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Target Details

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Name:Phenylethanolamine N-methyltransferase
Uniprot name:PNMT_HUMAN
Accession Numbers:P11086
EC-Number:2.1.1.28
Organism:Homo sapiens
Human
PDB IDs:1HNN 1N7I 1N7J 1YZ3 2AN3 2AN4 2AN5 2G70 2G71 2G72 2G8N 2OBF 2ONY 2ONZ 2OPB 3HCA 3HCB 3HCC 3HCD 3HCE 3HCF
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(3S)-3-methyl-7-nitro-1,2,3,4-tetrahydroisoquinoline10487987BindingDB-show
(3S)-3-methyl-7-nitro-1,2,3,4-tetrahydroisoquinoline10607760BindingDB-show
1,2,3,4-Tetrahydroisoquinoline-7-sulfonamide5226BindingDB-show
1,2,3,4-Tetrahydroisoquinoline-7-sulfonamide5226DrugBank-show
1-(2,3-dichlorophenyl)ethanamine1215BindingDB-show
1-Phenylethanamine7408BindingDB-show
2,3-Dichlorobenzylamine587625BindingDB-show
2-Aminobenzonorbornene93889BindingDB-show
2-THIOPHENEMETHANAMINE34005BindingDB-show
3,4-Dichloroamphetamine17535BindingDB-show
3,4-Dichlorophenethylamine217958BindingDB-show
3-(fluoromethyl)-1,2,3,4-tetrahydroisoquinoline10654599BindingDB-show
3-(fluoromethyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide11460195BindingDB-show
3-THIENYLMETHYLAMINE2776381BindingDB-show
4,5,6,7-Tetrahydrothieno(3,2-c)pyridine3085076BindingDB-show
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline123920BindingDB-show
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline123920PROMISCUOUSPMID 7252985show
7-bromo-1,2,3,4-tetrahydroisoquinoline10729255BindingDB-show
7-bromo-3-(fluoromethyl)-1,2,3,4-tetrahydroisoquinoline10514405BindingDB-show
7-Cyano-1,2,3,4-tetrahydroisoquinoline10176243BindingDB-show
7-Nitro-1,2,3,4-tetrahydro-isoquinoline6424833BindingDB-show
7-sulfonamide-THIQ 1210399576BindingDB-show
7-sulfonamide-THIQ 1310263774BindingDB-show
7-sulfonamide-THIQ 1410089519BindingDB-show
7-sulfonamide-THIQ 1511349774BindingDB-show
7-sulfonamide-THIQ 1610019263BindingDB-show
7-sulfonamide-THIQ 1711313333BindingDB-show
7-sulfonamide-THIQ 1811394776BindingDB-show
7-sulfonamide-THIQ 1910634951BindingDB-show
7-sulfonamide-THIQ 2011196556BindingDB-show
7-sulfonamide-THIQ 2110108068BindingDB-show
7-sulfonamide-THIQ 2211244672BindingDB-show
7-sulfonyl-THIQ 1010588353BindingDB-show
7-sulfonyl-THIQ 1110736630BindingDB-show
7-sulfonyl-THIQ 2316082606BindingDB-show
7-sulfonyl-THIQ 2416082608BindingDB-show
7-sulfonyl-THIQ 2516082610BindingDB-show
7-sulfonyl-THIQ 2616082612BindingDB-show
7-sulfonyl-THIQ 2716082614BindingDB-show
7-sulfonyl-THIQ 2816082616BindingDB-show
7-sulfonyl-THIQ 2916082618BindingDB-show
7-sulfonyl-THIQ 3016082631BindingDB-show
7-sulfonyl-THIQ 3110610245BindingDB-show
7-sulfonyl-THIQ 823336575BindingDB-show
7-sulfonyl-THIQ 910733711BindingDB-show
8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine hydrochloride121938BindingDB-show
8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine hydrochloride121938DrugBank-show
9-Atfmb135924BindingDB-show
Acylcarnitine34756BindingDB-show
BRN 280667030514BindingDB-show
CHEBI:64855144377668BindingDB-show
