Compound - Results

Clonidine

Java required.


Information Structure
Name Clonidine
Synonyms
1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-
2,6-Dichloro-N-2-imidazolidinylidenebenzenamine
2-((2,6-Dichlorophenyl)imino)imidazolidine
2-(2,6-Dichloroanilino)-1,3-diazacyclopentene-(2)
2-(2,6-Dichloroanilino)-2-imidazoline
2-(2,6-Dichlorophenylamino)-2-imidazoline
734571A
Adesipress
Benzenamine, 2,6-dichloro-N-2-imidazolidinylidene-
Catapres-TTS
Catarpres
Catarpresan
CCRIS 7787
Chlornidinum
Clonidin
Clonidina
Clonidine
Clonidinum
Duraclon
EINECS 224-119-4
HSDB 3040
M-5041T
ST-155-BS
ATC C02AC01
N02CX02
S01EA04
CID 2803
CAS 004205907
Drugbank ID DB00575
TTD Drug ID DAP000231
SMILES ClC1=CC=CC(Cl)=C1NC2=NCCN2
Formula C9H9Cl2N3
Molweight 230.094
Atoms 14
LogP 2.2019
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 3
CYP interactions
NameRelationsReferences
19AInducer 1507273
Phase2 interactions
NameReferences
NAT 2568481,
2878334
Transporter
AC-No.NameReferences
P52569CAT2 18809522
Extrarenal fraction 0.4
Elimination half-life 15h
Guanfacine

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Information Structure
Name Guanfacine
Synonyms
EINECS 249-442-8
Guanfacina
Guanfacine
Guanfacinum
ATC C02AC02
CID 3519
CAS 029110472
Drugbank ID DB01018
TTD Drug ID DAP000900
SMILES NC(=N)NC(=O)CC1=C(Cl)C=CC=C1Cl
Formula C9H9Cl2N3O
Molweight 246.093
Atoms 15
LogP 2.7365
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 4
Transporter
AC-No.NameReferences
P52569CAT2 18809522
Tolonidine

Java required.


Information Structure
Name Tolonidine
Synonyms
Tolonidina
Tolonidine
Tolonidinum
ATC C02AC04
CID 72138
CAS 004201223
SMILES CC1=CC=C(NC2=NCCN2)C(Cl)=C1
Formula C10H12ClN3
Molweight 209.675
Atoms 14
LogP 1.8569
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 3
Transporter
AC-No.NameReferences
P52569CAT2 18809522
Moxonidine

Java required.


Information Structure
Name Moxonidine
Synonyms
4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine
BDF 5895
BE 5895
LY 326869
Moxonidina
Moxonidine
Moxonidinum
Norcynt
Nucynt
ATC C02AC05
CID 4810
CAS 075438572
SMILES COC1=C(N=C2NCCN2)C(Cl)=NC(C)=N1
Formula C9H12ClN5O
Molweight 241.677
Atoms 16
LogP 0.6555
Rotatable Bonds 3
H-Bond Donors 0
H-Bond Acceptors 6
Transporter
AC-No.NameReferences
P52569CAT2 18809522
Extrarenal fraction 0.4
Elimination half-life 2h
Rilmenidine

Java required.


Information Structure
Name Rilmenidine
Synonyms
2-((Dicyclopropylmethyl)imino)oxazolidine
2-(Dicyclopropylmethylamino)-2-oxazoline
2-Oxazolamine, 4,5-dihydro-N-(dicyclopropylmethyl)-
BRN 1211287
EINECS 259-021-0
Methylamine, 1,1-dicyclopropyl-N-(2-oxazolinyl)-
Rilmenidene
Rilmenidia
Rilmenidine
Rilmenidinum
S3341
ATC C02AC06
CID 68712
CAS 054187041
SMILES C1CN=C(NC([C@H]2CC2)[C@H]3CC3)O1
Formula C10H16N2O
Molweight 180.247
Atoms 13
LogP 0.9773
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 3
Transporter
AC-No.NameReferences
P52569CAT2 18809522