Compound - Results

Hydrocortisone

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Information Structure
Name Hydrocortisone
Synonyms
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11beta,17,21-Trihydroxypregn-4-ene-3,20-dione
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydroxycortisone
17-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
4-Pregnene-11beta,17alpha,21-triol-3,20-dione
Acticort
Aeroseb-HC
AI3-25006
Ala-Scalp
Alacort
Algicirtis
Amberin
Anflam
Anti-inflammatory Hormone
Aquacort
Aquanil HC
Barseb HC
Basan-Corti
CCRIS 5854
Cetacort
Clear Aid
Cleiton
Cobadex
Compound F (kendall)
Cort-Dome
Cortanal
Cortef
Cortenema
Cortesal
Corticreme
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol Alcohol
Cortisolonum
Cortisporin Otico
Cortispray
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Delacort
Derm-Aid
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Efcorbin
Efcortelan
EINECS 200-020-1
Eldecort
Eldercort
Epicort
Epiderm H
Esiderm H
Evacort
Ficortril
Foille Insetti
Genacort
Genacort (lotion)
Gyno-Cortisone
HC
Heb Cort
Heb-Cort
Hidalone
Hidro-colisona
Hidrocortisona
HSDB 3339
Hycort
Hycortol
Hycortole
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydrocorticosterone
Hydrocortisone
Hydrocortisone Alcohol
Hydrocortisone Free Alcohol
Hydrocortisonum
Hydrocortisyl
Hydrocortone
Hydroxycortisone
Hytisone
Hytone
Hytone Lotion
Idrocortisone
Incortin-H
Incortin-hydrogen
Kendalls Compound F
Komed HC
Kyypakkaus
Lacticare-HC
Lactisona
Lubricort
Maintasone
Meusicort
Mildison
Milliderm
Neosporin-H Ear
NSC 10483
Nutracort
Optef
Otosone-F
Penecort
Permicort
Polcort H
Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11-beta)-
Pregn-4-ene-3,20-dione, 11beta,17,21-trihydroxy-
Preparation H Hydrocortisone Cream
Prevex HC
Proctofoam
Rectoid
Reichsteins Substance M
Remederm HC
Sanatison
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stiefcorcil
Systral Hydrocort
Tarcortin
Texacort
Texacort Lotion 25
Timocort
Transderma H
Traumaide
Uniderm
ATC A01AC03
A07EA02
C05AA01
D07AA02
D07XA01
H02AB09
S01BA02
S01CB03
S02BA01
CID 3640
CAS 000050237
Drugbank ID DB00741
SMILES C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)C[C@H](O)[C@H]23
Formula C21H30O5
Molweight 362.46
Atoms 26
LogP 1.7816
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 5
CYP interactions
NameRelationsReferences
1B1Inhibitor 8674863
2C8Inducer 12031713
3A4Substrate Inhibitor Inducer 14715379
8068867
1554942
11996015
1302569
15726657
11471773
11318772
11206036
10829051
2590599
11996015
3A5Substrate 16141800
3A7Substrate 9644715
9644715
11B1Substrate 15356073
11B2Substrate 15356073
11996015
Phase2 interactions
NameReferences
GST 11788566
MET 571728
NAT 12168848
SUL 11454732,
19523470,
3192164
UGT 3123148,
16817017
Transporter
AC-No.NameReferences
P08183ATP-binding cassette sub-family B member 121182940
Q8TCC7Solute carrier family 22 member 816835396
Q9NRA2AST 194376
Extrarenal fraction 1
Elimination half-life 1.5h
Betamethason