CHEBI:64855544377706BindingDB-show
CHEBI:64856944377973BindingDB-show
CHEBI:64857444377666BindingDB-show
CHEBI:64857944377958BindingDB-show
CHEBI:65087144286330BindingDB-show
CHEBI:65247744377667BindingDB-show
CHEBI:65256844377669BindingDB-show
CHEMBL11203844340624BindingDB-show
CHEMBL11235110332138BindingDB-show
CHEMBL11235744340588BindingDB-show
CHEMBL11296410401405BindingDB-show
CHEMBL13595710618144BindingDB-show
CHEMBL13595910784360BindingDB-show
CHEMBL14618812595071BindingDB-show
CHEMBL14902220027470BindingDB-show
CHEMBL14902312595069BindingDB-show
CHEMBL14953512595085BindingDB-show
CHEMBL14981612595087BindingDB-show
CHEMBL16513244377694BindingDB-show
CHEMBL16525244377697BindingDB-show
CHEMBL16542544377699BindingDB-show
CHEMBL16542644377698BindingDB-show
CHEMBL17427411772571BindingDB-show
CHEMBL17509411312887BindingDB-show
CHEMBL17551911325218BindingDB-show
CHEMBL17552711208994BindingDB-show
CHEMBL17593511209657BindingDB-show
CHEMBL17706211232465BindingDB-show
CHEMBL17710111349402BindingDB-show
CHEMBL17793611325652BindingDB-show
CHEMBL17929811438678BindingDB-show
CHEMBL18237611608298BindingDB-show
CHEMBL18277444392609BindingDB-show
CHEMBL18297044392584BindingDB-show
CHEMBL18406911257061BindingDB-show
CHEMBL18429611222628BindingDB-show
CHEMBL18447111439655BindingDB-show
CHEMBL18462711222591BindingDB-show
CHEMBL18523344392613BindingDB-show
CHEMBL18599111450547BindingDB-show
CHEMBL18599210425899BindingDB-show
CHEMBL18636111303206BindingDB-show
CHEMBL18689511739550BindingDB-show
CHEMBL18811711235364BindingDB-show
CHEMBL18871611326749BindingDB-show
CHEMBL18878211348278BindingDB-show
CHEMBL18965911772989BindingDB-show
CHEMBL18966411349331BindingDB-show
CHEMBL19677044405406BindingDB-show
CHEMBL19697044405404BindingDB-show
CHEMBL19701944405405BindingDB-show
CHEMBL19738044405400BindingDB-show
CHEMBL19873344405513BindingDB-show
CHEMBL19889611680583BindingDB-show
CHEMBL19900844405471BindingDB-show
CHEMBL20037544405495BindingDB-show
CHEMBL20056044405494BindingDB-show
CHEMBL20056344405499BindingDB-show
CHEMBL20091044405493BindingDB-show
CHEMBL20689210377457BindingDB-show
CHEMBL20751611501635BindingDB-show
CHEMBL20756111645402BindingDB-show
CHEMBL20756211546250BindingDB-show
CHEMBL20782511566070BindingDB-show
CHEMBL20785511558328BindingDB-show
CHEMBL20791711514913BindingDB-show
CHEMBL20804011522432BindingDB-show
CHEMBL20812611632695BindingDB-show
CHEMBL20817311566312BindingDB-show
CHEMBL20818011597095BindingDB-show
CHEMBL20823311501582BindingDB-show
CHEMBL24317644428302BindingDB-show
CHEMBL24383444428299BindingDB-show
CHEMBL24383544428301BindingDB-show
CHEMBL24383616216219BindingDB-show
CHEMBL25260544447172BindingDB-show
CHEMBL25260644447174BindingDB-show
CHEMBL25280644447169BindingDB-show
CHEMBL25280844447176BindingDB-show
CHEMBL25301020065702BindingDB-show
CHEMBL25321844447170BindingDB-show
CHEMBL25321944447171BindingDB-show
CHEMBL25385944447165BindingDB-show
CHEMBL25386044447167BindingDB-show
CHEMBL26781911639665BindingDB-show
CHEMBL27559510565477BindingDB-show
