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Target Details

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Name:Histone deacetylase 8
Uniprot name:HDAC8_HUMAN
Accession Numbers:A6NET3 Q9BY41 Q9NP76 Q9NYH4
EC-Number:3.5.1.98
Organism:Homo sapiens
Human
PDB IDs:1T64 1T67 1T69 1VKG 1W22 2V5W 2V5X 3EW8 3EWF 3EZP 3EZT 3F06 3F07 3F0R
KEGG Pathways:-
Drugs:
NamePubChem IDSourceReferencesInteraction
()-oxazepam hemisuccinate sodium salt45483433BindingDB-show
()-oxazepam hemisuccinate sodium salt45483434BindingDB-show
()-oxazepam hemisuccinate sodium salt45483435BindingDB-show
1-Naphthohydroxamic acid23382BindingDB-show
4-dimethylamino-N-(7-hydroxy-7-nitrosoheptyl)benzamide5287735DrugBank-show
4-phenylimidazole, 1724853793BindingDB-show
A 3006376322BindingDB-show
AC1OCG0B6918878BindingDB-show
Acetyldinaline2746BindingDB-show
apicidin467801BindingDB-show
benzamide-type inhibitor, 2023648267BindingDB-show
benzamide-type inhibitor, 2111393847BindingDB-show
benzamide-type inhibitor, 2323648268BindingDB-show
benzamide-type inhibitor, 423648260BindingDB-show
benzimidazole analogue, 1824853792BindingDB-show
bis-amide inhibitor, 1516036765BindingDB-show
CHEBI:54708844593387BindingDB-show
CHEMBL108308646890583BindingDB-show
CHEMBL108343811184660BindingDB-show
CHEMBL108343911449246BindingDB-show
CHEMBL108344011426781BindingDB-show
CHEMBL108344111381650BindingDB-show
CHEMBL108374211452638BindingDB-show
CHEMBL108705346881225BindingDB-show
CHEMBL108873446180760BindingDB-show
CHEMBL108873646180763BindingDB-show
CHEMBL109147446180758BindingDB-show
CHEMBL109147546180759BindingDB-show
CHEMBL109303346197798BindingDB-show
CHEMBL109333546197799BindingDB-show
CHEMBL109407746887212BindingDB-show
CHEMBL10940859998313BindingDB-show
CHEMBL109409411430535BindingDB-show
CHEMBL109415246887026BindingDB-show
CHEMBL109415946887060BindingDB-show
CHEMBL109464846887094BindingDB-show
CHEMBL109470746179732BindingDB-show
CHEMBL109470946179779BindingDB-show
CHEMBL109471046179780BindingDB-show
CHEMBL109479246887022BindingDB-show
CHEMBL109479346887023BindingDB-show
CHEMBL109479446887024BindingDB-show
CHEMBL109507510340474BindingDB-show
CHEMBL10950769999602BindingDB-show
CHEMBL109508546887282BindingDB-show
CHEMBL109511846887178BindingDB-show
CHEMBL109511946887179BindingDB-show
CHEMBL109512046887180BindingDB-show
CHEMBL109512446887025BindingDB-show
CHEMBL109513546887093BindingDB-show
CHEMBL109513646887127BindingDB-show
CHEMBL109540011177718BindingDB-show
CHEMBL109543711270791BindingDB-show
CHEMBL109544946887061BindingDB-show
CHEMBL109545011259022BindingDB-show
CHEMBL109545111223999BindingDB-show
CHEMBL109571046887557BindingDB-show
CHEMBL109571146887558BindingDB-show
CHEMBL109571811326181BindingDB-show
CHEMBL109571911360420BindingDB-show
CHEMBL109576410068980BindingDB-show
CHEMBL109576546887062BindingDB-show
CHEMBL109597211166750BindingDB-show
CHEMBL109602246887559BindingDB-show
CHEMBL109603346887241BindingDB-show
CHEMBL109603411199235BindingDB-show
CHEMBL109609346887128BindingDB-show
CHEMBL109643211430412BindingDB-show
CHEMBL109643311212396BindingDB-show
CHEMBL109670511441977BindingDB-show
CHEMBL109698246887919BindingDB-show
CHEMBL109698646861823BindingDB-show
CHEMBL109701710381402BindingDB-show
