Compound - Results

Phentermine

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Information Structure
Name Phentermine
Synonyms
1,1-Dimethyl-2-phenylethylamine
2-Amino-2-methyl-1-phenylpropane
2-Phenyl-tert-butylamine
4-12-00-02820 (Beilstein Handbook Reference)
alpha,alpha-Dimethyl-beta-phenylethylamine
alpha,alpha-Dimethylbenzeneethanamine
alpha,alpha-Dimethylphenethylamine
alpha-Benzylisopropylamine
BRN 0970319
Duromine
EINECS 204-522-1
Ethanamine, 1,1-dimethyl-2-phenyl-
Fastin
Fentermina
HSDB 3158
Ionamin
Linyl
Lipopill
Lonamin
Mirapront
Normephentermine
Obermine
Omnibex
Phentermine
Phenterminum
Phentrol
Phentrol 2
Phentrol 3
Phentrol 4
Phenyl-tert-butylamine
Phenyl-tertiary-butylamine
RCRA Waste Number P046
Wilpo
ATC A08AA01
CID 4771
CAS 000122098
Drugbank ID DB00191
TTD Drug ID DAP000719
SMILES CC(C)(N)CC1=CC=CC=C1
Formula C10H15N
Molweight 149.233
Atoms 11
LogP 2.6667
Rotatable Bonds 2
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
1A2Inhibitor 9690701
2C9Inhibitor Inducer 9690701
2D6Inhibitor 9690701
Fenfluramine

Java required.


Information Structure
Name Fenfluramine
Synonyms
1-(meta-Trifluoromethyl-phenyl)-2 Ethylaminopropane
2-Ethylamino-1-(3-trifluoromethylphenyl)propane
3-(Trifluoromethyl)-N-ethyl-alpha-methylphenethylamine
Benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-
BRN 4783711
EINECS 207-276-3
Fenfluramina
Fenfluramine
Fenfluraminum
HSDB 3080
N-Ethyl-alpha-methyl-3-(trifluoromethyl)benzeneethanamine
N-Ethyl-alpha-methyl-3-trifluoromethylphenethylamine
N-Ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine
Phenethylamine, N-ethyl-alpha-methyl-m-(trifluoromethyl)-
S 768
ATC A08AA02
CID 3337
CAS 000458242
TTD Drug ID DAP001478
SMILES CCN[C@@H](C)CC1=CC(=CC=C1)C(F)(F)F
CYP interactions
NameRelationsReferences
2D6Inhibitor 9690701
Extrarenal fraction 0.6
Elimination half-life 19h
Amfepramone

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Information Structure
Name Amfepramone
Synonyms
1-Phenyl-2-diethylamino-1-propanone
1-Propanone, 2-(diethylamino)-1-phenyl-
2-(Diethylamino)-1-phenyl-1-propanone
2-(Diethylamino)propiophenone
4-14-00-00144 (Beilstein Handbook Reference)
Adiposon
alpha-Benzoyltriethylamine
alpha-Diethylaminopropiophenone
Amfepramon
Amfepramone
Amfepramonum
Amphepramon
Amphepramone
Anfepramona
Anorex
BRN 2804400
Cegramine
Danylen
Derfon
Diethylpropion
Diethylpropione
Dobesin
EINECS 202-019-1
Fenyl-(1-diethylaminoethyl)keton
Frekentine
HSDB 3059
Magrene
Neobes
Nopropiophenone
Obesitex
Propiophenone, 2-(diethylamino)-
Silutin
Tepanil
Tylinal
UR 1423
ATC A08AA03
CID 7029
CAS 000090846
Drugbank ID DB00937
TTD Drug ID DCL000974
SMILES CCN(CC)[C@@H](C)C(=O)C1=CC=CC=C1
Formula C13H19NO
Molweight 205.296
Atoms 15
LogP 2.5996
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 2
Dexfenfluramine

Java required.


Information Structure
Name Dexfenfluramine
Synonyms
(+)-Fenfluramine
(S)-Fenfluramine
Adifax
d-Fenfluramine
d-N-Ethyl-alpha-methyl-m-trifluoromethylphenethylamine
Dexafenfluramine
Dexfenfluramina
Dexfenfluramine
Dexfenfluraminum
Dextrofenfluramine
Redux
ATC A08AA04
CID 3337
CAS 003239449
TTD Drug ID DAP001478
SMILES CCN[C@@H](C)CC1=CC(=CC=C1)C(F)(F)F
Formula C12H16F3N
Molweight 231.257
Atoms 16
LogP 3.6368
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 4
CYP interactions
NameRelationsReferences
1A2Substrate Inhibitor 9825834
9825834
9690701
2A6Inhibitor 9825834
2C9Inhibitor 9825834
9690701
2C19Inhibitor 9825834
2D6Substrate Inhibitor 9825834
8730977
8730977
9825834
9690701
9825834
9825834
2E1Inhibitor 9690701
Extrarenal fraction 0.9
Elimination half-life 18h
Mazindol

Java required.


