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Name:Atriopeptidase
Uniprot name:NEP_HUMAN
Accession Numbers:A8K6U6 P08473 Q3MIX4
EC-Number:3.4.24.11
Organism:Homo sapiens
Human
PDB IDs:1DL9 1DMT 1QVD 1R1H 1R1I 1R1J 1Y8J 2QPJ
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
(2-SULFANYL-3-PHENYLPROPANOYL)-PHE-TYR5289470BindingDB-show
1zdp4369380BindingDB-show
2-(4-Morpholinyl)-4H-1-benzopyran-4-one131255BindingDB-show
2-[(2-benzyl-5-methyl-3-sulfanyl-hexanoyl)amino]propanoic Acid10381547BindingDB-show
2-[(FORMYL-HYDROXY-AMINO)-METHYL]-HEXANOIC ACID (1-DIMETHYLCARBAMOYL-2,2-DIMETHYL-PROPYL)-AMIDE159596BindingDB-show
AC1MD03C2828746BindingDB-show
AC1NZV895943893BindingDB-show
AC1OEMTM7059511BindingDB-show
Actinonine443600BindingDB-show
BRN 55448902828749BindingDB-show
Candoxatrilat443380BindingDB-show
Candoxatrilat5362417DrugBank-show
Candoxatrilat443380DrugBank-show
Carphecillin33672SuperTargetPMID 2489237show
Cgs 26303132968BindingDB-show
CHEBI:10669444266433BindingDB-show
CHEBI:10694512877547BindingDB-show
CHEBI:14194144278932BindingDB-show
CHEBI:14198144278951BindingDB-show
CHEBI:14232244279108BindingDB-show
CHEBI:14240044279148BindingDB-show
CHEBI:14241444279155BindingDB-show
CHEBI:14246144279182BindingDB-show
CHEBI:14247544279191BindingDB-show
CHEBI:14248744279198BindingDB-show
CHEBI:14248944279200BindingDB-show
CHEBI:14249244279203BindingDB-show
CHEBI:14250744279214BindingDB-show
CHEBI:14255644279248BindingDB-show
CHEBI:14271344279327BindingDB-show
CHEBI:14273344279336BindingDB-show
CHEBI:14282044279392BindingDB-show
CHEBI:14282144279394BindingDB-show
CHEBI:14282644279399BindingDB-show
CHEBI:14282744279401BindingDB-show
CHEBI:14282844279403BindingDB-show
CHEBI:14284644279414BindingDB-show
CHEBI:14284744279416BindingDB-show
CHEBI:14285144279418BindingDB-show
CHEBI:14285244279420BindingDB-show
CHEBI:14286244279430BindingDB-show
CHEBI:14288944279447BindingDB-show
CHEBI:14293344279477BindingDB-show
CHEBI:14295944279491BindingDB-show
CHEBI:14300244279513BindingDB-show
CHEBI:14300644279517BindingDB-show
CHEBI:14303844279531BindingDB-show
CHEBI:14322244279618BindingDB-show
CHEBI:14322344279620BindingDB-show
CHEBI:14332444279672BindingDB-show
CHEBI:14343744279731BindingDB-show
CHEBI:14345044279738BindingDB-show
CHEBI:14355244279796BindingDB-show
CHEBI:14405244280042BindingDB-show
CHEBI:20546744307768BindingDB-show
CHEBI:28526544340984BindingDB-show
CHEBI:29375144344566BindingDB-show
CHEBI:29378044344579BindingDB-show
CHEBI:29381644344594BindingDB-show
CHEBI:29432544344790BindingDB-show
CHEBI:34707344365324BindingDB-show
CHEBI:34716044365366BindingDB-show
CHEBI:34743744365505BindingDB-show
CHEBI:34747444365525BindingDB-show
CHEBI:34756744365567BindingDB-show
CHEBI:34773244365625BindingDB-show
CHEBI:34806444365794BindingDB-show
CHEBI:34846044365908BindingDB-show
CHEMBL10004444329454BindingDB-show
CHEMBL1025144266525BindingDB-show
CHEMBL1122718980810BindingDB-show
CHEMBL1123621757876BindingDB-show
CHEMBL1129744267283BindingDB-show
CHEMBL1134444267350BindingDB-show
CHEMBL1149523285617BindingDB-show
CHEMBL1153718980806BindingDB-show
CHEMBL1160718980812BindingDB-show
CHEMBL1161618980791BindingDB-show
CHEMBL1162044267301BindingDB-show
CHEMBL1163344267310BindingDB-show
CHEMBL1180644267357BindingDB-show
