Compound - Results

Carbamazepine

Java required.


Information Structure
Name Carbamazepine
Synonyms
5-20-08-00247 (Beilstein Handbook Reference)
5-Carbamoyl-5H-dibenz(b,f)azepine
5-Carbamoyl-5H-dibenzo(b,f)azepine
5-Carbamyl-5H-dibenzo(b,f)azepine
5H-Dibenz(b,f)azepine-5-carboxamide
Amizepin
Biston
BRN 1246090
Carbamazepen
Carbamazepina
Carbamazepine
Carbamazepinum
Carbamezepine
Carbazepine
EINECS 206-062-7
Epitol
Finlepsin
G 32883
G-32883
Geigy 32883
HSDB 3019
Karbamazepin
Lexin
Neurotol
NSC 169864
Stazepine
Tegretal
Tegretol
Telesmin
Timonil
ATC N03AF01
CID 2554
CAS 000298464
Drugbank ID DB00564
TTD Drug ID DAP000129
SMILES NC(=O)N1C2=C(C=CC=C2)C=CC3=C1C=CC=C3
Formula C15H12N2O
Molweight 236.269
Atoms 18
LogP 4.1525
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
1A2Substrate Inhibitor Inducer umm
11760814
10096433
11760814
11760814
2A6Inducer 20719908
2B6Substrate Inducer 14977870
12386121
2C8Substrate Inducer 10907977
10096433
10096433
umm
2C9Inducer umm
11996015
2C19Inhibitor Inducer medicine.iupui.edu/flockhart
12458024
11996015
3A4Substrate Inducer 8748427
9860152
9536449
15708356
15298747
11103752
12386121
10466905
9630846
9536449
8877250
8817061
12642469
15519127
15298747
10096
9521735
umm
3A5Substrate Inducer 12673034
12673034
12464250
15673597
17374625
18420779
19370549
19744012
20702772
7917777
3A7Substrate 12642469
Phase2 interactions
NameReferences
UGT 17495417,
8968658
Transporter
AC-No.NameReferences
P08183P-glycoprotein 115371980
P78381UGT9606477
Q92887Canalicular multispecific organic anion transporter 120216337
Extrarenal fraction 1
Elimination half-life 15h
Oxcarbazepine

Java required.


Information Structure
Name Oxcarbazepine
Synonyms
10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
EINECS 249-188-8
GP 47680
Oxcarbazepina
Oxcarbazepine
Oxcarbazepinum
Trileptal
ATC N03AF02
CID 34312
CAS 028721075
Drugbank ID DB00776
TTD Drug ID DAP000528
SMILES NC(=O)N1C2=C(CC(=O)C3=C1C=CC=C3)C=CC=C2
Formula C15H12N2O2
Molweight 252.268
Atoms 19
LogP 3.4075
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2C19Inhibitor 12458024
15038401
12458024
12895138
3A4Inducer 12895138
17346248
15038401
3A5Inducer 12895138
Transporter
AC-No.NameReferences
P08183P-glycoprotein 115371980
P78381UGT9606477
Q92887Canalicular multispecific organic anion transporter 120216337
Extrarenal fraction 0.99
Elimination half-life 1.8h
Rufinamide

Java required.


Information Structure
Name rufinamide
Synonyms
1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-4-carboxamide
1-[(2,6-difluorophenyl)methyl]-1h-1,2,3-triazole-4-carboxamide
1-[(2,6-difluorophenyl)methyl]triazole-4-carboxamide
106308-44-5
1h-1,2,3-triazole-4-carboxamide, 1-((2,6-difluorophenyl)methyl)-
1h-1,2,3-triazole-4-carboxamide, 1-[(2,6-difluorophenyl)methyl]-
ac-1429
ac1l2v8c
akos005145897
banzel
banzel, Rufinamide
cgp 33101
cgp-33101
chembl1201754
cid129228
d05775
e-2080
hms3262o14
i06-1425
inovelon
mls001332513
mls001332514
molport-005-942-441
ncgc00165883-01
ncgc00165883-02
ncgc00165883-03
r8404_sigma
ruf-331
rufinamide
rufinamide (usan/inn)
s1256_selleck
sbb070637
smr000857122
syn-111
unii-wfw942pr79
xilep
zinc00007782
ATC N03AF03
CID 129228
CAS cid129228
Drugbank ID DB06201
TTD Drug ID DNC001042
Formula C15H12N2O2
Molweight 252.268
Atoms 19
LogP 3.4075
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
3A4Inducer fachinfo
Transporter
AC-No.NameReferences
P08183P-glycoprotein 115371980
P78381UGT9606477
Q92887Canalicular multispecific organic anion transporter 120216337
Extrarenal fraction 0.95
Elimination half-life 9h
Eslicarbazepine

Java required.


Information Structure
Name eslicarbazepine
Synonyms
104746-04-5
chembl315985
cid9881504
d09215
eslicarbazepine
eslicarbazepine (inn)
licarbazepine
s-(+)-10,11-dihydro-10-hydroxy-5h-dibenz[b,f]azepine-5-carboxamide
sbb062931
tx-010213
unii-s5vxa428r4
zinc00896938
ATC N03AF04
CID 9881504
CAS cid9881504
Formula C15H12N2O2
Molweight 252.268
Atoms 19
LogP 3.4075
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 3
Transporter
AC-No.NameReferences
P08183P-glycoprotein 115371980
P78381UGT9606477
Q92887Canalicular multispecific organic anion transporter 120216337
Extrarenal fraction 0.38
Elimination half-life 15.0h