CHEMBL109736946887556BindingDB-show
CHEMBL109776146886950BindingDB-show
CHEMBL109798110090483BindingDB-show
CHEMBL10980429860473BindingDB-show
CHEMBL109806746887332BindingDB-show
CHEMBL109837910266393BindingDB-show
CHEMBL109904811396478BindingDB-show
CHEMBL109904946887211BindingDB-show
CHEMBL109905746887584BindingDB-show
CHEMBL109905846887585BindingDB-show
CHEMBL109906546887283BindingDB-show
CHEMBL109909410362929BindingDB-show
CHEMBL109909546886948BindingDB-show
CHEMBL109909646886949BindingDB-show
CHEMBL116467146907409BindingDB-show
CHEMBL116997846897943BindingDB-show
CHEMBL117122849798604BindingDB-show
CHEMBL121475946916092BindingDB-show
CHEMBL121476046916093BindingDB-show
CHEMBL121476146916094BindingDB-show
CHEMBL121476246913905BindingDB-show
CHEMBL121476346913906BindingDB-show
CHEMBL13787544359555BindingDB-show
CHEMBL13809044359814BindingDB-show
CHEMBL13829344359800BindingDB-show
CHEMBL13862644359673BindingDB-show
CHEMBL13919244359674BindingDB-show
CHEMBL13919344359675BindingDB-show
CHEMBL1405259891541BindingDB-show
CHEMBL14108244359788BindingDB-show
CHEMBL14188544359548BindingDB-show
CHEMBL14190944359547BindingDB-show
CHEMBL15451744369352BindingDB-show
CHEMBL15688717748273BindingDB-show
CHEMBL17845616733414BindingDB-show
CHEMBL18006416733590BindingDB-show
CHEMBL18091111267278BindingDB-show
CHEMBL18800744395329BindingDB-show
CHEMBL21664111664499BindingDB-show
CHEMBL22711816733295BindingDB-show
CHEMBL22711916733415BindingDB-show
CHEMBL22712011558827BindingDB-show
CHEMBL22717016733417BindingDB-show
CHEMBL23690216066811BindingDB-show
CHEMBL24253317756401BindingDB-show
CHEMBL24554824880249BindingDB-show
CHEMBL25114416006672BindingDB-show
CHEMBL25386825155417BindingDB-show
CHEMBL26993544454650BindingDB-show
CHEMBL3369359848223BindingDB-show
CHEMBL33758444359538BindingDB-show
CHEMBL34371744359681BindingDB-show
CHEMBL36352844395330BindingDB-show
CHEMBL36375010326820BindingDB-show
CHEMBL38792416733411BindingDB-show
CHEMBL38819516220721BindingDB-show
CHEMBL38968716733294BindingDB-show
CHEMBL38968816733410BindingDB-show
CHEMBL39045217756403BindingDB-show
CHEMBL39842025032862BindingDB-show
CHEMBL39949425155956BindingDB-show
CHEMBL40072144447194BindingDB-show
CHEMBL42713516733416BindingDB-show
CHEMBL42751016733412BindingDB-show
CHEMBL44001811279156BindingDB-show
CHEMBL44651224948907BindingDB-show
CHEMBL44681125152062BindingDB-show
CHEMBL44949342638005BindingDB-show
CHEMBL45402525151110BindingDB-show
CHEMBL45534225151675BindingDB-show
CHEMBL45573525151864BindingDB-show
CHEMBL46621511657529BindingDB-show
CHEMBL46664444574084BindingDB-show
CHEMBL46779224948905BindingDB-show
CHEMBL46779324948908BindingDB-show
CHEMBL46799824951311BindingDB-show
CHEMBL46851316049824BindingDB-show
CHEMBL46859524948906BindingDB-show
CHEMBL46884124948909BindingDB-show
CHEMBL46884224948910BindingDB-show
CHEMBL46918724825455BindingDB-show
CHEMBL46927424951312BindingDB-show
CHEMBL46927524951313BindingDB-show
CHEMBL47022542601485BindingDB-show
CHEMBL47084344592059BindingDB-show
CHEMBL47104144138031BindingDB-show
CHEMBL47104244138032BindingDB-show
CHEMBL47104344138033BindingDB-show
CHEMBL47225025113671BindingDB-show
CHEMBL47263144591988BindingDB-show
CHEMBL47984216661613BindingDB-show
CHEMBL48072916661615BindingDB-show
