Compound - Results

Clofazimine

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Information Structure
Name Clofazimine
Synonyms
2-Phenazinamine, 3,5-dihydro-N,5-bis(4-chlorophenyl)-3-((1-methylethyl)imino)-
3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine
3-(p-Chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin
3-(p-Chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine
4-25-00-03033 (Beilstein Handbook Reference)
B 663 (Pharmaceutical)
B 663 (VAN)
B-663
BRN 0060420
Chlofazimine
Clofazimina
Clofazimine
Clofaziminum
DRG-0067
EINECS 217-980-2
G 30320
Lampren
Lamprene
NSC-141046
Phenazine, 2,10-dihydro-3-(p-chloroanilino)-10-(p-chlorophenyl)-2-(isopropylimino)-
ATC J04BA01
CID 2794
CAS 002030639
TTD Drug ID DAP000789
SMILES CC(C)N=C1/C=C2N(C3=CC=C(Cl)C=C3)C4=C(C=CC=C4)N=C2C=C1NC5=CC=C(Cl)C=C5
Formula C27H22Cl2N4
Molweight 473.396
Atoms 33
LogP 7.6112
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
3A4Substrate Inhibitor 10923859
11996015
umm
Extrarenal fraction 1
Elimination half-life 240h
Dapsone

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Information Structure
Name Dapsone
Synonyms
1,1-Sulfonylbis(4-aminobenzene)
1,1-Sulphonylbis(4-aminobenzene)
1358F
4,4-Dapsone
4,4-Diaminodifenylsulfon
4,4-Diaminodiphenyl Sulfone
4,4-Diaminodiphenyl Suphone
4,4-Sulfonylbisaniline
4,4-Sulfonylbisbenzamine
4,4-Sulfonylbisbenzenamine
4,4-Sulfonyldianiline
4,4-Sulphonylbisbenzamine
4,4-Sulphonylbisbenzenamine
4,4-Sulphonyldianiline
4-13-00-01306 (Beilstein Handbook Reference)
4-Aminophenyl Sulfone
AI3-08087
Aniline, 4,4-sulfonyldi-
Araldite HT 976
Avlosulfon
Avlosulfone
Avlosulphone
Benzenamine, 4,4-sulfonylbis-
Bis(4-aminophenyl) Sulfone
Bis(4-aminophenyl)sulphone
Bis(p-aminophenyl) Sulfone
Bis(p-aminophenyl)sulphone
BRN 0788055
CCRIS 192
Croysulfone
Croysulphone
DADPS
Dapson
Dapsona
Dapsone
Dapsonum
DDS
DDS (pharmaceutical)
Di(4-aminophenyl) Sulfone
Di(4-aminophenyl)sulfone
Di(4-aminophenyl)sulphone
Di(p-aminophenyl) Sulfone
Di(p-aminophenyl)sulphone
Diamino-4,4-diphenyl Sulfone
Diamino-4,4-diphenyl Sulphone
Diaminodifenilsulfona
Diaminodiphenyl Sulfone
Diaphenylsulfon
Diaphenylsulfone
Diaphenylsulphon
Diaphenylsulphone
Diphenasone
Diphone
Disulone
DRG-0036
DSS
DSS (VAN)
Dubronax
Dumitone
EINECS 201-248-4
Eporal
F 1358
Hardener HT 976
HSDB 5073
HT 976
HY 976
Metabolite C
N,N-Diphenyl Sulfondiamide
NCI-C01718
Novophone
NSC 6091D
NSC-6091
p,p-Diaminodiphenyl Sulfone
p,p-Diaminodiphenyl Sulphone
p,p-Sulfonylbisbenzamine
p,p-Sulfonylbisbenzenamine
p,p-Sulfonyldianiline
p,p-Sulphonylbisbenzamine
p,p-Sulphonylbisbenzenamine
p,p-Sulphonyldianiline
p-Aminophenyl Sulfone
Sulfadione
Sulfona
Sulfona-Mae
Sulfone UCB
Sulfone, Diphenyl, 4,4-diamino-
Sulphadione
Sulphonyldianiline
Sumicure S
Tarimyl
Udolac
WR 448
ATC J04BA02
D10AX05
CID 2955
CAS 000080080
Drugbank ID DB00250
TTD Drug ID DAP000637
SMILES NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(N)C=C2
Formula C12H12N2O2S
Molweight 248.301
Atoms 17
LogP 3.927
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
2C8Substrate 10901692
10901692
2C9Substrate Inducer 10901692
9521735
10901692
11408370
9521735
12559973
15130760
2C18Substrate 10901692
2C19Substrate umm
10901692
2E1Substrate 7586950
10901692
7586950
7586950
3A4Substrate medicine.iupui.edu/flockhart
8742227
3A5Substrate medicine.iupui.edu/flockhart
3A7Substrate medicine.iupui.edu/flockhart
Extrarenal fraction 0.9
Elimination half-life 12-48 h
Aldesulfone Sodium

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Information Structure
Name Aldesulfone sodium
Synonyms
(Sulfonylbis(p-phenyleneimino))dimethanesulfinic Acid Disodium Salt
4:4-Diaminodiphenylsulfone Disodium Formaldehyde Sulfoxylate
Adesulfone Sodium
AI3-23947
Aldapsone
Aldesulfona Sodica
Aldesulfone Sodique
Aldesulfone Sodium
Aldesulfonum Natricum
Aniline, 4,4-sulfonyldi-, Bis(sodium Formaldehydesulfonylate)
Aniline, 4,4-sulfonyldi-, Bis(sodium Formaldehydesulfoxylate)
Diamidin
Diasone
Diasone Sodium Enterab
Diazon
Disodium (sulfonylbis(p-phenyleneimino))dimethanesulfinate
Disodium (sulfonylbis(p-phenylenimino))dimethanesulfinate
Disodium Diformaldehydesulfoxylate
Disodium Formaldehyde Sulfoxylate Diamino Diphenylsulfone
Disodium Formaldehydesulfoxylate-diaminodiphenylsulfone
Novotrone
NSC 27222
Sodium Aldesulphone
Sodium Sulfoxone
Sulfoxone Sodium
ATC J04BA03
CID 5351
CAS 000144752
Drugbank ID DB01145
TTD Drug ID DAP001192
SMILES [O-]S(=O)CNC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(NCS([O-])=O)C=C2
Formula C14H16N2O6S3
Molweight 404.482
Atoms 25
LogP 4.6598
Rotatable Bonds 8
H-Bond Donors 0
H-Bond Acceptors 8