CHEMBL14657310735551BindingDB-show
CHEMBL1469369863167BindingDB-show
CHEMBL14718510041763BindingDB-show
CHEMBL14752610759255BindingDB-show
CHEMBL14814044364906BindingDB-show
CHEMBL14884010710922BindingDB-show
CHEMBL14936744364917BindingDB-show
CHEMBL14984110759256BindingDB-show
CHEMBL1502229839564BindingDB-show
CHEMBL1604610402181BindingDB-show
CHEMBL16363514054222BindingDB-show
CHEMBL16368244377020BindingDB-show
CHEMBL16462514054186BindingDB-show
CHEMBL1656179888002BindingDB-show
CHEMBL1710713178368BindingDB-show
CHEMBL17185044384300BindingDB-show
CHEMBL17278744384274BindingDB-show
CHEMBL17297844384394BindingDB-show
CHEMBL17328744384017BindingDB-show
CHEMBL17391944384213BindingDB-show
CHEMBL17406644383695BindingDB-show
CHEMBL17511044385237BindingDB-show
CHEMBL17696044385190BindingDB-show
CHEMBL17700044388021BindingDB-show
CHEMBL1907010837017BindingDB-show
CHEMBL1916544272677BindingDB-show
CHEMBL19187910141595BindingDB-show
CHEMBL19244144400838BindingDB-show
CHEMBL19349011192220BindingDB-show
CHEMBL1936244272694BindingDB-show
CHEMBL19465144401169BindingDB-show
CHEMBL1949410695212BindingDB-show
CHEMBL1957344273046BindingDB-show
CHEMBL1962144273070BindingDB-show
CHEMBL1964744273045BindingDB-show
CHEMBL1975510527871BindingDB-show
CHEMBL1981610815454BindingDB-show
CHEMBL1982010828497BindingDB-show
CHEMBL19831644404945BindingDB-show
CHEMBL1984615580540BindingDB-show
CHEMBL19927944404980BindingDB-show
CHEMBL1993544273039BindingDB-show
CHEMBL1993644273040BindingDB-show
CHEMBL1995144272755BindingDB-show
CHEMBL2001044273323BindingDB-show
CHEMBL2005310697176BindingDB-show
CHEMBL2006710837016BindingDB-show
CHEMBL2006844273292BindingDB-show
CHEMBL2012310501165BindingDB-show
CHEMBL2015510528442BindingDB-show
CHEMBL2018244273312BindingDB-show
CHEMBL2019344273114BindingDB-show
CHEMBL2032210744675BindingDB-show
CHEMBL2032644273052BindingDB-show
CHEMBL2034144273054BindingDB-show
CHEMBL2041944273400BindingDB-show
CHEMBL2057444273293BindingDB-show
CHEMBL20888811666940BindingDB-show
CHEMBL20944111704532BindingDB-show
CHEMBL20949311659857BindingDB-show
CHEMBL2096610625854BindingDB-show
CHEMBL2102510813764BindingDB-show
CHEMBL21131411652641BindingDB-show
CHEMBL21138344413815BindingDB-show
CHEMBL21145044413802BindingDB-show
CHEMBL21150010132004BindingDB-show
CHEMBL21152911537626BindingDB-show
CHEMBL21159611652422BindingDB-show
CHEMBL21161011639199BindingDB-show
CHEMBL21165211646207BindingDB-show
CHEMBL21189711595694BindingDB-show
CHEMBL21194311559079BindingDB-show
CHEMBL21200111522221BindingDB-show
CHEMBL21206511688419BindingDB-show
CHEMBL21210511689439BindingDB-show
CHEMBL21222011566540BindingDB-show
CHEMBL21237411561143BindingDB-show
CHEMBL21237711545107BindingDB-show
CHEMBL21240911573732BindingDB-show
CHEMBL2125269969592BindingDB-show
CHEMBL2125729862743BindingDB-show
CHEMBL21277111661185BindingDB-show
CHEMBL21324011682380BindingDB-show
CHEMBL21328111516163BindingDB-show
CHEMBL21340411531417BindingDB-show
CHEMBL21386111566264BindingDB-show
CHEMBL2139449866271BindingDB-show
CHEMBL21396411610321BindingDB-show
CHEMBL21416011544123BindingDB-show
CHEMBL22467044422283BindingDB-show
CHEMBL22508515978653BindingDB-show
CHEMBL2407944275380BindingDB-show
CHEMBL2491044275460BindingDB-show
CHEMBL2491944275911BindingDB-show
