Target Details

Name:	Peptidyl-prolyl cis-trans isomerase A
Uniprot name:	PPIA_HUMAN
Accession Numbers:	P05092 P62937 Q3KQW3 Q6IBU5 Q96IX3 Q9BRU4 Q9BTY9 Q9UC61
EC-Number:	5.2.1.8
Organism:	Homo sapiens Human
PDB IDs:	1AK4 1AWQ 1AWR 1AWS 1AWT 1AWU 1AWV 1BCK 1CWA 1CWB 1CWC 1CWF 1CWH 1CWI 1CWJ 1CWK 1CWL 1CWM 1CWO 1FGL 1M63 1M9C 1M9D 1M9E 1M9F 1M9X 1M9Y 1MF8 1MIK 1NMK 1OCA 1RMH 1VBS 1VBT 1W8L 1W8M 1W8V 1YND 1ZKF 2ALF 2CPL 2CYH 2RMA 2RMB 3CYH 3CYS 4CYH 5CYH
KEGG Pathways:	-
Drugs:	Name PubChem ID Source References Interaction ()-oxazepam hemisuccinate sodium salt 44358264 BindingDB - show ()-oxazepam hemisuccinate sodium salt 44358491 BindingDB - show ()-oxazepam hemisuccinate sodium salt 44358265 BindingDB - show ()-oxazepam hemisuccinate sodium salt 44358332 BindingDB - show ()-oxazepam hemisuccinate sodium salt 44358492 BindingDB - show ()-oxazepam hemisuccinate sodium salt 44358342 BindingDB - show ()-oxazepam hemisuccinate sodium salt 49863381 BindingDB - show ()-oxazepam hemisuccinate sodium salt 49863382 BindingDB - show ()-oxazepam hemisuccinate sodium salt 49863383 BindingDB - show ()-oxazepam hemisuccinate sodium salt 52946681 BindingDB - show ()-oxazepam hemisuccinate sodium salt 52940634 BindingDB - show ()-oxazepam hemisuccinate sodium salt 52945243 BindingDB - show ()-oxazepam hemisuccinate sodium salt 52946682 BindingDB - show 2-yl)benzenesulfonamide 44582823 BindingDB - show AC1L9G81 444384 BindingDB - show AC1LAX4R 497077 BindingDB - show AC1LRDNV 1367020 BindingDB - show AC1MUB56 3663276 BindingDB - show AC1N4HBA 4128827 BindingDB - show AC1N8XHV 4401642 BindingDB - show AC1NN3AK 5020377 BindingDB - show AC1NONRS 5116189 BindingDB - show AI-204/31695004 11660364 BindingDB - show AIDS085126 6475368 BindingDB - show Bio-0872 16404350 BindingDB - show Carboxypyrrolidine 145742 DrugBank - show CHEBI:328305 9855081 BindingDB - show CHEBI:328305 11643846 BindingDB - show CHEMBL1269583 52941831 BindingDB - show CHEMBL1269584 52947912 BindingDB - show CHEMBL1269585 52946683 BindingDB - show CHEMBL1269586 52945473 BindingDB - show CHEMBL1269587 52947949 BindingDB - show CHEMBL1269589 52940669 BindingDB - show CHEMBL1269590 52940670 BindingDB - show CHEMBL1269591 52940671 BindingDB - show CHEMBL1269592 24814873 BindingDB - show CHEMBL1269593 52945496 BindingDB - show CHEMBL1269594 52947950 BindingDB - show CHEMBL1269595 52941859 BindingDB - show CHEMBL1269596 50899161 BindingDB - show CHEMBL146970 44366403 BindingDB - show CHEMBL148477 44366303 BindingDB - show CHEMBL148546 44366208 BindingDB - show CHEMBL148657 44366390 BindingDB - show CHEMBL149224 44366350 BindingDB - show