Compound - Results

Phenazone

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Information Structure
Name Phenazone
Synonyms
1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
1-Phenyl-2,3-dimethyl-5-pyrazolone
1-Phenyl-2,3-dimethylpyrazole-5-one
2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one
2,3-Dimethyl-1-phenyl-5-pyrazolone
3-Antipyrine
AI3-15293
Analgesine
Anodynin
Anodynine
Antipirin
Antipyrin
Antipyrine
Antipyrinum
Apirelina
Azophen
Azophene
Azophenum
CCRIS 1369
Dimethyloxychinizin
Dimethyloxyquinazine
EINECS 200-486-6
Fenazon
Fenazona
Fenazone
Methozin
NSC 7945
Oxydimethylquinazine
Parodyne
Phenazon
Phenazone
Phenazone (pharmaceutical)
Phenazonum
Phenozone
Phenylon
Phenylone
Pyrazophyl
Sedatin
Sedatine
ATC N02BB01
S02DA03
CID 2206
CAS 000060800
Drugbank ID DB01435
TTD Drug ID DNC001118
SMILES CN1N(C(=O)C=C1C)C2=CC=CC=C2
Formula C11H12N2O
Molweight 188.226
Atoms 14
LogP 1.4844
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Substrate 8681486
8801065
11847531
11996015
2A6Substrate 8801065
2B6Substrate Inhibitor 9172960
8681486
2C8Substrate 8681486
2C9Substrate 8681486
8801065
2C18Substrate 8681486
2C19Substrate Inhibitor 9172960
8801065
2D6Substrate Inhibitor 9172960
8801065
2E1Substrate 8801065
3A4Substrate Inhibitor 9172960
8681486
Phase2 interactions
NameReferences
NAT 10678296,
7665722
Extrarenal fraction 0.95
Elimination half-life 12h
Metamizole Sodium

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Information Structure
Name Metamizole sodium
Synonyms
(Antipyrinylmethylamino)methanesulfonic Acid Sodium Salt
1-Phenyl-2,3-dimethyl-4-methylamino-5-pyrazolon-N-methanesulfonsaeuren Natrium
1-Phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate Sodium
1-Phenyl-2,3-dimethylpyrazolone-(5)-4-methylaminomethanesulfonic Acid Sodium
4-Methylamino-1,5-dimethyl-2-phenyl-3-pyrazolone Sodium Methanesulfonate
4-Sodium Methanesulfonate Methylamine-antipyrine
Alginodia
Algocalmin
Algopyrine
Aminopyrine Sodium Sulfonate
Analgin
Analgine
Analginum
Antipyrine, 4-(methylamino)-, Monomethosulfate, Sodium Salt
ARPF
Barone
Bonpyrin
CCRIS 4443
Conmel
Di-podil
Dimethone
Diprofarn
Dipyrone
Dipyrone Anhydrous
EINECS 200-694-7
Farmolisina
Fenildimetil-pirazolon-metilaminometansolfonato Sodico
Feverall
Fevonil
Gifaril
Keypyrone
Meamizol Sodico
Metamizol
Metamizol Sodico
Metamizole
Metamizole Sodique
Metamizole Sodium
Metamizolnatrium
Metamizolo
Metamizolo Sodico
Metamizolum
Metamizolum Natricum
Metapyrin
Methampyrone
Methanesulfonic Acid, (antipyrinylmethylamino)-, Sodium Salt
Methylaminoantipyrine Sodium Methanesulfonate
Methylaminophenyldimethylpyrazolone Methanesulfonate Sodium
Methylmelubrin
Metilon
Narone
Natrium Novaminsulfonicum
Neo-melubrine
Neomelurbrin
Nevralgina
Noramidopyrine Methanesulfonate Sodium
Noramidopyrine Methanesulfonate Sodium Salt
Noramidopyrinium-methanesulphate Natrium
Noraminophenazone
Noraminophenazone Methanesulfonate Sodium Salt
Noraminophenazone Sodium Mesylate
Noraminopyrine Methanesulfonate Sodium
Novalgetol
Novalgin
Novamidazophen
Novamidazophenum
Novaminophenazone
Novaminsulfon
Novaminsulfone
Novaminsulfone Sodium
Novaminsulfonium
Novaminsulfonum
Noveltex
Optalgin
Paralgin
Pharmalgine
Phenyl Dimethyl Pyrazolon Methyl Aminomethane Sodium Sulfonate
Pyralgin
Pyretin
Pyretin (pharmaceutical)
Pyrojec
Sodium (antipyrinylmethylamino)methanesulfonate
Sodium 1-phenyl-2,3-dimethyl-4-methylaminopyrazolon-N-methanesulfonate
Sodium 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylamino Methanesulfonate
Sodium 4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolone 4-methanesulfonate
Sodium Methylaminoantipyrine Methanesulfonate
Sodium Noramidopyrine Methanesulfonate
Sodium Novaminsulfonate
Sodium Phenyldimethylpyrazolon-methylamino-methane Sulfonate
Sulpin
Sulpyrin
Sulpyrine
Sulpyrinum
ATC N02BB02
CID 522325
CAS 000068893
Herbal origin fruit of Fiveleaf Akebia
SMILES CN(CS([O-])(=O)=O)C1=C(C)N(C)N(C1=O)C2=CC=CC=C2
Formula C13H16N3NaO4S
Molweight 333.339
Atoms 22
LogP 1.5041
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
2B6Inducer 17344806
3A4Inducer 17344806
Phase2 interactions
NameReferences
GST 2070486
NAT 20884738,
20884738
Extrarenal fraction 0.8
Elimination half-life 2.5h
Aminophenazone