CHEMBL2492344275416BindingDB-show
CHEMBL2534144275459BindingDB-show
CHEMBL2543244458298BindingDB-show
CHEMBL26226722732549BindingDB-show
CHEMBL26375644460526BindingDB-show
CHEMBL2670344275775BindingDB-show
CHEMBL26776644267369BindingDB-show
CHEMBL2681444275933BindingDB-show
CHEMBL26847344266469BindingDB-show
CHEMBL26876144266483BindingDB-show
CHEMBL2711044275712BindingDB-show
CHEMBL2711144275713BindingDB-show
CHEMBL2716444275948BindingDB-show
CHEMBL2727344275937BindingDB-show
CHEMBL2732169884141BindingDB-show
CHEMBL27348944266561BindingDB-show
CHEMBL27367244267309BindingDB-show
CHEMBL27372444267348BindingDB-show
CHEMBL27374810107035BindingDB-show
CHEMBL27389844267368BindingDB-show
CHEMBL27414019604194BindingDB-show
CHEMBL27569044267339BindingDB-show
CHEMBL27598044267353BindingDB-show
CHEMBL27600818980765BindingDB-show
CHEMBL27669044266455BindingDB-show
CHEMBL27687244266484BindingDB-show
CHEMBL27770710503259BindingDB-show
CHEMBL2784244275870BindingDB-show
CHEMBL2786844275869BindingDB-show
CHEMBL27875444275546BindingDB-show
CHEMBL2788044275765BindingDB-show
CHEMBL27947510549519BindingDB-show
CHEMBL27996610647563BindingDB-show
CHEMBL28020344272702BindingDB-show
CHEMBL28123744275934BindingDB-show
CHEMBL2815344275871BindingDB-show
CHEMBL28211844275764BindingDB-show
CHEMBL2821544275795BindingDB-show
CHEMBL28215844275916BindingDB-show
CHEMBL28246910690150BindingDB-show
CHEMBL28266410649261BindingDB-show
CHEMBL2827344275461BindingDB-show
CHEMBL28331544273067BindingDB-show
CHEMBL28374144273301BindingDB-show
CHEMBL28481844283535BindingDB-show
CHEMBL2856199806479BindingDB-show
CHEMBL2878969998020BindingDB-show
CHEMBL28797110691661BindingDB-show
CHEMBL28843244285304BindingDB-show
CHEMBL28883710834551BindingDB-show
CHEMBL28913044283412BindingDB-show
CHEMBL28915010622593BindingDB-show
CHEMBL28934844283893BindingDB-show
CHEMBL28959044285120BindingDB-show
CHEMBL28963810764686BindingDB-show
CHEMBL2902569979153BindingDB-show
CHEMBL29030444285096BindingDB-show
CHEMBL29033210694200BindingDB-show
CHEMBL29086810648112BindingDB-show
CHEMBL29253444303134BindingDB-show
CHEMBL29368515518150BindingDB-show
CHEMBL29379444298544BindingDB-show
CHEMBL29510414557663BindingDB-show
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CHEMBL29958814134571BindingDB-show
CHEMBL29994610732349BindingDB-show
CHEMBL3016469982912BindingDB-show
CHEMBL30170344298425BindingDB-show
CHEMBL30238344307701BindingDB-show
CHEMBL30315944307823BindingDB-show
CHEMBL30330222732571BindingDB-show
CHEMBL30389244307822BindingDB-show
CHEMBL30420915518148BindingDB-show
CHEMBL30421822732542BindingDB-show
CHEMBL30462944303111BindingDB-show
CHEMBL30493910236332BindingDB-show
CHEMBL30538844303110BindingDB-show
CHEMBL30929314390770BindingDB-show
CHEMBL31019914390663BindingDB-show
CHEMBL31020044461233BindingDB-show
CHEMBL31060244461085BindingDB-show
CHEMBL31183844314997BindingDB-show
CHEMBL31186944461294BindingDB-show
CHEMBL31246044460818BindingDB-show
CHEMBL31271410383581BindingDB-show
CHEMBL31303614390778BindingDB-show
CHEMBL31328444318793BindingDB-show
CHEMBL31341944325093BindingDB-show
CHEMBL31406314557720BindingDB-show
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CHEMBL31525510447524BindingDB-show