CHEMBL28736010632080BindingDB-show
CHEMBL28852544287137BindingDB-show
CHEMBL29001020204011BindingDB-show
CHEMBL34232244363399BindingDB-show
CHEMBL35057144377693BindingDB-show
CHEMBL35137844377597BindingDB-show
CHEMBL35139421393811BindingDB-show
CHEMBL35558111337570BindingDB-show
CHEMBL35643912595086BindingDB-show
CHEMBL35920544363251BindingDB-show
CHEMBL3598210263132BindingDB-show
CHEMBL36019911245059BindingDB-show
CHEMBL36174944392595BindingDB-show
CHEMBL36348411360541BindingDB-show
CHEMBL36608511484843BindingDB-show
CHEMBL3690910711778BindingDB-show
CHEMBL37079444405506BindingDB-show
CHEMBL37108444405407BindingDB-show
CHEMBL37189844405440BindingDB-show
CHEMBL37766911531025BindingDB-show
CHEMBL38031011601371BindingDB-show
CHEMBL38129711500379BindingDB-show
CHEMBL38159611582118BindingDB-show
CHEMBL39045344428303BindingDB-show
CHEMBL3912522018495BindingDB-show
CHEMBL39847544447166BindingDB-show
CHEMBL39867844447164BindingDB-show
CHEMBL39917818377398BindingDB-show
CHEMBL39917918377285BindingDB-show
CHEMBL39986444447180BindingDB-show
CHEMBL40051544447173BindingDB-show
CHEMBL4008110750185BindingDB-show
CHEMBL4107921687108BindingDB-show
CHEMBL41331144428300BindingDB-show
CHEMBL4148744287195BindingDB-show
CHEMBL4168944287234BindingDB-show
CHEMBL42552210471609BindingDB-show
CHEMBL42612811514463BindingDB-show
CHEMBL42644211349134BindingDB-show
CHEMBL4302110331921BindingDB-show
CHEMBL4318344286717BindingDB-show
CHEMBL43769944405498BindingDB-show
CHEMBL43986421584293BindingDB-show
CHEMBL44479321539587BindingDB-show
CHEMBL45936644590556BindingDB-show
CHEMBL5944121584368BindingDB-show
CHEMBL5971915407445BindingDB-show
EINECS 222-659-519349BindingDB-show
Exp 56127697BindingDB-show
F2111485425BindingDB-show
Formycinylhomocysteine439155DrugBank-show
m-Chlorobenzylamine77802BindingDB-show
o-Chlorobenzylamine66648BindingDB-show
p-Chloramphetamine3127BindingDB-show
S-adenosylmethionine chloride90473BindingDB-show
Tetrahydroisoquinoline7046BindingDB-show
tetrahydroisoquinoline (THIQ) deriv. 25288606BindingDB-show
tetrahydroisoquinoline (THIQ) deriv. 25288606DrugBank-show
Thiophene-2-ethylamine116521BindingDB-show
TMJ12606920BindingDB-show
[(3R)-7-bromo-1,2,3,4-tetrahydroisoquinolin-3-yl]methanol11776489BindingDB-show
Synonyms:
Noradrenaline N-methyltransferase
Phenylethanolamine N-methyltransferase
PNMTase
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PNMT_RAT89.582.5
NNMT_HUMAN52.935.4
GAMT_HUMAN33.718.5
SPEE_HUMAN32.518.2
GAMT_RAT31.817.9
DCXR_HUMAN31.317.7
ECI1_HUMAN31.320.2
Q99MI5_RAT31.316.3
Q94KL8_PODPE3117.4
Q53Y97_HUMAN30.920.6
Q53FB7_HUMAN30.920.6
TYSY_HUMAN30.920.6
CYC9_DESDA30.918.9
Q9RZ04_DEIRA30.823.1
NMNA1_MOUSE30.717.4
GLYL2_HUMAN30.617.1
BIOD1_ECOLI30.519.2
Q8WYK4_HUMAN30.419.5
DYR_HUMAN30.416.7
O69755_PSEAE30.420.3
P5CR3_HUMAN30.219.3
Q8U3I1_PYRFU30.216
GNMT_MOUSE30.218.8
P72322_RHORU30.118
Q75WK2_THETH29.819.5
HEMK_ECOLI29.820.2
DHSB_HUMAN29.717.3
YMX7_YEAST29.616
MMCD_ECOLI29.517.4
DYR_CHICK29.518.5
Protein-Protein Interactions:
No data available