Compound - Results

Cisplatin

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Information Structure
Name Cisplatin
Synonyms
Abiplatin
AI3-62048
Biocisplatinum
Briplatin
CACP
CCRIS 221
CDDP
cis Diamminedichloroplatinum
cis-DDP
cis-Diaminedichloroplatinum
cis-Diaminodichloroplatinum(II)
cis-Diamminedichloroplatinum
cis-Diamminedichloroplatinum(II)
cis-Diammineplatinum(II) Dichloride
cis-Dichlorodiamine Platinum(II)
cis-Dichlorodiaminoplatinum
cis-Dichlorodiaminoplatinum(II)
cis-Dichlorodiammine Platinum(II)
cis-Dichlorodiammineplatinum
cis-Dichlorodiammineplatinum(II)
cis-Dichlorodiamminoplatinum(II)
cis-Platin
cis-Platinous Diaminodichloride
cis-Platinous Diammine Dichloride
cis-Platinum
cis-Platinum Diamminedichloride
cis-Platinum(II)
cis-Platinum(II) Diamine Dichloride
cis-Platinum(II) Diaminedichloride
cis-Platinum(II) Diaminodichloride
cis-Platinum(II) Diamminedichloride
Cisplatin
Cisplatine
Cisplatino
Cisplatinum
Cisplatyl
cisPt(II)
CPDD
DDP (antitumor Agent)
DDPt
EINECS 239-733-8
HSDB 3939
NCI-C55776
Neoplatin
NK 801
NSC-119875
PDD
Peyrones Chloride
Platiblastin
Platidiam
Platidiam Lachema BRNO
Platinol
Platinum Diamminodichloride
Platinum(II), Diamminedichloro-, Cis-
Platinum, Diamminedichloro-, Cis-
Platosin
SPI 77
TR 170
ATC L01XA01
CID 5311048
CAS 015663271
SMILES N[Pt](N)(Cl)Cl
Formula CH4Cl2N2
Molweight 114.962
Atoms 5
LogP 1.3933
Rotatable Bonds 0
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
2B6Inhibitor 19378397
2E1Substrate Inducer 12675844
16251482
Phase2 interactions
NameReferences
GST 8296325,
18852128,
7954341,
1394205,
14614026
UGT 17303299
Transporter
AC-No.NameReferences
O15244Solute carrier family 22 member 216242669
O15245Solute carrier family 22 member 120858838
O15431High affinity copper uptake protein 115634647
O15432Probable low affinity copper uptake protein 2 20930109
P08183Multidrug resistance protein 110433011
P19634SLC9A1 20841472
P33527Multidrug resistance-associated protein 111687904
P35670Wilson disease-associated protein17978167
P46059Intestinal H(+)/peptide cotransporter16253763
P55011Solute carrier family 12 member 218769031
Q86UG4Organic anion-transporting polypeptide 6A1 8068032
Q92887ATP-binding cassette sub-family C member 29571149
Q99624Sodium-coupled neutral amino acid transporter 318310302
Elimination half-life 0.5h
Carboplatin

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Information Structure
Name Carboplatin
Synonyms
1,1-Cyclobutanedicarboxylate Diammine Platinum(II)
Carboplatin
Carboplatine
Carboplatino
Carboplatinum
Cbdca
CCRIS 3404
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II)
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
Diammine(1,1-cyclobutanedicarboxylato)platinum (II)
Diammine-1,1-cyclobutane Dicarboxylate Platinum II
EINECS 255-446-0
HSDB 6957
JM 8
NSC 201345
NSC-241240
Paraplatin
Platinum (II), (1,1-cyclobutanedicarboxylato)diammine-, Cis-
Platinum(II), (1,1-cyclobutanedicarboxylato)diammine-, Cis-
ATC L01XA02
CID 38904
CAS 041575944
Drugbank ID DB00958
SMILES N.N.O=C1O[Pt]OC(=O)C12CCC2
Formula C6H14N2O4Pt
Molweight 373.264
Atoms 13
LogP 0.9712
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
3A4Inducer 11488523
Transporter
AC-No.NameReferences
O15244Solute carrier family 22 member 216242669
O15245Solute carrier family 22 member 120858838
O15431High affinity copper uptake protein 115634647
O15432Probable low affinity copper uptake protein 2 20930109
P08183Multidrug resistance protein 110433011
P19634SLC9A1 20841472
P33527Multidrug resistance-associated protein 111687904
P35670Wilson disease-associated protein17978167
P46059Intestinal H(+)/peptide cotransporter16253763
P55011Solute carrier family 12 member 218769031
Q86UG4Organic anion-transporting polypeptide 6A1 8068032
Q92887ATP-binding cassette sub-family C member 29571149
Q99624Sodium-coupled neutral amino acid transporter 318310302
Extrarenal fraction 0.15
Elimination half-life 3.8h
Oxaliplatin

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Information Structure
Name Oxaliplatin
Synonyms
(SP-4-2-(1R-trans))-(1,2-Cyclohexanediamine-N,N)(ethanedioato(2-)-O,O)platinum
1-OHP
Eloxatin
JM-83
NSC 266046
Oxalato(1R,2R-cyclohexanediammine)platinum(II)
Oxalato(trans-(-)-1,2-cyclohexanediamine)platinum(II)
Oxalato(trans-1-1,2-cyclohexanediamine)platinum(II)
Oxalatoplatin
Oxalatoplatinum
Oxaliplatin
Oxaliplatino
Oxaliplatinum
Oxaloplatine
Oxaloplatino
RP 54780
SR 96669
ATC L01XA03
CID 9887054
CAS 061825943
TTD Drug ID DAP000062
SMILES N[C@@H]1CCCC[C@H]1N
Formula C8H14N2O4Pt
Molweight 397.286
Atoms 15
LogP -1.9007
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
1A1Substrate 14646291
17498780
15016593
1A2Substrate 17498780
15016593
1B1Substrate 17498780
15016593
2E1Substrate 14646291
17498780
Transporter
AC-No.NameReferences
O15244Solute carrier family 22 member 220551056
Q04656Copper-transporting ATPase 115607932
Q86UG4SLCO6A115386340
Elimination half-life 12.0min
Satraplatin

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Information Structure
Name satraplatin
Synonyms
129580-63-8
bis-acetatoamminedichlorocyclohexylamine Platinum(iv)
bms-182751
bmy-45594
c081294
cid6918220
d05807
jm 216
jm-216
jm216
platinum, Bis(acetato-o)amminedichloro(cyclohexanamine)-, (oc-6-43)-
satraplatin
satraplatin (usan/inn)
yhi-601
ATC L01XA04
CID 6918220
CAS cid6918220
Formula C8H14N2O4Pt
Molweight 397.286
Atoms 15
LogP -1.9007
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 6
Transporter
AC-No.NameReferences
O15244Solute carrier family 22 member 220551056
Q04656Copper-transporting ATPase 115607932
Q86UG4SLCO6A115386340