Compound - Results

Ethotoin

Java required.


Information Structure
Name Ethotoin
Synonyms
1-Ethyl-2,5-dioxo-4-phenylimidazolidine
3-Ethyl-5-phenylhydantoin
3-Ethyl-5-phenylimidazolidin-2,4-dione
5-24-08-00005 (Beilstein Handbook Reference)
BRN 0188272
EINECS 201-665-1
Ethotoin
Ethotoine
Ethotoinum
Etotoina
HSDB 3580
Peganone
ATC N03AB01
CID 3292
CAS 000086351
Drugbank ID DB00754
TTD Drug ID DAP000512
SMILES CCN1C(=O)N[C@H](C1=O)C2=CC=CC=C2
Formula C11H12N2O2
Molweight 204.225
Atoms 15
LogP 1.5661
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2C19Inhibitor umm
2879902
Phenytoin

Java required.


Information Structure
Name Phenytoin
Synonyms
5,5-Diphenyl-2,4-imidazolidinedione
5,5-Diphenylhydantoin
5,5-Diphenylhydantoin (IUPAC)
5,5-Diphenylimidazolidin-2,4-dione
5,5-Dwufenylohydantoina
AI3-52498
Aleviatin
Auranile
Causoin
CCRIS 515
Comitoina
Convul
Danten
Dantinal
Dantoinal
Dantoinal Klinos
Dantoine
Denyl
Di-Hydan
Di-Lan
Di-Lan (VAN)
Di-Phetine
Didan TDC 250
Difenilhidantoina
Difenin
Difetoin
Difhydan
Dihycon
Dihydantoin
Dilabid
Dilantin
Dilantin Acid
Dilantin-125
Dilantine
Dillantin
Dintoin
Dintoina
Diphantoin
Diphedal
Diphedan
Diphenin
Diphenine
Diphentyn
Diphenylan
Diphenylhydantoin
Diphenylhydantoin (VAN)
Diphenylhydantoine
Diphenylhydatanoin
Ditoinate
DPH
DPH (VAN)
EINECS 200-328-6
Ekko
Ekko Capsules
Elepsindon
Enkelfel
Epamin
Epasmir 5
Epdantoin Simple
Epdantoine Simple
Epelin
Epifenyl
Epihydan
Epilan D
Epilan-D
Epilantin
Epinat
Epised
Eptal
Fenantoin Mn Pharma
Fenidantoin S
Fenitoina
Fentoin
Fenylepsin
Fenytoin Dak
Fenytoine
Gerot-epilan-D
Hidan
Hidantal
Hidantilo
Hidantina
Hidantina Senosian
Hidantina Vitoria
Hidantomin
Hydantal
Hydantoinal
Ictalis Simple
Idantoil
Idantoin
Iphenylhydantoin
Kessodanten
Labopal
Lehydan
Lepitoin
Lepsin
Minetoin
NCI-C55765
Neos-hidantoina
Neosidantoina
Novantoina
Novophenytoin
NSC 8722
OM Hidantoina Simple
OM-Hydantoine
Oxylan
Phanantin
Phanatine
Phenatine
Phenatoine
Phenhydanin
Phentoin
Phenytoin
Phenytoin AWD
Phenytoin-Gerot
Phenytoine
Phenytoinum
Ritmenal
Saceril
Sanepil
Silantin
Sinergina
Sodanthon
Sodantoin
Sodanton
Solantin
Sylantoic
Thilophenyl
TOIN
Toin Unicelles
Zentronal
Zentropil
ATC N03AB02
CID 1775
CAS 000057410
Drugbank ID DB00252
TTD Drug ID DAP000130
SMILES O=C1NC(=O)[C@](N1)(C2=CC=CC=C2)C3=CC=CC=C3
Formula C15H12N2O2
Molweight 252.268
Atoms 19
LogP 2.4272
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
2B6Inducer 9332469
14977870
15155833
15123723
2C8Substrate Inducer 11996015
umm
8851634
8819299
8095200
2009596
9393958
11996015
2C9Substrate Inhibitor Inducer 10208645
umm
14659971
12235444
11740344
11372587
10901705
10774639
10503815
10230773
9860067
12235444
2C18Substrate Inducer 11996015
10678302
12708941
2C19Substrate Inducer umm
15247556
12110367
10230773
11996015
medicine.iupui.edu/flockhart
3A4Substrate Inducer 10999732
umm
15247556
11103752
15155833
12110367
3A5Inducer 12673034
3A7Inducer 12673034
11B1Inhibitor 2519258
Phase2 interactions
NameReferences
GST 2890493
UGT 8968658
Transporter
AC-No.NameReferences
P33527Multidrug resistance-associated protein 120080116
P78381UDP-galactose translocator 9606477
Q86UG4SLCO6A1 10771259
Q92887Canalicular multidrug resistance protein12663688
Extrarenal fraction 1
Elimination half-life 22h
Amino(diphenylhydantoin) Valeric Acid

Java required.


