Compound - Results

Chlorpromazine

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Information Structure
Name Chlorpromazine
Synonyms
2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine
2-Chloropromazine
2-Cloro-10 (3-dimetilaminopropil)fenotiazina
4560 R.P.
Aminazin
Aminazine
Ampliactil
BC 135
CCRIS 3711
Chlor-Promanyl
Chlorderazin
Chloro-3 (dimethylamino-3 Propyl)-10 Phenothiazine
Chloropromazine
Chlorpromados
Chlorpromazin
Chlorpromazine
Chlorpromazinum
Clorpromazina
Contomin
CPZ
EINECS 200-045-8
Elmarin
Esmind
Fenactil
Fenaktyl
Fraction AB
HL 5746
HSDB 3033
Largactil
Largactilothiazine
Largactyl
Megaphen
N-(3-Dimethylaminopropyl)-3-chlorophenothiazine
Novomazina
NSC 167745
Phenactyl
Proma
Promactil
Promazil
Propaphenin
Prozil
Psychozine
Sanopron
SKF 2601-A
Thorazine
Thorazine Suppositories
Torazina
Wintermin
ATC N05AA01
CID 2726
CAS 000050533
Drugbank ID DB00477
TTD Drug ID DAP000374
SMILES CN(C)CCCN1C2=C(SC3=C1C=C(Cl)C=C3)C=CC=C2
Formula C17H19ClN2S
Molweight 318.864
Atoms 21
LogP 4.9594
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A1Inducer 16611858
1A2Substrate Inhibitor Inducer 10901285
16611858
20615392
17611010
11985335
2B6Inducer 10608490
2D6Substrate Inhibitor 10460810
8739822
16910628
9169082
11477317
10688273
7699230
8100507
9811161
6135583
10901285
10460810
11725960
2E1Inhibitor umm
9574817
3A4Substrate Inducer umm
11996015
10608490
3A5Inducer 10608490
Transporter
AC-No.NameReferences
Q86UG4Solute carrier organic anion transporter family member 6A1 11111222
Q9Y345Sodium- and chloride-dependent glycine transporter 215374578
Extrarenal fraction 1
Elimination half-life 30h
Levomepromazine

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Information Structure
Name Levomepromazine
Synonyms
(-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine
10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,beta-trimethyl-, (R)-
2-Methoxytrimeprazine
7044 R.P.
Arc-VI-C-5
Bayer 1213
CL 36467
CL 39743
CL 53212
Dedoran
EINECS 200-495-5
Hirnamin
Hirnamine
Levomeprazine
Levomepromazin
Levomepromazina
Levomepromazine
Levomepromazinum
Levopromazine
Levopromazioni
Levoprome
Levopromethazine
Levotomin
Mepromazine
Methotrimeprazine
Methoxytrimeprazine
Milezin
Minozinan
Neozine
Neurocil
Nirnamine
Nirvan
Nocinan
Nomizan
Nozinan
Nozinane
NSC 226516
RP 7044
Sinogan
Sinogan-debil
SK&F 5116
SKF 5116
Tisercin
Veractil
ATC N05AA02
CID 72287
CAS 000060991
Drugbank ID DB01403
SMILES COC1=CC2=C(SC3=C(C=CC=C3)N2C[C@H](C)CN(C)C)C=C1
Formula C19H24N2OS
Molweight 328.472
Atoms 23
LogP 4.5606
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
2D6Substrate Inhibitor 10954064
11888334
10954064
2E1Inhibitor 11985335
Transporter
AC-No.NameReferences
Q86UG4Solute carrier organic anion transporter family member 6A1 11111222
Q9Y345Sodium- and chloride-dependent glycine transporter 215374578
Extrarenal fraction 1
Elimination half-life 50h
Promazine

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Information Structure
Name Promazine
Synonyms
10-(3-(Dimethylamino)propyl)phenothiazine
10H-Phenothiazine-10-propanamine, N,N-dimethyl-
3276 R. P.
A 145
Ampazine
Berophen
EINECS 200-382-0
Esparin
HSDB 3172
Liranol
N-(3-Dimethylaminopropyl)phenothiazine
N-Dimethylamino-1-methylethyl Thiodiphenylamine
Neo-Hibernex
NSC 31447
Prazin
Prazine
Promazin
Promazina
Promazine
Promazinum
Promwill
Propazinum
Protactyl
Romtiazin
RP 3276
Sinophenin
Tomil
Verophen
WY 1094
ATC N05AA03
CID 4926
CAS 000058402
Drugbank ID DB00420
TTD Drug ID DAP000430
SMILES CN(C)CCCN1C2=C(SC3=C1C=CC=C3)C=CC=C2
Formula C17H20N2S
Molweight 284.419
Atoms 20
LogP 4.306
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Substrate 12721102
12721102
2C19Substrate 12721102
12721102
3A4Substrate 12721102
Transporter
AC-No.NameReferences
Q86UG4Solute carrier organic anion transporter family member 6A1 11111222
Q9Y345Sodium- and chloride-dependent glycine transporter 215374578
Acepromazine