Information Structure
Name Mazindol
Synonyms
3H-Imidazo(2,1-a)isoindol-5-ol, 2,5-dihydro-5-(4-chlorophenyl)-
3H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,5-dihydro-
3H-Imidazo(2,1-a)isoindol-5-ol, 5-(p-chlorophenyl)-2,5-dihydro-
5-(4-Chlorophenyl)-2,3-dihydro-5-hydroxy-5H-imidazo(2,1-a)isoindole
5-(p-Chlorophenyl)-2,5-dihydro-3H-imidazo(2,1-a)isoindol-5-ol
5-24-04-00402 (Beilstein Handbook Reference)
5-p-Chlorophenyl-2,3-dihydro-5H-imidazo(2,1-a)isoindol-5-ol
5H-Imidazo(2,1-a)isoindol-5-ol, 5-(4-chlorophenyl)-2,3-dihydro
AN 448
BRN 0546547
CCRIS 3152
Dimagrir
EINECS 244-857-0
HSDB 3112
Magrilon
Mazanor
Mazildene
Mazindol
Mazindolum
SA 42-548
SAH 42548
Sanorex
Teronac
ATC A08AA05
CID 4020
CAS 022232719
Drugbank ID DB00579
TTD Drug ID DAP000722
SMILES O[C@@]1(N2CCN=C2C3=C1C=CC=C3)C4=CC=C(Cl)C=C4
Formula C16H13ClN2O
Molweight 284.74
Atoms 20
LogP 1.9827
Rotatable Bonds 1
H-Bond Donors 0
H-Bond Acceptors 2
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 312213053
Q01959SLC6A312358732
Etilamfetamine

Java required.


Information Structure
Name Etilamfetamine
Synonyms
1-Phenyl-2-aethylamino-propan
1-Phenyl-2-ethylaminopropane
3-12-00-02668 (Beilstein Handbook Reference)
alpha-Phenyl-beta-ethylaminopropane
Apetinil
BRN 2357701
Ethylamphetamine
Etilamfetamina
Etilamfetamine
Etilamfetaminum
Etilanfetamina
N-Ethylamphetamine
ATC A08AA06
CID 9982
CAS 000457874
SMILES CCN[C@@H](C)CC1=CC=CC=C1
Formula C11H17N
Molweight 163.259
Atoms 12
LogP 2.618
Rotatable Bonds 4
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
2D6Substrate 10456690
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 312213053
Q01959SLC6A312358732
Cathine

Java required.


Information Structure
Name Cathine
Synonyms
4-13-00-01874 (Beilstein Handbook Reference)
BRN 2802895
Cathina
Cathine
Cathinum
d-Nor-psi-ephedrine
d-Norpseudoephedrine
EINECS 207-754-1
Katine
Pseudonorephedrine
psi-Norephedrine
threo-1-Phenyl-1-hydroxy-2-aminopropane
threo-2-Amino-1-hydroxy-1-phenylpropane
ATC A08AA07
CID 441457
CAS 000492397
Drugbank ID DB00397
SMILES C[C@@H](N)[C@H](O)C1=CC=CC=C1
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 312213053
Q01959SLC6A312358732
Clobenzorex

Java required.


Information Structure
Name Clobenzorex
Synonyms
BRN 2940566
Clobenzorex
Clobenzorexum
Dinintel
EINECS 236-434-4
SD 271-12
ATC A08AA08
CID 71675
CAS 013364324
SMILES C[C@H](CC1=CC=CC=C1)NCC2=C(Cl)C=CC=C2
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 312213053
Q01959SLC6A312358732
Mefenorex

Java required.


Information Structure
Name Mefenorex
Synonyms
BRN 2833093
EINECS 241-279-0
Mefenorex
Mefenorexum
N-(3-Chloropropyl)-alpha-methylbenzeneethanamine
Rondimen
ATC A08AA09
CID 21777
CAS 017243571
SMILES C[C@@H](CC1=CC=CC=C1)NCCCCl
Formula C12H18ClN
Molweight 211.731
Atoms 14
LogP 3.227
Rotatable Bonds 6
H-Bond Donors 0
H-Bond Acceptors 1
Transporter
AC-No.NameReferences
A2RUN4Solute carrier family 6 (Neurotransmitter transporter, dopamine), member 312213053
Q01959SLC6A312358732
Sibutramine

Java required.


Information Structure
Name Sibutramine
Synonyms
Medaria
Reductil
Sibutramina
Sibutramine
Sibutraminum
ATC A08AA10
CID 5210
CAS 106650560
Drugbank ID DB01105
TTD Drug ID DAP000176
SMILES CC(C)C[C@@H](N(C)C)[C@]1(CCC1)C2=CC=C(Cl)C=C2
Formula C17H26ClN
Molweight 279.848
Atoms 19
LogP 4.738
Rotatable Bonds 5
H-Bond Donors 0
H-Bond Acceptors 1
CYP interactions
NameRelationsReferences
3A4Substrate 10492502
Transporter
AC-No.NameReferences
P23975SLC6A517284621