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Information Structure
Name Aminophenazone
Synonyms
1,5-Dimethyl-4-dimethylamino-2-phenyl-3-pyrazolone
1-Phenyl-2,3-dimethyl-4-dimethylaminopyrazol-5-one
2,3-Dimethyl-4-dimethylamino-1-phenyl-5-pyrazolone
3-Keto-1,5-dimethyl-4-dimethylamino-2-phenyl-2,3-dihydropyrazole
3-Pyrazolin-5-one, 4-(dimethylamino)-2,3-dimethyl-1-phenyl-
3H-Pyrazol-3-one, 4-(dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-
4-(Dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
4-(Dimethylamino)antipyrine
4-Dimethylamino-1-phenyl-2,3-dimethylpyrazolone
4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
4-Dimethylamino-2,3-dimethyl-1-phenyl-5-pyrazolone
4-Dimethylaminophenazone
Amidazofen
Amidazophen
Amidazophene
Amidazophenum
Amidofebrin
Amidofen
Amidophen
Amidophenazone
Amidopyrazoline
Amidopyrin
Amidopyrine
Amidopyrinum
Aminofenazona
Aminofenazone
Aminophenazon
Aminophenazone
Aminophenazonum
Aminopyrene
Aminopyrin
Aminopyrine
Aminopyrinum
Anafebrina
Antipyrine, 4-(dimethylamino)-
Brufaneuxol
CCRIS 2907
Dereuma
Dimapyrin
Dimethylamino-analgesine
Dimethylaminoantipyrine
Dimethylaminoazophene
Dimethylaminophenazon
Dimethylaminophenazone
Dimethylaminophenyldimethylpyrazolin
Dimethylaminophenyldimethylpyrazolone
Dipirin
Dipyrin
Dipyrine
EINECS 200-365-8
Eufibron
Febrinina
Febron
HSDB 2135
Hyparon
Itamidone
Mamallet-A
Netsusarin
Novamidon
NSC 4993
Piramidon
Pirazon
Piridol
Piromidina
Polinalin
Pyradone
Pyramidon
Pyramidone
ATC N02BB03
CID 6009
CAS 000058151
Herbal origin Ba Xia Ga
SMILES CN(C)C1=C(C)N(C)N(C2=CC=CC=C2)C1=O
Formula C13H17N3O
Molweight 231.294
Atoms 17
LogP 1.5504
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Substrate 10199594
11996015
2C8Substrate 10199594
2C9Inhibitor 11853173
2C18Substrate 10199594
10199594
2C19Substrate Inhibitor 11853173
10199594
10784435
2D6Substrate 10199594
7645307
3A4Substrate 10199594
3A7Substrate 9493761
11996015
17ASubstrate 10199594
Propyphenazone

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Information Structure
Name Propyphenazone
Synonyms
1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-one
1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-one
2,3-Dimethyl-4-isopropyl-1-phenyl-3H-pyrazolin-5-one
3-Pyrazolin-5-one, 2,3-dimethyl-4-isopropyl-1-phenyl-
3-Pyrazolin-5-one, 4-isopropyl-2,3-dimethyl-1-phenyl-
4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
4-Isopropylantipyrine
5-24-01-00408 (Beilstein Handbook Reference)
5-Pyrazolone, 1-phenyl-2,3-dimethyl-4-isopropyl-
BRN 0204533
CCRIS 6716
EINECS 207-539-2
Isopropylantipyrin
Isopropylantipyrine
Isopropylantipyrinum
Isopropylphenazone
Isopropyrine
Larodon
Propifenazona
Propifenazone
Propyphenazone
Propyphenazonum
ATC N02BB04
CID 3778
CAS 000479925
SMILES CC(C)C1=C(C)N(C)N(C2=CC=CC=C2)C1=O
Formula C14H18N2O
Molweight 230.306
Atoms 17
LogP 2.6078
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 1
Extrarenal fraction 0.9
Elimination half-life 12h
Nifenazone

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Information Structure
Name Nifenazone
Synonyms
2,3-dimethyl-4-nicotinamido-1-phenyl-3-pyrazolin-5-on
4-(Nicotinamido)antipyrine
4-(Nicotinoylamino)antipyrine
4-Nicotinoylamido-1-phenyl-2,3-dimethyl-5-pyrazolone
5-25-14-00153 (Beilstein Handbook Reference)
Anicotinoylantipyrine
BRN 0307504
EINECS 218-387-1
N-(2,3-Dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)nicotinamid
N-Antipyrinylnicotinamide
Niapyrin
Nicazane
Nicodon
Nicodone
Nicofesone
Nicophesone
Nicophezon
Nicopyron
Nicoreumal
Nicoron
Nicotazone
Nicotinamide, N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-
Nicotinic Acid 4-antipyrilamide
Nicotinic Acid, Amidophenyldimethylpyrazolone
Nicotinoylaminoantipyrine
Nicotinsaeureamidophenyldimethylpyrazolons
Nicozone
Nifenazon
Nifenazona
Nifenazone
Nifenazonum
Nikodon
Nikofezon
Phenicazone
Thylin
ATC M02AA24
N02BB05
CID 4487
CAS 002139471
SMILES CN1N(C2=CC=CC=C2)C(=O)C(NC(=O)C3=CN=CC=C3)=C1C
Formula C17H16N4O2
Molweight 308.335
Atoms 23
LogP 2.2047
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 4