Compound - Results

Amiloride

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Information Structure
Name Amiloride
Synonyms
Amilorida
Amiloride
Amiloridum
Amipramidin
Amipramizid
CCRIS 6545
EINECS 220-024-7
Guanamprazin
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide
N-Amidino-3,5-diamino-6-chlorpyrazincarboxamid
ATC C03DB01
CID 16231
CAS 002609463
Drugbank ID DB00594
TTD Drug ID DAP000187
SMILES NC(=N)NC(=O)C1=NC(Cl)=C(N)N=C1N
Formula C6H8ClN7O
Molweight 229.627
Atoms 15
LogP 1.271
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 8
CYP interactions
NameRelationsReferences
1A1Inhibitor 15081870
Transporter
AC-No.NameReferences
C7EWH7Sodium transporter6320883
O15244Solute carrier family 22 member 216394027
O15245Solute carrier family 22 member 111708789
P19634SLC9A1 16831598
Q9UBY0Sodium/hydrogen exchanger 2 8512555
Extrarenal fraction 0.25
Elimination half-life 9.6h
Triamterene

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Information Structure
Name Triamterene
Synonyms
2,4,7-Pteridinetriamine, 6-phenyl-
2,4,7-Triamino-6-fenilpteridina
2,4,7-Triamino-6-phenylpteridine
5-26-17-00447 (Beilstein Handbook Reference)
6-Phenyl-2,4,7-pteridinetriamine
6-Phenyl-2,4,7-triaminopteridine
Ademin
Ademin(e)
Ademine
AI3-60017
Amteren
Anjal
Apo-triazide
BRN 0266723
CCRIS 5872
Dazid
Diarol
Dinazide
Diren
Ditak
Diucelpin
Diurene
Diutensat
Diuteren
Dyberzide
Dyren
Dyrenium
Dytac
Dytenzide
EINECS 206-904-3
Esiteren
Fluss 40
Hidiurese
HSDB 3405
Hydrene
Hypertorr
Isobar
Jatropur
Jenateren
Kalspare
Masuharmin
NCI C56042
Nephral
Noridil
Noridyl
NSC 77625
Pteridine, 2,4,7-triamino-6-phenyl-
Pterofen
Pterophene
Renezide
Reviten
SALI-PUREN
SK&F 8542
SKF 8542
Taturil
Teriam
Teridin
Thiazid Wolff
Tri-Span
Triamizide
Triampur
Triamteren
Triamterena
Triamterene
Triamterenum
Triamteril
Triamteril Complex
Triamthiazid
Triazide
Tricilone
Trispan
Triteren
Triurene
Trizid
Turfa
Uretren
Urocaudal
ATC C03DB02
CID 5546
CAS 000396010
Drugbank ID DB00384
TTD Drug ID DAP000575
SMILES NC1=NC2=C(N=C(C3=CC=CC=C3)C(N)=N2)C(N)=N1
Formula C12H11N7
Molweight 253.263
Atoms 19
LogP 2.577
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 7
CYP interactions
NameRelationsReferences
1A2Substrate Inhibitor 16035375
16035375
Transporter
AC-No.NameReferences
C7EWH7Sodium transporter6320883
O15244Solute carrier family 22 member 216394027
O15245Solute carrier family 22 member 111708789
P19634SLC9A1 16831598
Q9UBY0Sodium/hydrogen exchanger 2 8512555
Extrarenal fraction 0.7
Elimination half-life 4h