lexomil
Lexotan
Lexotanil
NSC 140669
Ro 4-9253
Ro 5-3350
ATC N05BA08
CID 2441
CAS 001812302
Drugbank ID DB01558
TTD Drug ID DAP001035
SMILES BrC1=CC2=C(NC(=O)CN=C2C3=CC=CC=N3)C=C1
Formula C14H10BrN3O
Molweight 316.153
Atoms 19
LogP 2.2072
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
1A2Substrate 9435993
2C19Substrate 9435993
2E1Inhibitor umm
3A4Substrate umm
Transporter
AC-No.NameReferences
P78381Solute carrier family 35 member A2 15044558
Extrarenal fraction 1
Elimination half-life 16h
Clobazam

Java required.


Information Structure
Name Clobazam
Synonyms
1-Phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine
5-24-08-00034 (Beilstein Handbook Reference)
7-Chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2,4-(3H,5H)-dione
BRN 0758410
CCRIS 7506
Chlorepin
Clobazam
Clobazamum
Clorepin
EINECS 244-908-7
Frisium
H 4723
H-4723
HR 376
LM-2717
NSC 336279
RU-4723
Urbanyl
ATC N05BA09
CID 2789
CAS 022316478
Drugbank ID DB00349
TTD Drug ID DAP000672
SMILES CN1C(=O)CC(=O)N(C2=CC=CC=C2)C3=C1C=CC(Cl)=C3
Formula C16H13ClN2O2
Molweight 300.74
Atoms 21
LogP 3.5012
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
2B6Substrate 15483195
2C18Substrate 15483195
2C19Substrate 12451290
15533655
15483195
14729419
3A4Substrate umm
15483195
Transporter
AC-No.NameReferences
P78381Solute carrier family 35 member A2 15044558
Extrarenal fraction 1
Elimination half-life 18h
Ketazolam

Java required.


Information Structure
Name Ketazolam
Synonyms
11-Chloro-8,12b-dihydro-2,8-dimethyl-12b-phenyl-4H-(1,3)-oxazino(3,2-d)(1,4)benzodiazepine-4,7(6H)dione
Ansieten
Anxon
EINECS 248-346-3
Ketazolam
Ketazolamum
NSC 338158
U 28774
U-28,774
Unakalm
ATC N05BA10
CID 33746
CAS 027223354
Drugbank ID DB01587
SMILES CN1C(=O)CN2C(=O)C=C(C)O[C@]2(C3=CC=CC=C3)C4=C1C=CC(Cl)=C4
Formula C20H17ClN2O3
Molweight 368.814
Atoms 26
LogP 3.283
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 3
Transporter
AC-No.NameReferences
P78381Solute carrier family 35 member A2 15044558
Extrarenal fraction 1
Elimination half-life 2h
Prazepam

Java required.


Information Structure
Name Prazepam
Synonyms
5-24-04-00304 (Beilstein Handbook Reference)
7-Chloro-1-(cyclopropylmethyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-1-cyclopropylmethyl-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one
BRN 0895797
Centrax
Demetrin
EINECS 220-975-8
K-373
Lysanxia
NSC 277179
Prazepam
Prazepamum
Trepidan
Verstran
W 4020
ATC N05BA11
CID 4890
CAS 002955386
Drugbank ID DB01588
TTD Drug ID DAP000689
SMILES ClC1=CC2=C(C=C1)N(C[C@H]3CC3)C(=O)CN=C2C4=CC=CC=C4
Formula C19H17ClN2O
Molweight 324.804
Atoms 23
LogP 3.4346
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
3A4Substrate umm
Transporter
AC-No.NameReferences
P78381Solute carrier family 35 member A2 15044558
Extrarenal fraction 1
Elimination half-life 60h
Alprazolam

Java required.


Information Structure
Name Alprazolam
Synonyms
8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine
Alcelam
Algad
Alpaz
Alplax
Alpram
Alprax
Alprazolam
Alprazolamum
Alpronax
Alprox
Alzam
Alzolam
Alzon
Anpress
Apo-Alpraz
Azor
Bestrol
BRN 1223125
Cassadan
Constan
D 65MT
EINECS 249-349-2
Esparon
Frontal
Gen-Alprazolan
Helex
Intensol
Ksalol
Mialin
Neurol
Novo-Alprazol
Nu-Alpraz
Panix
Pharnax
Prazam
Prazolan
Prinox
Ralozam
Relaxol
Restyl
Solanax
Tafil
Tensivan
Trankimazin
Tranquinal
Tricalma
TUS-1
U 31889
Unilan
Valeans
Xanagis
Xanax
Xanax XR
Xanor
Zacetin
Zanapam
Zaxan
Zenax
Zolan
Zolarem
Zoldac
Zoldax
Zotran
ATC N05BA12
CID 2118
CAS 028981977
Drugbank ID DB00404
TTD Drug ID DAP000239
SMILES CC1=NN=C2CN=C(C3=CC=CC=C3)C4=C(C=CC(Cl)=C4)N12
Formula C17H13ClN4
Molweight 308.765
Atoms 22
LogP 3.0157
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
3A4Substrate 10548453
10923859
10709776
11304902
12196913
15856409
15806426
10770452
10634135
10548453
8851634
3A5Substrate medicine.iupui.edu/flockhart
15903124
3A7Substrate medicine.iupui.edu/flockhart
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323
Extrarenal fraction 0.7
Elimination half-life 13h
Halazepam

