Compound - Results

Cefalexin

Java required.


Information Structure
Name Cefalexin
Synonyms
(6R,7R)-7-((R)-2-Amino-2-phenylacetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure
7-(D-2-Amino-2-phenylacetamido)-3-methyl-delta (sup 3)-cephem-4- Carboxylic Acid
7-(D-2-Amino-2-phenylacetamido)-3-methyl-delta3-cephem-4-carboxylic Acid
7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic Acid
7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic Acid
Alcephin
Alexin
Alsporin
Biocef
BRN 0965503
Carnosporin
Cefa-iskia
Cefablan
Cefadal
Cefadin
Cefadina
Cefaleksin
Cefalessina
Cefalexin
Cefalexina
Cefalexine
Cefalexinum
Cefalin
Cefaloto
Cefaseptin
Cefax
Ceforal
Cefovit
Celexin
Cepastar
Cepexin
Cephacillin
Cephalexin
Cephalexine
Cephalexinum
Cephanasten
Cephaxin
Cephin
Cepol
Ceporex
Ceporex Forte
Ceporexin
Ceporexin-E
Ceporexine
Check
Cophalexin
Durantel
Durantel DS
Ed A-Ceph
EINECS 239-773-6
Erocetin
Factagard
Felexin
Fexin
HSDB 3022
Ibilex
Ibrexin
Inphalex
Kefalospes
Keflet
Keflex
Kefolan
Keforal
Kekrinal
Kidolex
L-Keflex
Lafarine
Larixin
Lenocef
Lexibiotico
Lilly 66873
Lonflex
Lopilexin
Madlexin
Mamalexin
Mamlexin
Medoxine
Neokef
Neolexina
Novolexin
Nufex
Oracef
Oriphex
Oroxin
Ortisporina
Ospexin
Palitrex
Pectril
Pyassan
Roceph
Roceph Distab
S 6437
Sanaxin
Sartosona
Sencephalin
Sepexin
Servispor
Sialexin
Sinthecillin
Sporicef
Sporidex
SQ 20248
Syncl
Syncle
Synecl
Tepaxin
Tokiolexin
Uphalexin
Voxxim
Winlex
Zozarine
ATC J01DB01
CID 2666
CAS 015686712
Drugbank ID DB00567
SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)C3=CC=CC=C3)C2=O)C(O)=O
Formula C16H17N3O4S
Molweight 347.389
Atoms 24
LogP 1.9234
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
2D6Substrate 15289959
3A4Substrate 10496649
Transporter
AC-No.NameReferences
P46059Solute carrier family 15 member 112356285
Q96FL8MATE-120484555
Extrarenal fraction 0.04
Elimination half-life 1h
Cefaloridine

Java required.


Information Structure
Name Cefaloridine
Synonyms
(6R,7R)-1-((2-Carboxy-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)pyridinium Hydroxide, Inner Salt
1-((7-beta-(2-(2-Thienyl)acetamido)-8-oxo-1-aza-5-thiabicyclo(4.2.0)-oct-2-en-3-yl)methyl)pyridinium-2-carboxylate
40602
7-((2-Thienyl)acetamido)-3-(1-pyridylmethyl)cephalosporanic Acid
7-(alpha-(2-Thienyl)acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic Acid Betaine
7-(Thiophene-2-acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic Acid Betaine
Aliporina
Ampligram
Betaine Cephaloridine
Cefaloridin
Cefaloridina
Cefaloridine
Cefaloridinum
Cefalorizin
Ceflorin
Cepaloridin
Cepalorin
CEPH 87/4
Cephaloridin
Cephaloridine
Cephaloridinum
Ceporan
Ceporin
Ceporine
CER
Cilifor
Deflorin
EINECS 200-052-6
Faredina
Floridin
Glaxoridin
HSDB 3023
Intrasporin
Keflodin
Keflordin
Kefloridin
Kefspor
Lilly 40602
Lloncefal
Loridine
N-(7-((2-Thienyl)acetamido)ceph-3-em-3-ylmethyl)pyridinium-4-carboxylate
N-(7-(2-Thienylacetamidoceph-3-ylmethyl))-pyridinium-2-carboxylate
Pyridinium, 1-((2-carboxy-8-oxo-7-((2-thienylacetyl)amino)-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, Hydroxide, Inner Salt, (6R-trans)-
Sch 11527
Sefacin
ATC J01DB02
CID 5773
CAS 000050599
SMILES [O-]C(=O)C1=C(CS[C@@H]2[C@H](NC(=O)CC3=CC=CS3)C(=O)N12)C[N+]4=CC=CC=C4
Formula C19H17N3O4S2
Molweight 415.486
Atoms 30
LogP 0.011
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 5
CYP interactions
NameRelationsReferences
2C8Substrate 15194707
Transporter
AC-No.NameReferences
P46059Solute carrier family 15 member 112356285
Q96FL8MATE-120484555
Cefalotin

Java required.


Information Structure
Name Cefalotin
Synonyms
3-(Acetoxymethyl)-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid
3-(Hydroxymethyl)-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid Acetate
3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic Acid
6R-trans-3-((Acetyloxy)methyl)-8-oxo-7-((2-thienylacetyl)amino)-5-thia-1-azabicyclo(4.2.0)-oct-2-ene-2-carboxylic Acid
7-(2-(2-Thienyl)acetylamido)cephalosporanic Acid
7-(2-Thienylacetamido)cephalosporanic Acid
7-(Thiophene-2-acetamido)cephalosporanic Acid
7-(Thiophene-2-acetamido)cephalosporin
Averon-1
BRN 0945586
Cefalothin
Cefalotin
Cefalotina
Cefalotine
Cefalotinum
Cemastin
Cephalothin
Cephalothinum
Cephalotin
Coaxin
CT
EINECS 205-815-7
HSDB 3024
ATC J01DB03
CID 6024
CAS 000153617
Drugbank ID DB00456
TTD Drug ID DAP000155
SMILES CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CC3=CC=CS3)C2=O)C(O)=O
Formula C16H16N2O6S2
Molweight 396.438
Atoms 28
LogP 0.9211
Rotatable Bonds 8
H-Bond Donors 0
H-Bond Acceptors 7
Transporter
AC-No.NameReferences
P46059Solute carrier family 15 member 112356285
Q96FL8MATE-120484555
Cefazolin

Java required.


Information Structure
Name Cefazolin
Synonyms
(6R,7R)-3-(((5-Methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid
(6R-trans)-3-(((5-Methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(((1H-tetrazol-1-yl)acetyl)-amino)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxyli
7-(1-(1H-)-Tetrazolylacetamido)-3-(2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl)delta3-cephem-4-carboxylic Acid
BRN 4169371
Cefamezin
Cefazolin
Cefazolina
Cefazoline
Cefazolinum
Cephamezine
Cephazolidin
Cephazolin
Cephazoline
CEZ
EINECS 247-362-8
Elzogram
HSDB 3213
ATC J01DB04
CID 33255
CAS 025953199
SMILES CC1=NN=C(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)CN4C=NN=N4)C3=O)C(O)=O)S1
Formula C14H14N8O4S3
Molweight 454.507
Atoms 31
LogP -0.3073
Rotatable Bonds 8
H-Bond Donors 0
H-Bond Acceptors 10
Transporter
AC-No.NameReferences
Q4U2R8hOAT114984259
Q8TCC7Solute carrier family 22 member 814984259
Extrarenal fraction 0.06
Elimination half-life 2h
Cefadroxil

Java required.


Information Structure
Name Cefadroxil
Synonyms
BL-S 578
Cefadroxil
Cefadroxil Anhydrous
Cefadroxilo
Cefadroxilum
Cephadroxil
D-Cefadroxil
EINECS 256-555-6
Oracefal
S 578
S-578
ATC J01DB05
CID 2610
CAS 050370122
TTD Drug ID DAP000446
SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)C3=CC=C(O)C=C3)C2=O)C(O)=O
Formula C16H17N3O5S
Molweight 363.388
Atoms 25
LogP 1.1796
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 7
Transporter
AC-No.NameReferences
P46059Peptide transporter 112356285
Q16348Kidney H(+)/peptide cotransporter14600253
Extrarenal fraction 0.1
Elimination half-life 1.4h
Cefazedone

Java required.


Information Structure
Name Cefazedone
Synonyms
BRN 1097746
Cefazedona
Cefazedone
Cefazedonum
Refosporene
ATC J01DB06
CID 71736
CAS 056187474
SMILES CC1=NN=C(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)CN4C=C(Cl)C(=O)C(Cl)=C4)C3=O)C(O)=O)S1
Formula C18H15Cl2N5O5S3
Molweight 548.443
Atoms 33
LogP 2.1747
Rotatable Bonds 8
H-Bond Donors 0
H-Bond Acceptors 8
Transporter
AC-No.NameReferences
P46059Peptide transporter 112356285
Q16348Kidney H(+)/peptide cotransporter14600253
Cefatrizine

Java required.


Information Structure
Name Cefatrizine
Synonyms
(6R,7R)-7-((R)-2-Amino-2-(p-hydroxyphenyl)acetamido)-8-oxo-3-((v-triazol-4-ylthio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid
Antibiotic BL-S 640
BL-S 640
BLS 640
Cefatrizine
Cefatrizino
Cefatrizinum
Cephatriazine
EINECS 257-324-2
S 640P
SKF 60771
ATC J01DB07
CID 40073
CAS 051627146
SMILES N[C@@H](C(=O)N[C@H]1[C@H]2SCC(CSC3=CNN=N3)=C(N2C1=O)C(O)=O)C4=CC=C(O)C=C4
Transporter
AC-No.NameReferences
P46059Peptide transporter 112356285
Q16348Kidney H(+)/peptide cotransporter14600253
Cefapirin

Java required.


Information Structure
Name Cefapirin
Synonyms
(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure
3-(Hydroxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamidol-5-thia-1-azabicyclo(4.2.0)oct-2-en-2carbonsaeure Acetat
7-(2-(4-Pyridylthio)acetamido)cephalosporanic Acid
BRN 1095157
Cefapirin
Cefapirina
Cefapirine
Cefapirinum
Cefaprin
Cephalosporanic Acid, 7-(2-(4-pyridylthio)acetamido)-
Cephapirin
Cephapirine
EINECS 244-466-5
HSDB 3215
ATC J01DB08
CID 30699
CAS 021593237
Drugbank ID DB01139
TTD Drug ID DAP001160
SMILES CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSC3=CC=NC=C3)C2=O)C(O)=O
Formula C17H17N3O6S2
Molweight 423.463
Atoms 30
LogP 0.8042
Rotatable Bonds 9
H-Bond Donors 0
H-Bond Acceptors 8
Transporter
AC-No.NameReferences
P46059Peptide transporter 112356285
Q16348Kidney H(+)/peptide cotransporter14600253
Cefradine

Java required.


Information Structure
Name Cefradine
Synonyms
(6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((amino-1,4-cyclohexadien-1-ylacetyl)amino)-3-methyl-8-oxo-, (6R-(6alpha,7beta(R*)))-
7-(D-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)-oct-2-ene-2-caboxylic Acid
7-(D-2-Amino-2-(1,4-cyclohexadienyl)acetamide)desacetoxycephalosporanicacid
Anspor
BRN 6075388
Cefradina
Cefradine
Cefradinum
Cephradin
Cephradine
EINECS 254-137-8
Eskacef
HSDB 3216
Sefril
SKF D 39304
SQ 11436
Velosef
ATC J01DB09
CID 38103
CAS 038821533
Drugbank ID DB01333
TTD Drug ID DAP000454
SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)C3=CCC=CC3)C2=O)C(O)=O
Formula C16H19N3O4S
Molweight 349.405
Atoms 27
LogP 1.3777
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 6
Transporter
AC-No.NameReferences
P46059Solute carrier family 15 member 115176063
Cefacetrile

Java required.


Information Structure
Name Cefacetrile
Synonyms
(6R,7R)-3-Acetoxymethyl-7-(2-cyanacetamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure
7-(2-Cyanacetamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carboxylat Acetat (ester)
7-Cyanacetylamino-cephalosporansaeure
Cefacetrile
Cefacetrilo
Cefacetrilum
EINECS 233-508-8
ATC J01DB10
CID 91562
CAS 010206210
Drugbank ID DB01414
TTD Drug ID DAP001172
SMILES CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CC#N)C2=O)C(O)=O
Formula C13H13N3O6S
Molweight 339.324
Atoms 23
LogP -0.46942
Rotatable Bonds 7
H-Bond Donors 0
H-Bond Acceptors 8
Transporter
AC-No.NameReferences
P46059Solute carrier family 15 member 115176063
Cefroxadine

Java required.


Information Structure
Name Cefroxadine
Synonyms
(6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methoxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid
7-(D-2-Amino-2-(1,4-cyclohexadienyl)acetamide)-3-methoxy-3-cephem-4-carboxylic Acid
Antibiotic CGP 9000
BRN 0587499
Cefroxadin
Cefroxadine
Cefroxadino
Cefroxadinum
Cgp 9000
CXD
EINECS 257-391-8
Oraspor
ATC J01DB11
CID 40117
CAS 051762051
SMILES COC1=C(N2[C@@H](SC1)[C@@H](NC(=O)[C@H](N)[C@H]3C=CCC=C3)C2=O)C(O)=O
Transporter
AC-No.NameReferences
P46059Solute carrier family 15 member 115176063
Ceftezole

Java required.


Information Structure
Name Ceftezole
Synonyms
Ceftezol
Ceftezole
Ceftezolum
CG-B 3 Q
ATC J01DB12
CID 65755
CAS 026973240
SMILES OC(=O)C1=C(CS[C@@H]2[C@H](NC(=O)CN3C=NN=N3)C(=O)N12)CSC4=NN=CS4
Formula C13H12N8O4S3
Molweight 440.481
Atoms 28
LogP -0.6157
Rotatable Bonds 8
H-Bond Donors 0
H-Bond Acceptors 10
Transporter
AC-No.NameReferences
P46059Solute carrier family 15 member 115176063