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CHEMBL31617214557750BindingDB-show
CHEMBL31618014557672BindingDB-show
CHEMBL31659544329350BindingDB-show
CHEMBL31819222874515BindingDB-show
CHEMBL31933644329326BindingDB-show
CHEMBL31974422874524BindingDB-show
CHEMBL31983622874530BindingDB-show
CHEMBL32779944325095BindingDB-show
CHEMBL32803010432045BindingDB-show
CHEMBL32846344325081BindingDB-show
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CHEMBL32946444325169BindingDB-show
CHEMBL32947422874522BindingDB-show
CHEMBL32953044325222BindingDB-show
CHEMBL32966644325246BindingDB-show
CHEMBL32989444325303BindingDB-show
CHEMBL33021722874527BindingDB-show
CHEMBL33050744324645BindingDB-show
CHEMBL34209110829618BindingDB-show
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CHEMBL3442744283329BindingDB-show
CHEMBL3454144283330BindingDB-show
CHEMBL34642410494952BindingDB-show
CHEMBL3488444283534BindingDB-show
CHEMBL35063314523451BindingDB-show
CHEMBL3526044283343BindingDB-show
CHEMBL3564322732559BindingDB-show
CHEMBL35731110496022BindingDB-show
CHEMBL3575849840687BindingDB-show
CHEMBL3599544285121BindingDB-show
CHEMBL3638210501144BindingDB-show
CHEMBL36650344386919BindingDB-show
CHEMBL36693710107034BindingDB-show
CHEMBL36717444383743BindingDB-show
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CHEMBL3705210744617BindingDB-show
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CHEMBL3745610669956BindingDB-show
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CHEMBL37993511589433BindingDB-show
CHEMBL37995011515677BindingDB-show
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CHEMBL38906144422282BindingDB-show
CHEMBL3938444285271BindingDB-show
CHEMBL3971410719503BindingDB-show
CHEMBL3977710648756BindingDB-show
CHEMBL3981210829413BindingDB-show
CHEMBL3982811754555BindingDB-show
CHEMBL3988710791459BindingDB-show
CHEMBL3999710763731BindingDB-show
CHEMBL4002810426451BindingDB-show
CHEMBL4016810505477BindingDB-show
CHEMBL41098044273029BindingDB-show
CHEMBL4159679913857BindingDB-show
CHEMBL41623410696749BindingDB-show
CHEMBL41652244267359BindingDB-show
CHEMBL41732644283344BindingDB-show
CHEMBL41750710528823BindingDB-show
CHEMBL41828314054185BindingDB-show
CHEMBL41870444266520BindingDB-show
CHEMBL41873844272739BindingDB-show
CHEMBL41895944325082BindingDB-show
CHEMBL41930544318799BindingDB-show
CHEMBL41983914390779BindingDB-show
CHEMBL42025344324644BindingDB-show
CHEMBL42170214390738BindingDB-show
CHEMBL42292544384275BindingDB-show
CHEMBL42357444364784BindingDB-show
CHEMBL42487711495237BindingDB-show
CHEMBL42538344400757BindingDB-show
CHEMBL433709810328BindingDB-show
CHEMBL43420810740493BindingDB-show
CHEMBL43950811515875BindingDB-show
CHEMBL44233744458316BindingDB-show
CHEMBL44639310768671BindingDB-show
CHEMBL44809810518365BindingDB-show
CHEMBL4728914557662BindingDB-show
CHEMBL48794125015303BindingDB-show
CHEMBL50742044580458BindingDB-show
CHEMBL5171544295334BindingDB-show
CHEMBL5299514134562BindingDB-show
CHEMBL5314144298316BindingDB-show
CHEMBL5362144298401BindingDB-show
CHEMBL5367844298402BindingDB-show
CHEMBL5445744298355BindingDB-show
CHEMBL5447744298426BindingDB-show
CHEMBL5449614134587BindingDB-show
CHEMBL5460144298353BindingDB-show
CHEMBL5479644298428BindingDB-show
CHEMBL5482344298205BindingDB-show