Java required.


Information Structure
Name Halazepam
Synonyms
5-24-04-00303 (Beilstein Handbook Reference)
7-Chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one
BRN 0898553
EINECS 245-425-4
Halazepam
Halazepamum
Paxipam
Sch 12041
Schering 12041
ATC N05BA13
CID 31640
CAS 023092173
Drugbank ID DB00801
TTD Drug ID DAP000679
SMILES FC(F)(F)CN1C(=O)CN=C(C2=CC=CC=C2)C3=C1C=CC(Cl)=C3
Formula C17H12ClF3N2O
Molweight 352.738
Atoms 24
LogP 3.5869
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 5
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323
Pinazepam

Java required.


Information Structure
Name Pinazepam
Synonyms
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-1-(2-propynyl)-
5-24-04-00304 (Beilstein Handbook Reference)
7-Chloro-1,3-dihydro-5-phenyl-1-(2-propynyl)-2H-1,4-benzodiazepin-2-one
7-Chloro-1-propargyl-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-2,3-dihydro-5-phenyl-1-propargyl-1H-1,4-benzodiazepin-2-one
BRN 0758533
EINECS 257-934-9
Pinazepam
Pinazepamum
Z-905
ZAMI 905
ATC N05BA14
CID 40391
CAS 052463839
SMILES ClC1=CC2=C(C=C1)N(CC#C)C(=O)CN=C2C3=CC=CC=C3
Formula C18H13ClN2O
Molweight 308.762
Atoms 22
LogP 2.6578
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 2
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323
Camazepam

Java required.


Information Structure
Name Camazepam
Synonyms
3-N,N-Dimethylcarbamoyloxy-7-chloro-5-phenyl-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
5-25-02-00244 (Beilstein Handbook Reference)
7-Chloro-1,3-dihydro-3-(N,N-dimethylcarbamoyl)-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-1,4-benzodiazepin-2-one Dimethylcarbamate
Albego
B 5333
BRN 0715180
Camazepam
Camazepamum
EINECS 252-866-6
SB 5833
ATC N05BA15
CID 37367
CAS 036104800
SMILES CN(C)C(=O)O[C@@H]1N=C(C2=CC=CC=C2)C3=C(C=CC(Cl)=C3)N(C)C1=O
Formula C19H18ClN3O3
Molweight 371.818
Atoms 26
LogP 2.6787
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 4
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323
Nordazepam

Java required.


Information Structure
Name Nordazepam
Synonyms
1-Demethyldiazepam
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-
5-24-04-00291 (Beilstein Handbook Reference)
7-Chlor-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-on
7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
A 101
A101
BRN 0751823
Calmday
Chlordesmethyldiazepam
Dealkylprazepam
Demadar
Desalkylprazepam
Desmethyldiazepam
DMDZ
EINECS 214-123-4
Lomax
Madar
N-Demethyldiazepam
N-Deoxydemoxapam
N-Deoxydemoxepam
N-Descyclopropylmethylprazepam
N-Desmethyldiazepam
N1-Desmethyldiazepam
NDD
NDZ
Nordazepam
Nordazepamum
Nordiazepam
Norprazepam
NSC 46078
Ro 5-2180
Sopax
Stilny
Vegesan
ATC N05BA16
CID 2997
CAS 001088115
SMILES ClC1=CC2=C(NC(=O)CN=C2C3=CC=CC=C3)C=C1
Formula C15H11ClN2O
Molweight 270.714
Atoms 19
LogP 2.7031
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2C19Substrate 8948091
8904619
10613621
3A4Substrate 10359672
8948091
8948091
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323
Extrarenal fraction 1
Elimination half-life 80h
Fludiazepam

Java required.