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Information Structure
Name Betamethason
Synonyms
16-beta-Methyl-1,4-pregnadiene-9-alpha-fluoro-11-beta,17-alpha,21-triol-3,20-dione
4-08-00-03501 (Beilstein Handbook Reference)
9-alpha-Fluoro-16-beta-methyl-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione
9-alpha-Fluoro-16-beta-methylprednisolone
9-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
9-Fluoro-16beta-methylprednisolone
9alpha-Fluoro-16beta-methylprednisolone
Bebate
Becort
Bedifos
beta-Methasone
beta-Methasone Alcohol
Betacorlan
Betacortril
Betadexamethasone
Betafluorene
Betamamallet
Betametasona
Betametasone
Betamethason
Betamethasone
Betamethasone Alcohol
Betamethasone Cream
Betamethasonum
Betamethazone
Betapredol
Betasolon
Betnelan
Betsolan
BRN 3176546
Celestene
Celestone
Celestone Syrup And Tablets
Cidoten
Corticosterone, 1-dehydro-9-fluoro-17-hydroxy-16beta-methyl-
Desacort-beta
EINECS 206-825-4
Flubenisolone
Hormezon
HSDB 3015
Methazon
NSC-39470
Prednisolone, 9-fluoro-16beta-methyl-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16beta)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16beta-methyl-
Rinderon
Rinderon A
Sch 4831
Valisone
Visubeta
ATC A01AC05
A07EA04
C05AA05
D07AC01
D07XC01
H02AB01
R01AD06
R03BA04
S01BA06
S01CB04
S02BA07
S03BA03
CID 3003
CAS 000378449
Drugbank ID DB00443
SMILES C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
Formula C22H29FO5
Molweight 392.461
Atoms 28
LogP 1.8957
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 6
CYP interactions
NameRelationsReferences
3A4Inhibitor umm
19ASubstrate Inducer 10736248
3347052
Phase2 interactions
NameReferences
SUL 8894510
Transporter
AC-No.NameReferences
P08183ATP-binding cassette sub-family B member 121182940
Q8TCC7Solute carrier family 22 member 816835396
Q9NRA2AST 194376
Extrarenal fraction 0.95
Elimination half-life 6h
Fluorometholone

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Information Structure
Name Fluorometholone
Synonyms
9-Fluoro-11-beta,17-dihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
AI3-52813
Cortilet
Delmeson
EINECS 207-041-5
Flumetholon
Fluor-Op
Fluormetholone
Fluormetholonum
Fluoromethalone
Fluorometholone
Fluorometholonum
Fluorometolona
Fluorometolone
FML Forte
FML Liquifilm
FML S.O.P.
NSC 33001
Oxylone
Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17-dihydroxy-6-alpha-methyl-
Trilcin
U 8614
ATC C05AA06
D07AB06
D07XB04
D10AA01
S01BA07
S01CB05
CID 3384
CAS 000426131
Drugbank ID DB00324
SMILES C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]4(C)C=CC(=O)C=C14
Formula C22H29FO4
Molweight 376.462
Atoms 27
LogP 2.9233
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 5
Transporter
AC-No.NameReferences
P08183ATP-binding cassette sub-family B member 121182940
Q8TCC7Solute carrier family 22 member 816835396
Q9NRA2AST 194376
Fluocortolone

Java required.


Information Structure
Name Fluocortolone
Synonyms
6-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
6-alpha-Fluoro-16-alpha-methyl-1-dehydrocorticosterone
6-alpha-Fluoro-16-alpha-methyl-delta(sup 1,4)-pregnadiene-11-beta-diol-3,20-dione
6-alpha-Fluoro-16-alpha-methylpregna-1,4-diene-11-beta,21-diol-3,20-dione
6alpha-Fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
BRN 3122594
EINECS 205-811-5
Fluocortolon
Fluocortolona
Fluocortolone
Fluocortolonum
Fluorcortolone
Fluorocortolone
SH 742
Ultralan Oral
ATC C05AA08
D07AC05
D07XC05
H02AB03
CID 9053
CAS 000152976
SMILES C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO
Transporter
AC-No.NameReferences
P08183ATP-binding cassette sub-family B member 121182940
Q8TCC7Solute carrier family 22 member 816835396
Q9NRA2AST 194376
Extrarenal fraction 1
Elimination half-life 1.3h
Fluocinolone Acetonide

Java required.