CHEMBL150749 44366040 BindingDB - show CHEMBL151360 44366261 BindingDB - show CHEMBL151381 44366450 BindingDB - show CHEMBL151384 44366232 BindingDB - show CHEMBL151385 44366233 BindingDB - show CHEMBL151816 44366260 BindingDB - show CHEMBL198293 11717355 BindingDB - show CHEMBL199550 11675245 BindingDB - show CHEMBL201025 11531251 BindingDB - show CHEMBL201113 11710570 BindingDB - show CHEMBL201394 11639129 BindingDB - show CHEMBL201395 11631957 BindingDB - show CHEMBL201450 11638938 BindingDB - show CHEMBL201645 11617502 BindingDB - show CHEMBL201664 11588606 BindingDB - show CHEMBL201718 11574097 BindingDB - show CHEMBL203100 44406917 BindingDB - show CHEMBL203142 11703833 BindingDB - show CHEMBL203194 11516665 BindingDB - show CHEMBL263062 44366453 BindingDB - show CHEMBL264229 13037937 BindingDB - show CHEMBL266308 44358399 BindingDB - show CHEMBL266503 44358277 BindingDB - show CHEMBL267710 44347614 BindingDB - show CHEMBL274113 44358331 BindingDB - show CHEMBL276363 44294709 BindingDB - show CHEMBL295937 44294875 BindingDB - show CHEMBL295942 44295258 BindingDB - show CHEMBL296587 44294708 BindingDB - show CHEMBL297131 44295050 BindingDB - show CHEMBL299145 44295067 BindingDB - show CHEMBL299202 44295153 BindingDB - show CHEMBL299372 44295134 BindingDB - show CHEMBL300089 44295136 BindingDB - show CHEMBL300523 44294838 BindingDB - show CHEMBL313327 10051106 BindingDB - show CHEMBL314456 10023554 BindingDB - show CHEMBL315033 11730110 BindingDB - show CHEMBL329797 44321275 BindingDB - show CHEMBL341860 44365970 BindingDB - show CHEMBL356248 44366391 BindingDB - show CHEMBL357384 44366144 BindingDB - show CHEMBL358023 44366404 BindingDB - show CHEMBL358478 44366351 BindingDB - show CHEMBL358925 44366405 BindingDB - show CHEMBL371213 11567780 BindingDB - show CHEMBL373254 11632684 BindingDB - show CHEMBL382465 11718015 BindingDB - show CHEMBL382567 11559871 BindingDB - show CHEMBL384058 44393427 BindingDB - show CHEMBL384516 44358391 BindingDB - show CHEMBL384718 44393512 BindingDB - show CHEMBL384726 44341483 BindingDB - show CHEMBL404789 44347622 BindingDB - show CHEMBL405301 44358392 BindingDB - show CHEMBL407342 44341642 BindingDB - show CHEMBL407456 44393513 BindingDB - show CHEMBL407798 44358330 BindingDB - show CHEMBL408273 44358251 BindingDB - show CHEMBL409139 44393426 BindingDB - show CHEMBL409283 44358333 BindingDB - show CHEMBL409911 44358288 BindingDB - show CHEMBL413867 44393514 BindingDB - show CHEMBL415597 44341507 BindingDB - show CHEMBL424038 44295020 BindingDB - show CHEMBL426517 44358250 BindingDB - show CHEMBL433082 44294814 BindingDB - show CHEMBL433738 