Information Structure
Name Fludiazepam
Synonyms
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-fluorophenyl)-1,3-dihydro-1-methyl-
5-24-04-00320 (Beilstein Handbook Reference)
7-Chloro-5-(2-fluorophenyl)-1-methyl-1H-1,4-benzodiazepin-2(3H)-one
BRN 0686115
Erispan
Fludiazepam
Fludiazepamum
ID 540
Ro 5-3438
ATC N05BA17
CID 3369
CAS 003900310
Drugbank ID DB01567
TTD Drug ID DAP000934
SMILES CN1C(=O)CN=C(C2=C(F)C=CC=C2)C3=C1C=CC(Cl)=C3
Formula C16H12ClFN2O
Molweight 302.731
Atoms 21
LogP 2.7935
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 3
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323
Ethyl Loflazepate

Java required.


Information Structure
Name Ethyl loflazepate
Synonyms
5-25-08-00124 (Beilstein Handbook Reference)
BRN 0765264
CM 6912
EINECS 249-489-4
Ethyl 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepine-3-carboxylate
Ethyl Fluclozepate
Ethyl Loflazepate
Ethylis Loflazepas
Loflazepate Dethyle
Loflazepato De Etilo
Loflazepic Acid, Ethyl Ester
Victan
ATC N05BA18
CID 3299
CAS 029177842
SMILES CCOC(=O)[C@H]1N=C(C2=C(F)C=CC=C2)C3=C(NC1=O)C=CC(Cl)=C3
Formula C18H14ClFN2O3
Molweight 360.767
Atoms 25
LogP 2.7739
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 6
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323
Etizolam

Java required.


Information Structure
Name Etizolam
Synonyms
6-(o-Chlorophenyl)-8-ethyl-1-methyl-4H-s-triazolo(3,4-c)thieno(2,3-e)(1,4)-diazepine
6-(o-Chlorphenyl)-8-aethyl-1-methyl-4H-s-triazolo(3,4-c)thieno(2,3-e)(1,4)diazepin
6H-Thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine, 4-(2-chlorophenyl)-2-ethyl-9-methyl-
8-Ethyl-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo(3,4c)thieno(2,3e)-1,4-diazepine
AHR 3219
BRN 0572740
Depas
Etizolam
Etizolamum
Y-7131
ATC N05BA19
CID 3307
CAS 040054691
SMILES CCC1=CC2=C(S1)N3C(C)=NN=C3CN=C2C4=C(Cl)C=CC=C4
Formula C17H15ClN4S
Molweight 342.846
Atoms 23
LogP 3.6396
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2C19Substrate 17635335
3A4Substrate 15232663
15232663
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323
Clotiazepam

Java required.


Information Structure
Name Clotiazepam
Synonyms
5-(2-Chlorophenyl)-7-ethyl-1-methyl-1,3-dihydro-2H-thieno(2,3-e)(1,4)diazepin-2-one
5-(o-Chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-2H-thieno(2,3-e)-1,4-diazepin-2-one
BRN 0623332
Clotiazepam
Clotiazepamum
EINECS 251-627-3
Rise
Trecalmo
Y 6047
ATC N05BA21
CID 2811
CAS 033671464
Drugbank ID DB01559
TTD Drug ID DAP000932
SMILES CCC1=CC2=C(S1)N(C)C(=O)CN=C2C3=C(Cl)C=CC=C3
Formula C16H15ClN2OS
Molweight 318.821
Atoms 21
LogP 3.2783
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
2B6Substrate 16141545
2C18Substrate 16141545
2C19Substrate 16141545
3A4Substrate Inhibitor 16141545
16141545
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323
Cloxazolam

Java required.


Information Structure
Name Cloxazolam
Synonyms
BRN 0569691
Cloxazolam
Cloxazolamum
Cloxazolazepam
CS 370
Enadel
MT 14-411
Olcadil
Sepazon
ATC N05BA22
CID 2816
CAS 024166130
SMILES ClC1=CC2=C(NC(=O)CN3CCO[C@]23C4=C(Cl)C=CC=C4)C=C1
Formula C17H14Cl2N2O2
Molweight 349.211
Atoms 23
LogP 3.5547
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 4
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323
Extrarenal fraction 1
Elimination half-life 50h
Tofisopam

Java required.


Information Structure
Name Tofisopam
Synonyms
1-(3,4-Dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
Egyt 341
EINECS 244-922-3
Grandaxin
Tofisopam
Tofisopamum
ATC N05BA23
CID 5502
CAS 022345477
SMILES CC[C@@H]1C(C)=NN=C(C2=CC(OC)=C(OC)C=C2)C3=C1C=C(OC)C(OC)=C3
Formula C22H26N2O4
Molweight 382.453
Atoms 28
LogP 3.3127
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
3A4Inhibitor 16711396
16711396
Transporter
AC-No.NameReferences
Q12908Na(+)-dependent ileal bile acid transporter12401323