Compound - Results

Haloperidol

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Information Structure
Name Haloperidol
Synonyms
1-(3-p-Fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine
1-Butanone, 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-
4-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone
4-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-4-fluorobutyrophenone
4-(4-Hydroxy-4-chloro-4-phenylpiperidino)-4-fluorobutyrophenone
4-Fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone
4-Fluoro-4-(4-hydroxy-4-(4-chlorophenyl)piperidino)butyrophenone
4-Fluoro-4-(4-hydroxy-4-p-chlorophenylpiperidino)butyrophenone
5-21-02-00377 (Beilstein Handbook Reference)
Aldo
Aloperidin
Aloperidol
Aloperidolo
BRN 0331267
Brotopon
Butyrophenone, 4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4-fluoro-
Butyrophenone, 4-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-
CCRIS 1630
Dozic
Einalon S
EINECS 200-155-6
Eukystol
Fortunan
Galoperidol
gamma-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-p-fluorbutyrophenone
gamma-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-p-fluorobutyrophenone
Haldol
Halojust
Halopal
Haloperidol
Haloperidolum
Halopoidol
HSDB 3093
Keselan
Lealgin Compositum
Linton
McN-JR-1625
Mixidol
NSC 170973
Peluces
Pernox
R 1625
Serenace
Serenase
Serenelfi
Sernas
Sernel
Ulcolind
Uliolind
Vesalium
ATC N05AD01
CID 3559
CAS 000052868
Drugbank ID DB00502
TTD Drug ID DAP000313
SMILES O[C@@]1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C=C3
Formula C21H23ClFNO2
Molweight 375.864
Atoms 26
LogP 4.3635
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
1A1Substrate 11717183
1A2Substrate
2C9Substrate 11717183
2C19Substrate 11717183
2D6Substrate Inhibitor Inducer 9681669
15048614
medicine.iupui.edu/flockhart
1412613
10688273
11717183
10460810
15048614
9681669
3A4Substrate Inhibitor 9431831
umm
10628896
12584149
11717183
11133003
9431831
3A5Substrate medicine.iupui.edu/flockhart
12584149
11717183
3A7Substrate medicine.iupui.edu/flockhart
Phase2 interactions
NameReferences
NAT 10494878
Transporter
AC-No.NameReferences
Q9P2U7Vesicular glutamate transporter 1 18155072
Extrarenal fraction 1
Elimination half-life 20h
Trifluperidol

Java required.


Information Structure
Name Trifluperidol
Synonyms
1-Butanone, 1-(4-fluorophenyl)-4-(4-hydroxy-4-(3-(trifluoromethyl)phenyl)-1-piperidinyl)-
4-Fluoro-4,4-idrossi-4-(m-trifluorometil-fenil)-piperidino-butirrofenone
4-Fluoro-4-(4-hydroxy-4-(alpha,alpha,alpha-trifluoro-m-tolyl)piperidino)butyrophenone
5-21-02-00406 (Beilstein Handbook Reference)
BRN 1556208
Flumoperone
McN-JR-2498
NSC 170978
P 459
Psicoperidol
Psicoperidol-R
Psychoperidol
R-2498
Trifluperidol
Trifluperidolo
Trifluperidolum
Triperidol
Trisedil
Trisedyl
ATC N05AD02
CID 11647992
CAS 000749133
SMILES O[C@@]1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC(=CC=C3)C(F)(F)F
Formula C22H24ClF4NO2
Molweight 445.878
Atoms 30
LogP 5.5309
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 7
CYP interactions
NameRelationsReferences
2D6Substrate 11996015
Transporter
AC-No.NameReferences
Q9P2U7Vesicular glutamate transporter 1 18155072
Melperone

Java required.


Information Structure
Name Melperone
Synonyms
FG 5111
Melperona
Melperone
Melperonum
Metylperon
Metylperonum
ATC N05AD03
CID 15387
CAS 003575802
SMILES C[C@H]1CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1
Formula C16H22FNO
Molweight 263.35
Atoms 19
LogP 3.4584
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2D6Inhibitor 12649767
12649767
Transporter
AC-No.NameReferences
Q9P2U7Vesicular glutamate transporter 1 18155072
Moperone

Java required.


Information Structure
Name Moperone
Synonyms
EINECS 213-887-6
Meperon
Methylperidol
Moperona
Moperone
Moperonum
Mopiperone
omega-(4-Hydroxy-4-p-tolylpiperidino)-p-fluorobutyrophenone
p-Fluoro-4-(4-hydroxy-4-p-methylphenylpiperidino)butyrophenone
p-Fluoro-4-(4-hydroxy-4-p-tolylpiperidino)butyrophenone
ATC N05AD04
CID 4249
CAS 001050799
SMILES CC1=CC=C(C=C1)[C@@]2(O)CCN(CCCC(=O)C3=CC=C(F)C=C3)CC2
Formula C22H26FNO2
Molweight 355.446
Atoms 26
LogP 4.0185
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 4
Transporter
AC-No.NameReferences
Q9P2U7Vesicular glutamate transporter 1 18155072
Pipamperone

Java required.


