Compound - Results

Nabumetone

Java required.


Information Structure
Name Nabumetone
Synonyms
4-(6-Methoxy-2-naphthalenyl)-2-butanone
4-(6-Methoxy-2-naphthyl)-2-butanone
Arthaxan
Balmox
BRL 14777
BRN 2103472
Consolan
Dolsinal
Flambate
Listran
Mebutan
Nabumetona
Nabumetone
Nabumetonum
Prodac
Relafen
Relif
Relifen
Relifex
Unimetone
ATC M01AX01
CID 4409
CAS 042924538
Drugbank ID DB00461
TTD Drug ID DAP000735
SMILES COC1=CC2=C(C=C1)C=C(CCC(C)=O)C=C2
Formula C15H16O2
Molweight 228.286
Atoms 17
LogP 3.37
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
1A2Substrate 19204080
Phase2 interactions
NameReferences
GST 9545594
Extrarenal fraction 0.6
Elimination half-life 24.0h
Niflumic Acid

Java required.


Information Structure
Name Niflumic acid
Synonyms
2-(3-(Trifluoromethyl)-phenyl)aminonicotinic Acid
2-(3-(Trifluoromethyl)anilino)nicotinic Acid
5-22-13-00598 (Beilstein Handbook Reference)
Acide Niflumique
Acido Niflumico
Acidum Niflumicum
Actol
Aza-2 Dimethyl-2,3 (tetrazolyl-5)-6 Diphenylamino
BRN 0489360
CCRIS 5740
EINECS 224-516-2
Forenol
Landruma
Niflumic Acid
Nifluril
SC 1332
UP 83
ATC M01AX02
M02AA17
CID 4488
CAS 004394007
Drugbank ID DB04552
TTD Drug ID DAP000972
SMILES OC(=O)C1=C(NC2=CC(=CC=C2)C(F)(F)F)N=CC=C1
Formula C13H9F3N2O2
Molweight 282.218
Atoms 20
LogP 3.6152
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 7
Phase2 interactions
NameReferences
UGT 16783480,
16278927,
15571295
Transporter
AC-No.NameReferences
P53985Monocarboxylate transporter 18557697
P78381SLC35A216783480
Extrarenal fraction 0.85
Elimination half-life 2.0h
Azapropazone

Java required.


Information Structure
Name Azapropazone
Synonyms
1,2-Dihydro-3-dimethylamino-7-methyl-1,2-(propylmalonyl)-1,2,4-benzotriazine
3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine
5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione
AHR 3018
AHR-3018
Apazone
Azapropazon
Azapropazona
Azapropazone
Azapropazone (anhydrous)
Azapropazonum
BRN 0623763
Cinnamin
Cinnopropazone
EINECS 236-913-8
MI 85
Mitrolan
NSC-102824
Prolix
Prolixan
Prolixan 300
Rheumox
Sinnamin
Xani
ATC M01AX04
CID 26098
CAS 013539598
SMILES CCC[C@H]1C(=O)N2N(C1=O)C(=NC3=C2C=C(C)C=C3)N(C)C
Formula C16H20N4O2
Molweight 300.356
Atoms 22
LogP 2.4847
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
2C9Inhibitor 8806399
Transporter
AC-No.NameReferences
P53985Monocarboxylate transporter 18557697
P78381SLC35A216783480
Extrarenal fraction 0.4
Elimination half-life 12.0h
Glucosamine

Java required.


Information Structure
Name Glucosamine
Synonyms
2-Amino-2-deoxy-beta-D-glucopyranose
2-Amino-2-deoxy-D-glucose
2-Amino-2-deoxyglucose
4-04-00-02017 (Beilstein Handbook Reference)
BRN 1724602
Chitosamine
D-Glucosamine
D-Glucose, 2-amino-2-deoxy-
EINECS 222-311-2
Glucosamina
Glucosamine
Glucosaminum
ATC M01AX05
CID 439213
CAS 003416248
Drugbank ID DB01296
TTD Drug ID DAP001097
SMILES N[C@@H]1[C@@H](O)O[C@@H](CO)[C@H](O)[C@H]1O
Formula C6H13NO5
Molweight 179.171
Atoms 17
LogP -2.5547
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
2C19Substrate 11531003
2E1Substrate 11531003
Transporter
AC-No.NameReferences
P53985Monocarboxylate transporter 18557697
P78381SLC35A216783480
Benzydamine

Java required.