CHEMBL5494244298467BindingDB-show
CHEMBL5503614134578BindingDB-show
CHEMBL5505614134593BindingDB-show
CHEMBL5510310014925BindingDB-show
CHEMBL552869905282BindingDB-show
CHEMBL5552044298529BindingDB-show
CHEMBL5558344298403BindingDB-show
CHEMBL5561344298431BindingDB-show
CHEMBL5572144298400BindingDB-show
CHEMBL5605414134565BindingDB-show
CHEMBL56762844626710BindingDB-show
CHEMBL57070444628063BindingDB-show
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CHEMBL57072244628064BindingDB-show
CHEMBL57073244626711BindingDB-show
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CHEMBL57081144627960BindingDB-show
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CHEMBL5985622732589BindingDB-show
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CHEMBL6101610204512BindingDB-show
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CHEMBL6700010330979BindingDB-show
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CHEMBL9887622874526BindingDB-show
CHEMBL9913244329534BindingDB-show
CHEMBL996344266477BindingDB-show
CHEMBL9986122874513BindingDB-show
CID 1007263010321691BindingDB-show
CID 1016034010160340BindingDB-show
CID 1016034010455810BindingDB-show
CID 1017842810110899BindingDB-show
CID 1040984510364792BindingDB-show
CID 1041161610072629BindingDB-show
CID 1045466810093438BindingDB-show
CID 1047630510046773BindingDB-show
CID 1061778910689164BindingDB-show
CID 1066453810664538BindingDB-show
CID 1113331411811641BindingDB-show
CID 99825849982584BindingDB-show
CID 998291215518149BindingDB-show
CID 998291210163252BindingDB-show
Hcbp-gly124786BindingDB-show
N-(3-PHENYL-2-SULFANYLPROPANOYL)PHENYLALANYLALANINE448249DrugBank-show
N-[3-[(1-AMINOETHYL)(HYDROXY)PHOSPHORYL]-2-(1,1'-BIPHENYL-4-YLMETHYL)PROPANOYL]ALANINE5478838DrugBank-show
n4-hydroxy-n1-{1-[2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-2020BindingDB-show
Omapatrilat656629BindingDB-show
PHOSPHORAMIDON445114BindingDB-show
Phosphoramidon439265DrugBank-show
PHOSPHORAMIDON445114DrugBank-show
PHOSPHORAMIDON445114PROMISCUOUSPMID 8223885show
Phosphoramidon439265PROMISCUOUSPMID 8223885show
Racecadotril107751SuperTarget2 PMIDsshow
SCH 326155486715BindingDB-show
SQ 28603123742BindingDB-show
Thiorphan3132BindingDB-show
Thiorphan3132DrugBank-show
Trihydroxypropane753SuperTarget-show
Zincov22099199BindingDB-show
[(2s)-2-({3-[hydroxyl(2-Phenyl-(1r)-1-{[(Benzyloxy)[(2s)-2-({3-[hydroxyl(211556698BindingDB-show
[2(R,S)-2-SULFANYLHEPTANOYL]-PHE-ALA5289469DrugBank-show
Synonyms:
Atriopeptidase
CALLA
CD10
Common acute lymphocytic leukemia antigen
Enkephalinase
NEP
Neprilysin
Neutral endopeptidase
Neutral endopeptidase 24.11
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
NEP_RAT97.994.3
NEP_MOUSE97.794.1
ECE1_RAT5637.2
PBPA_CLOPE33.218
GYRA_HAEIN3217.2
NCPR_RAT31.617.4
ACSL3_HUMAN31.317.6
KAR3_YEAST31.217.6
ENPL_CANFA3117
AMPD1_HUMAN30.916.8
ENPL_HUMAN30.717.1
IF2P_METTH30.716.3
K6PL_RAT30.416.9
GUNG_CLOCE30.416.7
NCPR_RABIT30.318
NCPR_HUMAN30.317.7
ILVB_YEAST30.217.4
LDLR_MOUSE30.217.3
AMPN_HUMAN30.216.8
CAN_SCHMA3017.1
PLOD2_HUMAN29.916.9
P77847_CALSA29.916.6
GYRB_STAAU29.815.1
METE_THEMA29.816.3
SECA_BACSU29.815.4
PYGM_HUMAN29.718.2
O26085_HELPY29.716.7
HSF_KLULA29.717.5
Q8IDF9_PLAF729.518.3
PERE_HUMAN29.315.4
Protein-Protein Interactions: