Compound - Results

Clotrimazole

Java required.


Information Structure
Name Clotrimazole
Synonyms
(2-Chlorophenyl)diphenyl-1-imidazolylmethane
(Chlorotrityl)imidazole
1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole
1-((o-Chloro-phenyl)diphenylmethyl)imidazole
1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole
1-(o-Chloro-alpha,alpha-diphenylbenzyl)imidazole
1-(o-Chlorophenyldiphenylmethyl)imidazole
1-(o-Chlorotrityl)imidazole
1H-Imidazole, 1-((2-chlorophenyl)diphenylmethyl)-
5-23-04-00291 (Beilstein Handbook Reference)
B 5097
BAY 5097
BAY B 5097
Bay-B 5097
Bis-fenil-(2-clorofenil)-1-imidazolil-metano
Bis-phenyl-(2-chlorophenyl)(1-imidazoyl)methane
Bisphenyl-(2-chlorphenyl)-1-imidazolyl-methan
BRN 0622318
Canesten
Canestine
CCRIS 6245
Chlotrimazole
Clotrimazol
Clotrimazole
Clotrimazolum
Desamix F
Diphenyl(2-chlorophenyl)(1-imidazolyl)methane
Diphenyl-(2-chlorophenyl)-1-imidazolylmethane
DRG-0072
EINECS 245-764-8
Empecid
FB 5097
Fem Care
Gyne Lotrimin
Gyne-Lotrimin
HSDB 3266
Lotrimin
Lotrimin AF Cream
Lotrimin AF Jock-Itch Cream
Lotrimin AF Solution
Methane, Bis-phenyl-(2-chlorophenyl)-1-imidazolyl-
Mycelex
Mycelex 7
Mycelex G
Mycelex OTC
Mycelex Troches
Mycosporin
Mykosporin
NSC 257473
Trimysten
Veltrim
ATC A01AB18
D01AC01
G01AF02
CID 2812
CAS 023593751
Drugbank ID DB00257
TTD Drug ID DAP000138
SMILES ClC1=C(C=CC=C1)C(N2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4
Formula C22H17ClN2
Molweight 344.837
Atoms 25
LogP 5.3767
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Inhibitor umm
2A6Inhibitor Inducer 1472091
umm
9143352
2B6Inhibitor Inducer umm
14977870
2C8Inhibitor 11136296
11136296
15601807
2C9Inhibitor 11996015
2C19Inhibitor umm
2D6Inhibitor umm
2E1Inhibitor umm
9574817
15135088
3A4Inhibitor Inducer 12867495
umm
12538830
15135088
3A7Inducer 12673034
11B1Inhibitor 7663533
19AInhibitor 15554355
Transporter
AC-No.NameReferences
P33527Leukotriene C(4) transporter11737211
Q92887Canalicular multispecific organic anion transporter 111836020
Miconazole

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Information Structure
Name Miconazole
Synonyms
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
5-23-04-00320 (Beilstein Handbook Reference)
BRN 0965511
CCRIS 7924
Daktarin IV
EINECS 245-324-5
Miconazol
Miconazole
Miconazolo
Miconazolum
MJR 1762
Monistat IV
NSC 170986
R 18134
ATC A01AB09
A07AC01
D01AC02
G01AF04
J02AB01
S02AA13
CID 4189
CAS 022916478
Drugbank ID DB01110
TTD Drug ID DAP000154
SMILES ClC1=CC=C(CO[C@H](CN2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C(Cl)=C1
Formula C18H14Cl4N2O
Molweight 416.129
Atoms 25
LogP 6.4548
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
1A2Inhibitor 16141569
16141569
2A6Inhibitor 9143352
2B6Inhibitor 11854151
2C9Inhibitor 16141567
10945865
10709776
16141567
2C19Inhibitor 16141567
11854151
16141567
2D6Inhibitor 11854151
16141569
16141569
2E1Inhibitor 16141569
16141569
3A4Substrate Inhibitor 15135088
11996015
11B1Inhibitor 7663533
19AInhibitor 15554355
Transporter
AC-No.NameReferences
P33527Leukotriene C(4) transporter11737211
Q92887Canalicular multispecific organic anion transporter 111836020
Extrarenal fraction 1
Elimination half-life 24h
Econazole

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Information Structure
Name Econazole
Synonyms
(+-)-Econazole
1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole
5-23-04-00320 (Beilstein Handbook Reference)
BRN 0964150
Econazol
Econazole
Econazolum
Ecostatin
EINECS 248-341-6
NSC 187789
ATC D01AC03
G01AF05
CID 3198
CAS 027220479
Drugbank ID DB01127
TTD Drug ID DAP001269
SMILES ClC1=CC=C(CO[C@@H](C[C@H]2C=NC=N2)C3=C(Cl)C=C(Cl)C=C3)C=C1
Formula C18H15Cl3N2O
Molweight 381.684
Atoms 24
LogP 5.8014
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
2E1Inhibitor 9574817
11996015
9574817
3A4Inhibitor 15135088
19AInhibitor 2222512
Transporter
AC-No.NameReferences
P33527Leukotriene C(4) transporter11737211
Q92887Canalicular multispecific organic anion transporter 111836020
Chlormidazole

Java required.


Information Structure
Name Chlormidazole
Synonyms
Chlormidazole
Chlormidazole
Chlormidazolum
Clomidazolum
ATC D01AC04
CID 71821
CAS 003689767
SMILES CC1=NC2=CC=CC=C2N1CC3=CC=C(Cl)C=C3
Formula C15H13ClN2
Molweight 256.73
Atoms 18
LogP 4.0464
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 1
Transporter
AC-No.NameReferences
P33527Leukotriene C(4) transporter11737211
Q92887Canalicular multispecific organic anion transporter 111836020
Isoconazole

Java required.


Information Structure
Name Isoconazole
Synonyms
1-(2,4-Dichloro-beta-((2,6-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2-(2,4-Dichlorophenyl)-2-((2,6-dichlorophenyl)methoxy)ethyl)1H-imidazole
EINECS 248-508-3
Isoconazol
Isoconazole
Isoconazolum
Travogen
ATC D01AC05
G01AF07
CID 3760
CAS 027523406
SMILES ClC1=CC(Cl)=C(C=C1)[C@H](CN2C=CN=C2)OCC3=C(Cl)C=CC=C3Cl
Formula C18H14Cl4N2O
Molweight 416.129
Atoms 25
LogP 6.4548
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
19AInhibitor 2222512
Transporter
AC-No.NameReferences
P33527Leukotriene C(4) transporter11737211
Q92887Canalicular multispecific organic anion transporter 111836020
Tiabendazole

Java required.


Information Structure
Name Tiabendazole
Synonyms
1H-Benzimidazole, 2-(4-thiazolyl)-
2-(1,3-Thiazol-4-yl)benzimidazole
2-(4-Thiazolyl)-1H-benzimidazole
2-(4-Thiazolyl)benzimidazole
2-Thiazole-4-ylbenzimidazole
4-(2-Benzimidazolyl)thiazole
AI3-50598
APL-luster
Benzimidazole, 2-(4-thiazolyl)-
Biogard
Bioguard
Bovizole
BRN 0611403
Captan T
Caswell No. 849A
CCRIS 4510
Chemviron TK 100
Cropasal
E-Z-Ex
EINECS 205-725-8
EPA Pesticide Chemical Code 060101
Eprofil
Equizole
Equizole A
G 491
Helmindrax Octelmin
Hokustar HP
HSDB 2027
Lombristop
Mertec
Mertect
Mertect 160
Metasol TK-100
Mintesol
Mintezol
Mintezole
Minzolum
MK 360
Mycozol
Nemapan
NSC 525040
Omnizole
Ormogal
Pitrizet
Polival
Rival
RPH
RTU Flowable Fungicide
Sanaizol 100
Sistesan
Storite
Syntol M100
Tbdz
TBZ
TBZ 60W
TBZ-6
Tebuzate
Tecto 10P
Tecto 40F
Tecto 60
Tecto RPH
Testo
Thiaben
Thiabendazol
Thiabendazole
Thiabendazolum
Thiabenzole
Thibenzol
Thibenzole
Thibenzole 200
Thibenzole ATT
Tiabenda
Tiabendazol
Tiabendazole
Tiabendazolum
Tobaz
Top Form Wormer
Triasox
ATC D01AC06
P02CA02
CID 5430
CAS 000148798
Drugbank ID DB00730
TTD Drug ID DAP000664
SMILES N1C2=C(C=CC=C2)N=C1C3=CSC=N3
Formula C10H7N3S
Molweight 201.248
Atoms 14
LogP 2.6864
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
1A1Inducer 10445394
9784250
9616189
7565906
7872687
8078896
8900397
1A2Substrate Inhibitor 9565779
9565779
11124226
Transporter
AC-No.NameReferences
P33527Leukotriene C(4) transporter11737211
Q92887Canalicular multispecific organic anion transporter 111836020
Tioconazole

Java required.


Information Structure
Name Tioconazole
Synonyms
(+-)-1-(2,4-Dichloro-beta-((2-chloro-3-ethenyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2-chloro-3-thenyl)-oxy)phenethyl)imidazole
5-23-04-00324 (Beilstein Handbook Reference)
BRN 0573867
EINECS 265-973-8
Tioconazol
Tioconazole
Tioconazolum
UK 20349
Vagistat-1
ATC D01AC07
G01AF08
CID 5482
CAS 065899732
Drugbank ID DB01007
TTD Drug ID DAP001268
SMILES ClC1=CC(Cl)=C(C=C1)[C@@H](CN2C=CN=C2)OCC3=C(Cl)SC=C3
Formula C16H13Cl3N2OS
Molweight 387.711
Atoms 23
LogP 5.8629
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
1A2Inhibitor 11854151
11854151
2C8Inhibitor umm
2C9Inhibitor umm
2C19Inhibitor 11854151
11854151
2E1Inhibitor 11854151
3A4Inhibitor 11854151
19AInhibitor 2222512
Transporter
AC-No.NameReferences
P33527Leukotriene C(4) transporter11737211
Q92887Canalicular multispecific organic anion transporter 111836020
Ketoconazole

Java required.


Information Structure
Name Ketoconazole
Synonyms
(+-)-cis-1-Acetyl-4-(p-((2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine
BRN 4303081
DRG-0073
EINECS 265-667-4
Fungarest
Fungoral
Ketoconazol
Ketoconazole
Ketoconazolum
Ketoderm
Ketoisdin
KW-1414
Nizoral
Orifungal M
Panfungol
R 41400
ATC D01AC08
G01AF11
J02AB02
CID 3823
CAS 065277421
SMILES CC(=O)N1CCN(CC1)C2=CC=C(OC[C@@H]3CO[C@](CN4C=CN=C4)(O3)C5=C(Cl)C=C(Cl)C=C5)C=C2
Formula C26H28Cl2N4O4
Molweight 531.431
Atoms 36
LogP 4.2087
Rotatable Bonds 8
H-Bond Donors 0
H-Bond Acceptors 5
CYP interactions
NameRelationsReferences
1A1Inhibitor Inducer 10821163
17283379
14709627
1A2Inhibitor umm
9351907
1B1Inhibitor 14709627
2A6Inhibitor umm
9143352
11978200
2B6Inhibitor 14709627
2C8Inhibitor 15373932
14709627
11038157
11136296
15601807
2C9Inhibitor 15373932
14709627
9764927
11854151
15618748
2C19Inhibitor 14709627
10192828
10383565
15618748
2D6Inhibitor umm
15618748
2E1Inhibitor 15027815
2F1Inhibitor 14709627
3A4Substrate Inhibitor Inducer 15821046
12817528
14712470
12624000
12072427
10048600
9616194
15180387
18082278
9616194
15618748
8690825
1371482
umm
3A5Substrate Inhibitor Inducer 17361128
8690825
1371482
12814972
15180387
18082278
9812178
3A7Inhibitor 8690825
1371482
4F2Inhibitor 16997912
11B1Inhibitor 7663533
51AInhibitor 15611056
Transporter
AC-No.NameReferences
P08183Multidrug resistance protein 118197554
P78381UDP-galactose translocator20939765
Q92887ATP-binding cassette sub-family C member 219070657
Q9UNQ0Breast cancer resistance protein17518356
Q9Y6L6Solute carrier organic anion transporter family member 1B121456052
Sulconazole

Java required.


Information Structure
Name Sulconazole
Synonyms
Sulconazol
Sulconazole
Sulconazolum
ATC D01AC09
CID 5318
CAS 061318909
SMILES ClC1=CC=C(CS[C@H](CN2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C=C1
Formula C18H15Cl3N2S
Molweight 397.749
Atoms 24
LogP 6.518
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Inhibitor 11854151
11854151
2A6Inhibitor umm
2B6Inhibitor 11854151
11854151
2C9Inhibitor 11854151
11854151
2C19Inhibitor 11854151
11854151
2D6Inhibitor 11854151
11854151
2E1Inhibitor umm
3A4Inhibitor umm
Transporter
AC-No.NameReferences
P08183Multidrug resistance protein 118197554
P78381UDP-galactose translocator20939765
Q92887ATP-binding cassette sub-family C member 219070657
Q9UNQ0Breast cancer resistance protein17518356
Q9Y6L6Solute carrier organic anion transporter family member 1B121456052
Bifonazole

Java required.


