Compound - Results

Probenecid

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Information Structure
Name Probenecid
Synonyms
4-((Dipropylamino)sulfonyl)benzoic Acid
4-(Di-n-propylsulfamoyl)benzoesaeure
4-(Dipropylsulfamoyl)benzoic Acid
4-(N,N-Dipropylsulfamoyl)benzoesaeure
4-11-00-00691 (Beilstein Handbook Reference)
AI3-50078
Apurina
Benecid
Benemid
Benemide
Benuryl
Benzoic Acid, P-(dipropylsulfamoyl)-
BRN 2815775
CCRIS 3643
Col-Probenecid
DRG-0053
EINECS 200-344-3
Ethamide
HSDB 3387
NCI-C56097
NSC 18786
p-(Dipropylsulfamoyl)benzoic Acid
Polycillin-BRB
Probalan
Probampacin
Probecid
Proben
Probenecid
Probenecid Acid
Probenecida
Probenecide
Probenecidum
Probenemid
Probenid
Probexin
Prolongine
Robenecid
Synergid R
Tubophan
Uricosid
ATC M04AB01
CID 4911
CAS 000057669
Drugbank ID DB01032
TTD Drug ID DAP001292
SMILES CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O
Formula C13H19NO4S
Molweight 285.359
Atoms 19
LogP 3.2763
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 5
CYP interactions
NameRelationsReferences
2C8Inducer 15915352
2C9Inhibitor 710028
2C19Inhibitor 710028
3A4Inducer 15915352
Phase2 interactions
NameReferences
UGT 11823755,
1930271
Transporter
AC-No.NameReferences
O15440Multidrug resistance-associated protein 516337112
O43511Pendrin 12388138
P08183Multidrug resistance protein 111118294
P33527ATP-binding cassette sub-family C member 119454316
P46721OATP-A11408557
Q4U2R8Renal organic anion transporter 111861798
Q8TCC7Organic anion transporter 317314201
Q92887Multidrug resistance-associated protein 219508886
Q9Y694Novel liver transporter12023506
Extrarenal fraction 0.9
Elimination half-life 5h
Sulfinpyrazon

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Information Structure
Name Sulfinpyrazon
Synonyms
1,2-Diphenyl-3,5-dioxo-4-(2-phenyl-sulfinyl-aethyl)-pyrazolidin
1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)pyrazolidine
1,2-Diphenyl-4-(2-(phenylsulfinyl)ethyl)-3,5-pyrazolidinedione
1,2-Diphenyl-4-(2-phenylsulfinethyl)-3,5-pyrazolidinedione
4-(2-Benzenesulfinylethyl)-1,2-diphenylpyrazolidine-3,5-dione
4-(Phenylsulfoxyethyl)-1,2-diphenyl-3,5-pyrazolidinedione
5-25-02-00397 (Beilstein Handbook Reference)
Anturane
Anturanil
Anturano
Anturidin
BRN 0713597
Diphenylpyrazone
EINECS 200-357-4
Enturen
G 28,315
G 28315
HSDB 3396
NSC 75925
Sulfinpirazona
Sulfinpyrazon
Sulfinpyrazone
Sulfinpyrazonum
Sulfoxyphenylpyrazolidine
Sulphinpyrazone
USAF GE-13
ATC B01AC12
M04AB02
CID 5342
CAS 000057965
Drugbank ID DB01138
TTD Drug ID DAP000794
SMILES O=C1[C@H](CCS(=O)C2=CC=CC=C2)C(=O)N(N1C3=CC=CC=C3)C4=CC=CC=C4
Formula C23H20N2O3S
Molweight 404.482
Atoms 29
LogP 4.7912
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2B6Inducer 14977870
2C8Substrate umm
11996015
2C9Substrate Inhibitor 15197517
umm
15197517
3A4Substrate Inhibitor Inducer umm
11996015
12065438
11302937
10219967
Transporter
AC-No.NameReferences
P33527LTC4 transporter9885294
Q5T3U5ATP-binding cassette sub-family C member 1018445659
Q92887Canalicular multispecific organic anion transporter 114569069
Extrarenal fraction 0.55
Elimination half-life 4h
Benzbromarone

Java required.


Information Structure
Name Benzbromarone
Synonyms
3,5-Dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl Ketone
5-18-02-00335 (Beilstein Handbook Reference)
Benzbromarone
Benzbromaronum
Benzobromarona
Benzofuran, 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-
BRN 0273668
Desuric
EINECS 222-630-7
Exurate
Hipurik
L 2214
L 2214-Labaz
L-2214
L2214
L2214-Labaz
Minuric
MJ 10061
Normurat
NSC 85433
Uricovac
Urinorm
ATC M04AB03
CID 2333
CAS 003562843
TTD Drug ID DCL000306
SMILES CCC1=C(C(=O)C2=CC(Br)=C(O)C(Br)=C2)C3=CC=CC=C3O1
Formula C17H12Br2O3
Molweight 424.083
Atoms 22
LogP 5.4568
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2C9Inhibitor 15955872
15170332
12814975
15955872
10613612
Transporter
AC-No.NameReferences
B5ME56SLC22A12 16135657
Q92887Canalicular multispecific organic anion transporter 118845662
Extrarenal fraction 1
Elimination half-life 3h
Isobromindione

Java required.


Information Structure
Name Isobromindione
Synonyms
1H-Indene-1,3(2H)-dione, 5-bromo-2-phenyl-
2-Fenil-5-bromo-indandione
4-07-00-02572 (Beilstein Handbook Reference)
5-Bromo-2-phenylindan-1,3-dione
BRN 1878513
EINECS 216-000-0
Isobromindiona
Isobromindione
Isobromindionum
Uridion
ATC M04AB04
CID 68953
CAS 001470355
SMILES BrC1=CC2=C(C=C1)C(=O)[C@@H](C3=CC=CC=C3)C2=O
Formula C15H9BrO2
Molweight 301.135
Atoms 18
LogP 3.6119
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 2
Transporter
AC-No.NameReferences
B5ME56SLC22A12 16135657
Q92887Canalicular multispecific organic anion transporter 118845662