Information Structure
Name Benzydamine
Synonyms
1-Benzyl-3-(3-(dimethylamino)propoxy)-1H-indazole
5-23-11-00248 (Beilstein Handbook Reference)
Bencidamina
Benzidamina
Benzidamine
Benzindamine
Benzydamine
Benzydaminum
BRN 0896536
C 1523
EINECS 211-388-8
ATC A01AD02
G02CC03
M01AX07
M02AA05
CID 12555
CAS 000642728
SMILES CN(C)CCCOC1=NN(CC2=CC=CC=C2)C3=C1C=CC=C3
Formula C19H23N3O
Molweight 309.405
Atoms 23
LogP 3.4151
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
1A1Substrate 11012553
1A2Substrate umm
11012553
11996015
2C19Substrate 11012553
11531003
2D6Substrate umm
11012553
2E1Substrate 11531003
3A4Substrate umm
11012553
Transporter
AC-No.NameReferences
P53985Monocarboxylate transporter 18557697
P78381SLC35A216783480
Proquazone

Java required.


Information Structure
Name Proquazone
Synonyms
1-Isopropyl-7-methyl-4-phenyl-2(1H)-quinazolinone
5-24-04-00375 (Beilstein Handbook Reference)
Arthrex
Biarison
BRN 0889725
EINECS 245-203-7
Isopropyl-7-methyl-4-phenyl-2(1H)-quinazolinone
Proquazona
Proquazone
Proquazonum
RU 43715
SaH 43-715
Sandoz 43-715
ATC M01AX13
CID 31508
CAS 022760185
SMILES CC(C)N1C(=O)N=C(C2=CC=CC=C2)C3=C1C=C(C)C=C3
Formula C18H18N2O
Molweight 278.348
Atoms 21
LogP 3.9528
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 2
Transporter
AC-No.NameReferences
P53985Monocarboxylate transporter 18557697
P78381SLC35A216783480
Nimesulide

Java required.


Information Structure
Name Nimesulide
Synonyms
4-Nitro-2-phenoxy-methanesulfonanilide
4-Nitro-2-phenoxymethansulfonanilid
Aulin
BRN 2421175
EINECS 257-431-4
Flogovital
Mesulid
N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide
Nimed
Nimesulida
Nimesulide
Nimesulidum
R 805
R-805
Sulidene
ATC M01AX17
M02AA26
CID 4495
CAS 051803782
TTD Drug ID DPR000079
SMILES CS(=O)(=O)NC1=C(OC2=CC=CC=C2)C=C(C=C1)[N+]([O-])=O
Formula C13H12N2O5S
Molweight 308.31
Atoms 21
LogP 4.4356
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
2C9Substrate Inhibitor
Transporter
AC-No.NameReferences
P53985Monocarboxylate transporter 18557697
P78381SLC35A216783480
Extrarenal fraction 1.0
Elimination half-life 3.5h
Feprazone

Java required.


Information Structure
Name Feprazone
Synonyms
1,2-Diphenyl-4-(3-methyl-2-butenyl)-3,5-pyrazolidinedione
3,5-Pyrazolidinedione, 4-(3-methyl-2-butenyl)-1,2-diphenyl-
4-(2-Isopentenyl)-1,2-diphenyl-3,5-pyrazolidinedione
4-(3-Methyl-2-butenyl)-1,2-diphenyl-3,5-pyrazolidinedione
4-(beta-Isoamylenyl)-1,2-diphenyl-3,5-pyrazolidinedione
4-Prenyl-1,2-diphenyl-3,5-dioxopyrazolidine
4-Prenyl-1,2-diphenyl-3,5-pyrazolidinedione
Analud
BRN 3984862
DA 2370
EINECS 250-324-3
Fenilprenazone
Feprazona
Feprazone
Feprazonum
Methrazone
Phenylprenazone
Pheprazone
Prenazone
Zepelin
ATC M01AX18
M02AA16
CID 35455
CAS 030748299
SMILES CC(C)=C/C[C@H]1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3
Formula C20H20N2O2
Molweight 320.385
Atoms 24
LogP 4.0839
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 2
Transporter
AC-No.NameReferences
P53985Monocarboxylate transporter 18557697
P78381SLC35A216783480
Diacerein

Java required.