Information Structure
Name Bifonazole
Synonyms
(+-)-1-(p,alpha-Diphenylbenzyl)imidazole
1-((4-Biphenylyl)phenylmethyl)-1H-imidazole
1-(alpha-(4-Biphenylyl)benzyl)imidazole
1H-Imidazole, 1-((1,1-biphenyl)-4-ylphenylmethyl)-
5-23-04-00292 (Beilstein Handbook Reference)
BAY H 4502
Bifonazol
Bifonazole
Bifonazolum
BRN 0618427
EINECS 262-336-6
Mycospor
Trifonazole
ATC D01AC10
CID 2378
CAS 060628968
Drugbank ID DB04794
TTD Drug ID DAP000877
SMILES C1=CC=C(C=C1)[C@H](N2C=CN=C2)C3=CC=C(C=C3)C4=CC=CC=C4
Formula C22H18N2
Molweight 310.392
Atoms 24
LogP 5.1878
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
2C19Inhibitor PMID: 2634093
2E1Inhibitor 9574817
15135088
3A4Inhibitor 15135088
19AInhibitor 2222512
15554355
Transporter
AC-No.NameReferences
P08183Multidrug resistance protein 118197554
P78381UDP-galactose translocator20939765
Q92887ATP-binding cassette sub-family C member 219070657
Q9UNQ0Breast cancer resistance protein17518356
Q9Y6L6Solute carrier organic anion transporter family member 1B121456052
Oxiconazole

Java required.


Information Structure
Name Oxiconazole
Synonyms
2,4-Dichlor-O-(2,4-dichlorbenzyl)-2-(1-imidazolyl)-(Z)-acetophenonoxim
2,4-Dichloro-2-imidazol-1-ylacetophenone (Z)-(O-(2,4-dichlorobenzyl)oxime)
Oxiconazol
Oxiconazole
Oxiconazolum
Ro 13-8996
ATC D01AC11
G01AF17
CID 5353853
CAS 064211456
Drugbank ID DB00239
SMILES ClC1=CC(Cl)=C(CON=C(/CN2C=CN=C2)C3=C(Cl)C=C(Cl)C=C3)C=C1
Formula C18H13Cl4N3O
Molweight 429.127
Atoms 26
LogP 6.1178
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
3A4Inducer 17998298
Transporter
AC-No.NameReferences
P08183Multidrug resistance protein 118197554
P78381UDP-galactose translocator20939765
Q92887ATP-binding cassette sub-family C member 219070657
Q9UNQ0Breast cancer resistance protein17518356
Q9Y6L6Solute carrier organic anion transporter family member 1B121456052
Fenticonazole

Java required.


Information Structure
Name Fenticonazole
Synonyms
Fenticonazol
Fenticonazole
Fenticonazolum
ATC D01AC12
G01AF12
CID 51755
CAS 072479266
SMILES ClC1=CC=C([C@@H](CN2C=CN=C2)OCC3=CC=C(SC4=CC=CC=C4)C=C3)C(Cl)=C1
Formula C24H20Cl2N2OS
Molweight 455.399
Atoms 30
LogP 7.2992
Rotatable Bonds 8
H-Bond Donors 0
H-Bond Acceptors 2
Transporter
AC-No.NameReferences
P08183Multidrug resistance protein 118197554
P78381UDP-galactose translocator20939765
Q92887ATP-binding cassette sub-family C member 219070657
Q9UNQ0Breast cancer resistance protein17518356
Q9Y6L6Solute carrier organic anion transporter family member 1B121456052
Omoconazole

Java required.


Information Structure
Name Omoconazole
Synonyms
CM 8282
Omoconazol
Omoconazole
Omoconazolum
ATC D01AC13
G01AF16
CID 3033988
CAS 074512122
SMILES CC(N1C=CN=C1)=C(OCCOC2=CC=C(Cl)C=C2)C3=C(Cl)C=C(Cl)C=C3
Transporter
AC-No.NameReferences
P08183Multidrug resistance protein 118197554
P78381UDP-galactose translocator20939765
Q92887ATP-binding cassette sub-family C member 219070657
Q9UNQ0Breast cancer resistance protein17518356
Q9Y6L6Solute carrier organic anion transporter family member 1B121456052
Sertaconazole

Java required.