Information Structure
Name Amino(diphenylhydantoin) valeric acid
Synonyms
Amino(diphenydantoin) Valeric Acid
Amino(diphenylhydantoin) Valeric Acid
EINECS 254-223-5
ATC N03AB03
CID 3084726
CAS 038964884
SMILES N[C@@H](CCCN1C(=O)N[C@](C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)C(O)=O
Transporter
AC-No.NameReferences
P33527Multidrug resistance-associated protein 120080116
P78381UDP-galactose translocator 9606477
Q86UG4SLCO6A1 10771259
Q92887Canalicular multidrug resistance protein12663688
Mephenytoin

Java required.


Information Structure
Name Mephenytoin
Synonyms
2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-
3-Ethylnirvanol
3-Methyl-5,5-phenylethylhydantoin
3-Methyl-5-ethyl-5-phenylhydantoin
5-24-08-00093 (Beilstein Handbook Reference)
5-Ethyl-3-methyl-5-phenyl-2,4(3H,5H)-imidazoledione
5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
5-Ethyl-3-methyl-5-phenylhydantoin
5-Ethyl-3-methyl-5-phenylimidazolidin-2,4-dione
5-Ethyl-5-fenyl-3-methylhydantoin
BRN 0017282
EINECS 200-012-8
Epiazin
Epilan
Fenantoin
HSDB 3581
Insulton
Mefenitoina
Mephenetoinum
Mephenytoin
Mephenytoine
Mephenytoinum
Mesantoin
Mesontoin
Methoin
Methyl Hydantoin
Methylphenetoin
Metydan
NSC-34652
Phenantoin
Phenylethylmethylhydantoin
Sacerno
Sedantoin
Sedantoinal
Triantoin
ATC N03AB04
CID 4060
CAS 000050124
Drugbank ID DB00532
TTD Drug ID DAP000508
SMILES CC[C@]1(NC(=O)N(C)C1=O)C2=CC=CC=C2
Formula C12H14N2O2
Molweight 218.252
Atoms 16
LogP 1.7402
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2C8Substrate 8110777
2C9Substrate 2299601
2669966
8013282
8361990
8824531
2C18Substrate 2299601
2669966
8013282
8361990
8824531
2C19Substrate Inhibitor 8822040
15753745
9131945
2D6Substrate 10424320
15499174
3A4Substrate 8423554
3A5Substrate 8423554
Transporter
AC-No.NameReferences
P33527Multidrug resistance-associated protein 120080116
P78381UDP-galactose translocator 9606477
Q86UG4SLCO6A1 10771259
Q92887Canalicular multidrug resistance protein12663688
Fosphenytoin

Java required.


Information Structure
Name Fosphenytoin
Synonyms
(3-Phosphoryloxymethyl)phenytoin
Cerebyx
Fosfenitoina
Fosphenytoin
Fosphenytoine
Fosphenytoinum
ATC N03AB05
CID 56339
CAS 093390819
Drugbank ID DB01320
TTD Drug ID DAP000520
SMILES OP(O)(=O)OCN1C(=O)N[C@](C1=O)(C2=CC=CC=C2)C3=CC=CC=C3
Formula C16H15N2O6P
Molweight 362.274
Atoms 25
LogP 1.8155
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 7
CYP interactions
NameRelationsReferences
2B6Inhibitor umm
2C8Substrate Inhibitor umm
2C9Substrate Inhibitor umm
2C19Substrate Inhibitor umm
3A4Substrate Inhibitor umm
Transporter
AC-No.NameReferences
P33527Multidrug resistance-associated protein 120080116
P78381UDP-galactose translocator 9606477
Q86UG4SLCO6A1 10771259
Q92887Canalicular multidrug resistance protein12663688