Target Details

Name:	Mitogen-activated protein kinase 1
Uniprot name:	MK01_RAT
Accession Numbers:	P27703 P63086
EC-Number:	2.7.11.24
Organism:	Rat Rattus norvegicus
PDB IDs:	1ERK 1GOL 2ERK 2FYS 2GPH 2Z7L 3C9W 3ERK 4ERK
KEGG Pathways:	show KEGG Pathways
Drugs:	Name PubChem ID Source References Interaction BATIMASTAT 5362422 PROMISCUOUS PMID 11025397 show fluindostatin 446155 PROMISCUOUS PMID 15591221 show Fluindostatin 1548972 PROMISCUOUS PMID 15591221 show Mevalonate 439230 PROMISCUOUS PMID 15591221 show Olomoucine 4592 DrugBank - show PHOSPHONOTHREONINE 3246323 DrugBank - show Rosigilitazone 77999 PROMISCUOUS PMID 16155101 show enlarge table
Synonyms:	ERK-2 ERT1 Extracellular signal-regulated kinase 2 MAP kinase 2 MAPK 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 2 p42-MAPK enlarge table
Similar targets:	Uniprot name % Sequence similarity % Sequence identity MK01_MOUSE 100 100 MK01_HUMAN 98.9 98.6 Q1HBJ4_HUMAN 98.9 98.6 Q499G7_HUMAN 98.6 98.1 MK03_HUMAN 88.1 82.3 MK03_MOUSE 87.7 81.6 MK03_RAT 87.7 81.6 MK14_HUMAN 64.1 45.7 MK14_MOUSE 63.8 45.7 MK12_HUMAN 60.4 40.2 MK10_HUMAN 48.3 31.8 CDK6_HUMAN 46.7 31.4 A4D1G0_HUMAN 46.7 31.4 MSK1_TOBAC 46.6 26.9 CDK2_HUMAN 46.6 31.4 CDK7_HUMAN 45.4 33.2 CDC2H_PLAFK 44.4 32 CDK1_HUMAN 44.2 30.4 CDK5_MOUSE 43.8 29.2 CDK5_HUMAN 43.4 29.1 CDK4_HUMAN 42.9 29.1 GSK3B_HUMAN 42.6 27.1 CDK9_HUMAN 42.5 29.7 CSK2A_MAIZE 42.5 24.9 Q5KU03_MOUSE 42.4 27.1 GSK3B_MOUSE 42.4 27.1 B5BUC0_HUMAN 42.1 26.8 C4R3V7_PICPG 41.8 27.7 CDK4_RAT 41.7 28.3 CSK21_HUMAN 41.5 25 enlarge table
Protein-Protein Interactions:	No data available enlarge table

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