Information Structure
Name Fluocinolone acetonide
Synonyms
6-alpha,9-alpha-Difluoro-16-alpha-hydroxyprednisolone 16,17-acetonide
6alpha,9-Difluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, Cyclic 16,17-acetal With Acetone
6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide
6alpha-Fluorotriamcinolone Acetonide
Acetonida De Fluocinolona
Acetonide De Fluocinolone
CCRIS 3250
Dermalar
EINECS 200-668-5
Flucinar
Flucort
Fluocinolonacetonidum
Fluocinolone 16,17-acetonide
Fluocinolone Acetonide
Fluocinoloni Acetonidum
Fluonid
Fluovitif
Flupollon
HSDB 3083
Jellin
Localyn
Localyn Syntex
NSC 92339
Omniderm
Percutina
Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-
Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxy-, Cyclic 16,17-acetal With Acetone
Radiocin
RS-1401 AT
Sinalar
Synalar
Synalar-HP
Synamol
Synandone
Synandrone
Synemol
Synotic
Synsac
Tefunote
ATC C05AA10
D07AC04
S01BA15
S02BA08
CID 3381
CAS 000067732
Drugbank ID DB00591
SMILES CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
Formula C24H30F2O6
Molweight 452.488
Atoms 32
LogP 2.3668
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 8
Transporter
AC-No.NameReferences
P08183ATP-binding cassette sub-family B member 121182940
Q8TCC7Solute carrier family 22 member 816835396
Q9NRA2AST 194376
Fluocinonide

Java required.


Information Structure
Name Fluocinonide
Synonyms
6alpha,9-Difluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, Cyclic 16,17-acetal With Acetone, 21-acetate
Bestasone
Biscosal
Cortalar
EINECS 206-597-6
Flucinar
Fluocinolide
Fluocinolide Acetate
Fluocinolone Acetonide 21-acetate
Fluocinolone Acetonide Acetate
Fluocinonide
Fluocinonido
Fluocinonidum
Fluzon
Lidex
Lidex E
Metosyn
NSC 101791
Straderm
Synalar Acetate
Topsymin
Topsyn
ATC C05AA11
D07AC08
CID 3382
CAS 000356127
Drugbank ID DB01047
SMILES CC(=O)OCC(=O)[C@@]12OC(C)(C)O[C@@H]1C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]23C
Formula C26H32F2O7
Molweight 494.525
Atoms 35
LogP 2.9376
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 9
Transporter
AC-No.NameReferences
P08183ATP-binding cassette sub-family B member 121182940
Q8TCC7Solute carrier family 22 member 816835396
Q9NRA2AST 194376
Triamcinolone

Java required.


Information Structure
Name Triamcinolone
Synonyms
11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione
4-08-00-03629 (Beilstein Handbook Reference)
9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-16-alpha-hydroxyprednisolone
9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-Fluoro-16alpha-hydroxyprednisolone
Adcortyl
Aristocort
Aristocort Tablets
BRN 2341955
Celeste
Cinolone-T
CL 19823
Delphicort
EINECS 204-718-7
Fluoxyprednisolone
HSDB 3194
Kenacort
Kenacort-AG
Ledercort
NSC 13397
Omcilon
Orion
Polcortolon
Prednisolone, 9-fluoro-16alpha-hydroxy-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11-beta,16-alpha)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy-
Rodinolone
SK-Triamcinolone
Tiamcinolonum
Triam-Tablinen
Triamcet
Triamcinlon
Triamcinolon
Triamcinolona
Triamcinolone
Triamcinolonum
Tricortale
Volon
ATC A01AC01
D07AB09
D07XB02
H02AB08
R01AD11
R03BA06
S01BA05
C05AA12
CID 31307
CAS 000124947
Drugbank ID DB00620
TTD Drug ID DAP000417
SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
Formula C21H27FO6
Molweight 394.434
Atoms 32
LogP 0.6205
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 7
CYP interactions
NameRelationsReferences
3A4Inducer 10570047
3A5Inducer 10570047
3A7Inducer 10570047
Phase2 interactions
NameReferences
SUL 8894510,
11454732
Transporter
AC-No.NameReferences
P08183ATP-binding cassette sub-family B member 121182940
Q8TCC7Solute carrier family 22 member 816835396
Q9NRA2AST 194376
Extrarenal fraction 1
Elimination half-life 1.5h