Information Structure
Name Sertaconazole
Synonyms
1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
7-Chloro-3-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy-methyl)benzo(b)thiophene
7-Cloro-3-(1-(2,4-diclorofenil)-2-(1H-imidazol-1-il)etoxi-metil)benzo(b)tiofeno
BRN 5385663
FI-7045
Sertaconazol
Sertaconazole
Sertaconazolum
ATC D01AC14
CID 65863
CAS 099592322
Drugbank ID DB01153
TTD Drug ID DAP001270
SMILES ClC1=CC(Cl)=C(C=C1)[C@@H](CN2C=CN=C2)OCC3=CSC4=C3C=CC=C4Cl
Formula C20H15Cl3N2OS
Molweight 437.77
Atoms 27
LogP 7.0161
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 2
CYP interactions
NameRelationsReferences
51AInhibitor fda
Transporter
AC-No.NameReferences
P08183Multidrug resistance protein 118197554
P78381UDP-galactose translocator20939765
Q92887ATP-binding cassette sub-family C member 219070657
Q9UNQ0Breast cancer resistance protein17518356
Q9Y6L6Solute carrier organic anion transporter family member 1B121456052
Fluconazole

Java required.


Information Structure
Name Fluconazole
Synonyms
2,4-Difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl Alcohol
2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)-2-propanol
Afungil
Alflucoz
alpha-(2,4-Difluorophenyl)-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol
Baten
Biocanol
Biozolene
Canzol
CCRIS 7211
Cryptal
Diflucan
Dimycon
DRG-0005
Elazor
Flucazol
Fluconazol
Fluconazole
Fluconazolum
Flukezol
Flunizol
Fluzone
Forcan
Fungata
Mutum
Oxifugol
Pritenzol
Syscan
Triflucan
UK 49858
Zemyc
Zonal
ATC D01AC15
J02AC01
CID 3365
CAS 086386734
Drugbank ID DB00196
TTD Drug ID DAP000628
SMILES OC(CN1C=NC=N1)(CN2C=NC=N2)C3=C(F)C=C(F)C=C3
Formula C13H12F2N6O
Molweight 306.271
Atoms 22
LogP 0.7358
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 7
CYP interactions
NameRelationsReferences
1A1Inducer 17283379
1A2Inhibitor umm
2C8Inhibitor umm
2C9Substrate Inhibitor 14747429
9551703
umm
10799653
10709776
11475469
10952477
2C18Inhibitor 15963096
2C19Inhibitor 10709776
umm
10709776
11475469
2D6Inhibitor 16984215
3A4Inhibitor Inducer umm
15692832
11475469
16406388
3A5Inhibitor Inducer 16172184
16822276
18220561
19889796
8520811
16406388
11B1Inhibitor 7663533
19AInhibitor 7709362
Phase2 interactions
NameReferences
UGT 20484152
Transporter
AC-No.NameReferences
P08183Multidrug resistance protein 118197554
P78381UDP-galactose translocator20939765
Q92887ATP-binding cassette sub-family C member 219070657
Q9UNQ0Breast cancer resistance protein17518356
Q9Y6L6Solute carrier organic anion transporter family member 1B121456052
Extrarenal fraction 0.2
Elimination half-life 30h
Flutrimazole

Java required.


Information Structure
Name Flutrimazole
Synonyms
1-((2-Fluorophenyl)(4-fluorophenyl)phenylmethyl)-1H-imidazole
1-(o-Fluoro-alpha-(p-fluorophenyl)-alpha-phenylbenzyl)imidazole
BRN 5383184
Flutrimazol
Flutrimazole
Flutrimazolum
UR-4056
ATC D01AC16
G01AF18
CID 3401
CAS 119006778
SMILES FC1=CC=C(C=C1)[C@@](N2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4F
Formula C22H16F2N2
Molweight 346.373
Atoms 26
LogP 5.0015
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 3
Transporter
AC-No.NameReferences
P08183Multidrug resistance protein 118197554
P78381UDP-galactose translocator20939765
Q92887ATP-binding cassette sub-family C member 219070657
Q9UNQ0Breast cancer resistance protein17518356
Q9Y6L6Solute carrier organic anion transporter family member 1B121456052