Compound - Results

Flutamide

Java required.


Information Structure
Name Flutamide
Synonyms
4-Nitro-3-trifluoromethylisobutyranilide
alpha,alpha,alpha-Trifluoro-2-methyl-4-nitro-m-propionotoluidide
BRN 2157663
CCRIS 7246
Cebatrol, Veterinary
EINECS 236-341-9
Eulexin
Flutamida
Flutamide
Flutamidum
Hams F-12 Medium
NFBA
Niftholide
Niftolide
NSC 215876
Sch 13521
ATC L02BB01
CID 3397
CAS 013311847
Drugbank ID DB00499
TTD Drug ID DAP000301
SMILES CC(C)C(=O)NC1=CC(=C(C=C1)[N+]([O-])=O)C(F)(F)F
Formula C11H11F3N2O3
Molweight 276.212
Atoms 19
LogP 3.8043
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 7
CYP interactions
NameRelationsReferences
1A1Substrate 11160641
1A2Substrate Inhibitor 17403914
umm
9351907
8386241
9351907
1B1Substrate Inhibitor 11160641
11160641
2C19Substrate 17403914
3A4Substrate 17403914
9351907
3A5Substrate 17403914
Extrarenal fraction 1
Elimination half-life 7.8h
Nilutamide

Java required.


Information Structure
Name Nilutamide
Synonyms
1-(3-Trifluoromethyl-4-nitrophenyl)-4,4-dimethylimidazolidine-2,5-dione
5,5-Dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-2,4-imidazolidinedione
5,5-Dimethyl-3-(alpha,alpha,alpha-trifluoro-4-nitro-m-tolyl)hydantoin
5-24-05-00358 (Beilstein Handbook Reference)
Anandron
BRN 0841906
Nilandron
Nilandrone
Nilutamida
Nilutamide
Nilutamidum
RU 23908-10
RU-23908
ATC L02BB02
CID 4493
CAS 063612500
Drugbank ID DB00665
TTD Drug ID DAP000302
SMILES CC1(C)NC(=O)N(C2=CC(=C(C=C2)[N+]([O-])=O)C(F)(F)F)C1=O
Formula C12H10F3N3O4
Molweight 317.221
Atoms 22
LogP 3.3654
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 8
CYP interactions
NameRelationsReferences
2C8Inhibitor 1785203
2C9Inhibitor 1785203
2C19Substrate Inhibitor 1785203
medicine.iupui.edu/flockhart
1785203
Bicalutamide

Java required.


Information Structure
Name Bicalutamide
Synonyms
(+-)-4-Cyano-alpha,alpha,alpha-trifluoro-3-((p-fluorophenyl)sulfonyl)-2-methyl-m-lactotoluidide
Bicalutamide
BRN 5364666
Casodex
ICI 176334
ATC L02BB03
CID 2375
CAS 090357065
Drugbank ID DB01128
SMILES C[C@](O)(CS(=O)(=O)C1=CC=C(F)C=C1)C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F
Formula C18H14F4N2O4S
Molweight 430.373
Atoms 29
LogP 4.03338
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 10
CYP interactions
NameRelationsReferences
2C9Inhibitor 15509184
2C19Inhibitor 15509184
2D6Inhibitor 15509184
3A4Substrate Inhibitor 15509184