Information Structure
Name Diacerein
Synonyms
1,8-Diacetoxyanthraquinone-3-carboxylic Acid
3-10-00-04790 (Beilstein Handbook Reference)
4,5-Diacetylrhein
9,10-Dihydro-4,5-diacetoxy-9,10-2-anthracenecarboxylic Acid
9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroic Acid Diacetate
Artrodar
BRN 2184909
Diacerein
Diacereina
Diacereine
Diacereinum
Diacerhein
Diacetylrhein
EINECS 237-310-2
Rhein, Diacetate (6CI)
SF-277
ATC M01AX21
CID 26248
CAS 013739021
TTD Drug ID DNC000544
SMILES CC(=O)OC1=C2C(=O)C3=C(C=C(C=C3OC(C)=O)C(O)=O)C(=O)C2=CC=C1
Formula C19H12O8
Molweight 368.294
Atoms 27
LogP 2.0108
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 8
Transporter
AC-No.NameReferences
P53985Monocarboxylate transporter 18557697
P78381SLC35A216783480
Morniflumate

Java required.


Information Structure
Name Morniflumate
Synonyms
2-Morpholinoethyl 2-(3-trifluoromethylanilino)nicotinat
2-Morpholinoethyl 2-(alpha,alpha,alpha-trifluoro-m-toluidino)nicotinate
Morniflumate
Morniflumato
Morniflumatum
Niflumic Acid Beta-morpholinoethyl Ester
Nifluminsaeure 2-morpholinoethylester
UP 164
ATC M01AX22
CID 72106
CAS 065847850
SMILES FC(F)(F)C1=CC(NC2=NC=CC=C2C(=O)OCCN3CCOCC3)=CC=C1
Formula C19H20F3N3O3
Molweight 395.376
Atoms 28
LogP 3.3439
Rotatable Bonds 8
H-Bond Donors 0
H-Bond Acceptors 9
Transporter
AC-No.NameReferences
P53985Monocarboxylate transporter 18557697
P78381SLC35A216783480
Tenidap

Java required.


Information Structure
Name Tenidap
Synonyms
(Z)-5-Chloro-3-(alpha-hydroxy-2-thenylidene)-2-oxo-1-indolinecarboxamide
CP 66,248
Tenidap
Tenidapum
ATC M01AX23
CID 60712
CAS 120210482
SMILES NC(=O)N1C(=O)C(=C(/O)C2=CC=CS2)C3=C1C=CC(Cl)=C3
Formula C14H9ClN2O3S
Molweight 320.751
Atoms 21
LogP 3.9199
Rotatable Bonds 3
H-Bond Donors 2
H-Bond Acceptors 6
Transporter
AC-No.NameReferences
C9J6Y3SLC26A6 21976599
Q9Y6R1Electrogenic sodium bicarbonate cotransporter 119710533
Oxaceprol

Java required.


Information Structure
Name Oxaceprol
Synonyms
AHP 200
EINECS 251-780-6
Jonctum
Oxaceprol
Oxaceprolum
Tejuntivo
ATC D11AX09
M01AX24
CID 65784
CAS 033996337
SMILES CC(=O)N1C[C@H](O)C[C@H]1C(O)=O
Formula C7H11NO4
Molweight 173.167
Atoms 12
LogP -1.0094
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 4
Transporter
AC-No.NameReferences
C9J6Y3SLC26A6 21976599
Q9Y6R1Electrogenic sodium bicarbonate cotransporter 119710533
Chondroitin Sulfate

Java required.


Information Structure
Name Chondroitin sulfate
Synonyms
Chondroitin Polysulfate
Chondroitin Sulfate
Chondroitin Sulfates
Chondroitin Sulfuric Acid
Chondroitin Sulphate
Chonsurid
EINECS 232-696-9
ATC M01AX25
CID 24766
CAS 009007287
SMILES CC(=O)N[C@H]1[C@H](O)O[C@H](OS(O)(=O)=O)[C@H](O)[C@@H]1O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O
Formula C13H21NO15S
Molweight 463.369
Atoms 40
LogP -3.9048
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 16
Transporter
AC-No.NameReferences
C9J6Y3SLC26A6 21976599
Q9Y6R1Electrogenic sodium bicarbonate cotransporter 119710533