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Information Structure
Name Acepromazine
Synonyms
1-(10-(3-(Dimethylamino)propyl)-10H-phenothiazin-2-yl)ethanone
10-(3-Dimethylaminopropyl)phenothiazin-3-yl Methyl Ketone
10-(3-Dimethylaminopropyl)phenothiazine-3-ethylone
1522 CB
2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine
Acepromazina
Acepromazine
Acepromazinum
Acetopromazine
Acetylpromazine
Anergan
Atsetozin
AY-57,062
Azepromazine
EINECS 200-496-0
Notensil
Plegicil
Plivafen
Promazine, Acetyl-
SV-1522
Vetranquil
WY-1172
ATC N05AA04
CID 6077
CAS 000061007
Drugbank ID DB00577
SMILES CN(C)CCCN1C2=C(SC3=C1C=C(C=C3)C(C)=O)C=CC=C2
Formula C19H22N2OS
Molweight 326.456
Atoms 23
LogP 4.5086
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 2
Transporter
AC-No.NameReferences
Q86UG4Solute carrier organic anion transporter family member 6A1 11111222
Q9Y345Sodium- and chloride-dependent glycine transporter 215374578
Triflupromazin

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Information Structure
Name Triflupromazin
Synonyms
10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine
10H-Phenothiazine-10-propanamine, N,N-dimethyl-2-(trifluoromethyl)-
2-(Trifluoromethyl)promazine
2-Trifluoromethyl-10-(gamma-dimethylaminopropyl)phenothiazine
Adazine
EINECS 205-673-6
Fluopromazine
HSDB 3407
N,N-Dimethyl-2-(trifluoromethyl)-10H-phenothiazine-10-propanamine
Phenothiazine, 10-(3-(dimethylamino)propyl)-2-(trifluoromethyl)-
Psyquil
Siquil
Trifluopromazine
Triflupromazin
Triflupromazina
Triflupromazine
Triflupromazinum
Vesprin
Vetame
ATC A04AD06
N05AA05
CID 5568
CAS 000146543
Drugbank ID DB00508
TTD Drug ID DAP000294
SMILES CN(C)CCCN1C2=C(SC3=C1C=C(C=C3)C(F)(F)F)C=CC=C2
Formula C18H19F3N2S
Molweight 352.417
Atoms 24
LogP 5.3248
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 4
Transporter
AC-No.NameReferences
Q86UG4Solute carrier organic anion transporter family member 6A1 11111222
Q9Y345Sodium- and chloride-dependent glycine transporter 215374578
Cyamemazine

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Information Structure
Name Cyamemazine
Synonyms
10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine-2-carbonitrile
4-27-00-04111 (Beilstein Handbook Reference)
7204 R.E.
7204 RP
BRN 0093261
Ciamemazina
Cianatil
Cyamemazin
Cyamemazine
Cyamemazinum
Cyamepromazine
EINECS 222-594-2
F.I. 6229
Kyamepromazine
Tercian
TH 2602
ATC N05AA06
CID 62865
CAS 003546030
SMILES C[C@H](CN(C)C)CN1C2=C(SC3=C1C=C(C=C3)C#N)C=CC=C2
Formula C19H21N3S
Molweight 323.455
Atoms 23
LogP 4.42368
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
1A2Substrate 17951033
2C8Substrate 17951033
2C9Substrate 17951033
3A4Substrate 17951033
Transporter
AC-No.NameReferences
Q86UG4Solute carrier organic anion transporter family member 6A1 11111222
Q9Y345Sodium- and chloride-dependent glycine transporter 215374578
Chlorproethazine

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Information Structure
Name Chlorproethazine
Synonyms
2-Chloro-10-(3-diethylaminopropyl)phenothiazine
Chlorproethazine
Chlorproethazinum
Clorproetazina
EINECS 201-510-8
Neuriplege
RP 4909
ATC N05AA07
CID 65750
CAS 000084015
SMILES CCN(CC)CCCN1C2=CC=CC=C2SC3=C1C=C(Cl)C=C3
Formula C19H23ClN2S
Molweight 346.917
Atoms 23
LogP 5.7396
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 1
Transporter
AC-No.NameReferences
Q86UG4Solute carrier organic anion transporter family member 6A1 11111222
Q9Y345Sodium- and chloride-dependent glycine transporter 215374578