Information Structure
Name Pipamperone
Synonyms
1-(3-(p-Fluorobenzoyl)propyl)-(1,4-bipiperidine)-4-carboxamide
4-Fluoro-4-(4-N-piperidino-4-carbamidopiperidino)butyrophenone
5-22-13-00536 (Beilstein Handbook Reference)
BRN 0496532
Dipiperal
Dipiperon
Dipiperone
Floropipamide
Isonipacotamide, 1-(3-(p-fluorobenzoyl)propyl)-4-piperidino-
McN-JR-3345
p-Fluoro-gamma-(4-piperidino-4-carbamoylpiperidino)butyrophenone
Pipamperona
Pipamperone
Pipamperonum
Piperonil
Piperonyl
R 3345
ATC N05AD05
CID 4830
CAS 001893330
SMILES NC(=O)[C@]1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)N3CCCCC3
Formula C21H30FN3O2
Molweight 375.48
Atoms 27
LogP 3.1705
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
1A1Inducer 9233375
1A2Inducer 9233375
Phase2 interactions
NameReferences
GST 9566212
SUL 8870951
Transporter
AC-No.NameReferences
Q9P2U7Vesicular glutamate transporter 1 18155072
Bromperidol

Java required.


Information Structure
Name Bromperidol
Synonyms
4-(4-(4-Bromophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone
4-(4-(4-Bromophenyl)-4-hydroxypiperidino)-4-fluorobutyrophenone
4-(4-(p-Bromophenyl)-4-hydroxypiperidino)-4-fluorobutyrophenone
4-(4-(p-Bromophenyl)-4-hydroxypiperidinol)-4-fluorobutyrophenone
5-21-02-00382 (Beilstein Handbook Reference)
BRN 1552256
Bromoperidol
Bromperidol
Bromperidolum
EINECS 233-943-3
R 11333
ATC N05AD06
CID 2448
CAS 010457906
SMILES O[C@]1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Br)C=C3
Formula C21H23BrFNO2
Molweight 420.315
Atoms 26
LogP 4.4726
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
3A4Substrate 11133003
9592806
10463320
10752674
10752674
Transporter
AC-No.NameReferences
Q9P2U7Vesicular glutamate transporter 1 18155072
Benperidol

Java required.


Information Structure
Name Benperidol
Synonyms
1-(1-(3-(p-Fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinone
2H-Benzimidazol-2-one, 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl)-1,3-dihydro-
4-Fluor-4-(4-(2-oxo-1-benzimidazolinyl)piperidino)butyrophenon
5-24-02-00375 (Beilstein Handbook Reference)
8089 C. B.
8089 C.B.
Anquil
Anquil (VAN)
Benperidol
Benperidolo
Benperidolum
Benzoperidol
BRN 0900981
Concilium
EINECS 218-172-2
Frenactil
Frenactyl
Glianimon
Glianimon Mite
McN-JR-4584
NSC 170982
R 4584
R-4584
ATC N05AD07
CID 16363
CAS 002062842
SMILES FC1=CC=C(C=C1)C(=O)CCCN2CC[C@@H](CC2)N3C(=O)NC4=CC=CC=C34
Formula C22H24FN3O2
Molweight 381.443
Atoms 28
LogP 3.7066
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 5
Transporter
AC-No.NameReferences
Q9P2U7Vesicular glutamate transporter 1 18155072
Droperidol

Java required.


Information Structure
Name Droperidol
Synonyms
1-(1-(3-(p-Fluorobenzoyl)propyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone
1-(1-(4-(p-Fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridyl)-2-benzimidazolinone
5-24-02-00388 (Beilstein Handbook Reference)
BRN 0579168
Dehydrobenzoperidol
Dehydrobenzperidol
Deidrobenzperidolo
DHBP
Dridol
Droleptan
Droperidol
Droperidolo
Droperidolum
EINECS 208-957-8
Halkan
HSDB 3320
Inapsin
Inapsine
Inopsin
McN-JR-4749
NSC 169874
Properidol
R 4749
R-4749
R4749
Sintodril
Sintosian
Vetkalm
ATC N01AX01
N05AD08
CID 3168
CAS 000548732
Drugbank ID DB00450
TTD Drug ID DAP000412
SMILES FC1=CC=C(C=C1)C(=O)CCCN2CCC(=CC2)N3C(=O)NC4=C3C=CC=C4
Formula C22H22FN3O2
Molweight 379.427
Atoms 28
LogP 3.6163
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 5
Transporter
AC-No.NameReferences
Q9P2U7Vesicular glutamate transporter 1 18155072
Extrarenal fraction 1
Elimination half-life 2.2h
Fluanisone

Java required.


Information Structure
Name Fluanisone
Synonyms
2028 MD
4-(4-(o-Methoxyphenyl)-1-piperazinyl)-p-fluorobutyrophenone
4-Fluoro-4-(4-(o-methoxyphenyl)-1-piperazinyl)butyrophenone
5-23-02-00213 (Beilstein Handbook Reference)
Anti-Pica
BRN 0707524
EINECS 216-038-8
Fluanison
Fluanisona
Fluanisone
Fluanisonum
Haloanison
Haloanisone
MD 2028
Metorin
NSC 170977
R 2028
R 2167
Sedalande
ATC N05AD09
CID 15139
CAS 001480199
SMILES COC1=C(C=CC=C1)N2CCN(CCCC(=O)C3=CC=C(F)C=C3)CC2
Formula C21H25FN2O2
Molweight 356.434
Atoms 26
LogP 3.6223
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 4
Transporter
AC-No.NameReferences
Q9P2U7Vesicular glutamate transporter 1 18155072