44366452 BindingDB - show CHEMBL434694 44366209 BindingDB - show CHEMBL438817 44393425 BindingDB - show CHEMBL439455 44358490 BindingDB - show CHEMBL443992 25098030 BindingDB - show CHEMBL445240 25098029 BindingDB - show CHEMBL482839 44582699 BindingDB - show CHEMBL482840 44582700 BindingDB - show CHEMBL48778 44294978 BindingDB - show CHEMBL48822 44294940 BindingDB - show CHEMBL48825 44295056 BindingDB - show CHEMBL48875 44294971 BindingDB - show CHEMBL489001 44582756 BindingDB - show CHEMBL489021 44582780 BindingDB - show CHEMBL489042 44582824 BindingDB - show CHEMBL489612 25097748 BindingDB - show CHEMBL489614 25098028 BindingDB - show CHEMBL490247 44582805 BindingDB - show CHEMBL490840 20414882 BindingDB - show CHEMBL490848 44582757 BindingDB - show CHEMBL492070 25098032 BindingDB - show CHEMBL49783 44294512 BindingDB - show CHEMBL50531 44295152 BindingDB - show CHEMBL50853 44294510 BindingDB - show CHEMBL50854 44294511 BindingDB - show CHEMBL50991 44294787 BindingDB - show CHEMBL51248 44294970 BindingDB - show CHEMBL51732 44295066 BindingDB - show CHEMBL518980 44582698 BindingDB - show CHEMBL52165 44294584 BindingDB - show CHEMBL521943 42630203 BindingDB - show CHEMBL522094 44582804 BindingDB - show CHEMBL525897 44249040 BindingDB - show CHEMBL540193 44366451 BindingDB - show CHEMBL540479 44249303 BindingDB - show CHEMBL549627 44248910 BindingDB - show CHEMBL549755 44249309 BindingDB - show CHEMBL550098 44249304 BindingDB - show CHEMBL551508 44248913 BindingDB - show CHEMBL551796 45269870 BindingDB - show CHEMBL552181 44249307 BindingDB - show CHEMBL552255 44249306 BindingDB - show CHEMBL556893 44249310 BindingDB - show CHEMBL557628 44248912 BindingDB - show CHEMBL558302 44249174 BindingDB - show CHEMBL559525 44249042 BindingDB - show CHEMBL559858 44249305 BindingDB - show CHEMBL560115 44249173 BindingDB - show CHEMBL560173 44248911 BindingDB - show CHEMBL560850 44249039 BindingDB - show CHEMBL560851 44249041 BindingDB - show CHEMBL564391 44248914 BindingDB - show CHEMBL564539 44249170 BindingDB - show CHEMBL564647 44249414 BindingDB - show CHEMBL564826 44249044 BindingDB - show CHEMBL569840 44249415 BindingDB - show CHEMBL86442 11046232 BindingDB - show CHEMBL86465 15293457 BindingDB - show CHEMBL88028 10993110 BindingDB - show CHEMBL89881 11091428 BindingDB - show CID 10805065 10591196 BindingDB - show CID 11833443 10891863 BindingDB - show CID 11833443 11833443 BindingDB - show cyclosporin A 5284373 BindingDB - show cyclosporin A 5280754 BindingDB - show CYCLOSPORINE 6435893 DrugBank - show methoxyphenyl)benzenesulfonamide 19678899 BindingDB - show methyl-L-valyl] 6476061 BindingDB - show nitrophenyl)thiourea (D2) 20415061 BindingDB - show Oprea1_029075 25047343 BindingDB - show Oprea1_148017 25046022 BindingDB - show Oprea1_179475 25044910 BindingDB - show Oprea1_450954 13578706 BindingDB - show Oprea1_643359 13578707 BindingDB - show SCY-635 49863459 BindingDB - show SCY-635 6479267 BindingDB - show yl)benzenesulfonamide 13422114 BindingDB - show ZINC00171159 2823177 BindingDB - show ZINC00171166 2823184 BindingDB - show ZINC00171175 2823189 BindingDB - show enlarge table
Synonyms:	Cyclophilin A Cyclosporin A-binding protein Peptidyl-prolyl cis-trans isomerase A PPIase A Rotamase A enlarge table
Similar targets:	Uniprot name % Sequence similarity % Sequence identity PPIA_PAPAN 100 100 PPIF_HUMAN 67.1 59.9 PPIH_HUMAN 65.7 51.1 PPIB_HUMAN 57.6 49.3 CYP5_CAEEL 56.4 46.6 PPIC_HUMAN 52.3 44.4 SAT2_HUMAN 38.7 20.9 MYG_PIG 33.7 21.6 RISB_AQUAE 33.5 17.3 CYC2_RHOVI 33.1 21.1 CANB1_HUMAN 32.5 19.8 SODC_BOVIN 32.4 21.8 SAV_STRAV 32.2 19.7 Q9X9L0_THETH 32.2 18.8 AZRB_BACOY 31.9 18.6 FUCL_ANGAN 31.6 16.6 ICYA_MANSE 31.5 19.6 MACM_STRMA 31.5 20.7 PHI_METJA 31 18.7 ARF2_YEAST 30.8 17.5 RL13_DEIRA 30.7 16.3 MYG_HORSE 30.6 22.8 ACPS_BACSU 30.6 17.3 CBIT_METTH 30.5 18.3 NIKR_SHIFL 30.5 17.5 SODC_SCHMA 30.4 21.5 Y1796_ARCFU 30.2 17.5 Q9RW27_DEIRA 30.2 18 GLB1_SCAIN 30.2 17.7 GSTP_ONCVO 30 16 enlarge table
Protein-Protein Interactions:	Uniprot name Source UNG_HUMAN PMID 16049941 UCHL1_HUMAN 2 PMIDs UCHL1_HUMAN 3 PMIDs TYY1_HUMAN 4 PMIDs TBB5_HUMAN 5 PMIDs TBB5_HUMAN 6 PMIDs STXB1_HUMAN 7 PMIDs SPTA2_HUMAN 8 PMIDs SPT5H_HUMAN 9 PMIDs S10A8_HUMAN 10 PMIDs Q71V99_HUMAN 11 PMIDs PTPRN_HUMAN 12 PMIDs PSIP1_HUMAN 13 PMIDs PRS23_HUMAN 14 PMIDs PRR13_HUMAN 15 PMIDs PRLR_HUMAN 16 PMIDs PPIA_HUMAN 17 PMIDs PP2BA_HUMAN 18 PMIDs PGAM1_HUMAN 19 PMIDs PGAM1_HUMAN 20 PMIDs NSF_HUMAN 21 PMIDs NSF_HUMAN 22 PMIDs NFL_HUMAN 23 PMIDs NFL_HUMAN 24 PMIDs MBP_HUMAN 25 PMIDs M3K5_HUMAN 26 PMIDs M3K5_HUMAN 27 PMIDs JAK2_HUMAN 28 PMIDs ITK_HUMAN 29 PMIDs HSP7C_HUMAN 30 PMIDs HSP7C_HUMAN 31 PMIDs HS90A_HUMAN 32 PMIDs HS90A_HUMAN 33 PMIDs HMGA1_HUMAN 34 PMIDs GRB2_HUMAN 35 PMIDs GFAP_HUMAN 36 PMIDs GFAP_HUMAN 37 PMIDs DYN1_HUMAN 38 PMIDs DYN1_HUMAN 39 PMIDs DYH1_HUMAN 40 PMIDs CXCR4_HUMAN 41 PMIDs CRYAB_HUMAN 42 PMIDs CRYAB_HUMAN 43 PMIDs CD99_HUMAN 44 PMIDs CD4_HUMAN 45 PMIDs CCR5_HUMAN 46 PMIDs CANB1_HUMAN 47 PMIDs BAF_HUMAN 48 PMIDs APBB1_HUMAN 49 PMIDs ACTB_HUMAN 50 PMIDs ACTB_HUMAN 51 PMIDs ABC3G_HUMAN 52 PMIDs A4_HUMAN 53 PMIDs A4_HUMAN 54 PMIDs A4_HUMAN 55 PMIDs 1433Z_HUMAN 56 PMIDs 1433Z_HUMAN 57 PMIDs 1433Z_HUMAN 58 PMIDs enlarge table

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