CHEMBL48101816659535BindingDB-show
CHEMBL48153816659537BindingDB-show
CHEMBL48171844571330BindingDB-show
CHEMBL48171944571331BindingDB-show
CHEMBL48172644571332BindingDB-show
CHEMBL48180216661455BindingDB-show
CHEMBL48180525195084BindingDB-show
CHEMBL48235844571302BindingDB-show
CHEMBL48407342599456BindingDB-show
CHEMBL4844899923508BindingDB-show
CHEMBL4855149924543BindingDB-show
CHEMBL49001842599455BindingDB-show
CHEMBL49044625152063BindingDB-show
CHEMBL49113042637299BindingDB-show
CHEMBL49192642638004BindingDB-show
CHEMBL49209742637372BindingDB-show
CHEMBL49214042637300BindingDB-show
CHEMBL49217442637373BindingDB-show
CHEMBL49890825190760BindingDB-show
CHEMBL49999425151865BindingDB-show
CHEMBL50164025150907BindingDB-show
CHEMBL50243025152061BindingDB-show
CHEMBL50311325150908BindingDB-show
CHEMBL50404025151497BindingDB-show
CHEMBL50683425151496BindingDB-show
CHEMBL50761725151676BindingDB-show
CHEMBL50908925190758BindingDB-show
CHEMBL51080625151109BindingDB-show
CHEMBL51174924951314BindingDB-show
CHEMBL51316024951310BindingDB-show
CHEMBL51660016661458BindingDB-show
CHEMBL51895716661454BindingDB-show
CHEMBL51994316661453BindingDB-show
CHEMBL52143116661617BindingDB-show
CHEMBL56148311993694BindingDB-show
CHEMBL56160445269423BindingDB-show
CHEMBL56438211993595BindingDB-show
CHEMBL56487611993691BindingDB-show
CHEMBL56491645271073BindingDB-show
CHEMBL56664144598479BindingDB-show
CHEMBL56680744598347BindingDB-show
CHEMBL56681744598386BindingDB-show
CHEMBL56745744598289BindingDB-show
CHEMBL56815144598388BindingDB-show
CHEMBL56912244598482BindingDB-show
CHEMBL56921144598288BindingDB-show
CHEMBL56928844598344BindingDB-show
CHEMBL56930644598345BindingDB-show
CHEMBL56944644598290BindingDB-show
CHEMBL56944744598385BindingDB-show
CHEMBL56967444598431BindingDB-show
CHEMBL56981244598480BindingDB-show
CHEMBL56994645485820BindingDB-show
CHEMBL57049042612852BindingDB-show
CHEMBL57114044598481BindingDB-show
CHEMBL57204444598483BindingDB-show
CHEMBL57237445484125BindingDB-show
CHEMBL58313042611300BindingDB-show
CHEMBL58516444550557BindingDB-show
CHEMBL58593942611301BindingDB-show
CHEMBL58924646228613BindingDB-show
CHEMBL58930346228882BindingDB-show
CHEMBL58930446228883BindingDB-show
CHEMBL59148446228885BindingDB-show
CHEMBL59149446228941BindingDB-show
CHEMBL59171646228886BindingDB-show
CHEMBL59244046228937BindingDB-show
CHEMBL59660346228504BindingDB-show
CHEMBL59678346228609BindingDB-show
CHEMBL59698646228580BindingDB-show
CHEMBL59700346228450BindingDB-show
CHEMBL59718946228582BindingDB-show
CHEMBL59779946228543BindingDB-show
CHEMBL59799846228546BindingDB-show
CHEMBL59799946228547BindingDB-show
CHEMBL59843046228639BindingDB-show
CHEMBL59861846228522BindingDB-show
CHEMBL59903746228610BindingDB-show
CHEMBL59943146228518BindingDB-show
CHEMBL59943246228521BindingDB-show
CHEMBL59946046228451BindingDB-show
CHEMBL59946146228453BindingDB-show
CHEMBL59946246228454BindingDB-show
CHEMBL59967346228501BindingDB-show
CHEMBL59967446228503BindingDB-show
CHEMBL60007246228940BindingDB-show
CHEMBL60275746228938BindingDB-show
CHEMBL60409746228544BindingDB-show
CHEMBL60417846228637BindingDB-show
CHEMBL60492046228500BindingDB-show
CHEMBL60511746228579BindingDB-show
CHEMBL60618846228612BindingDB-show
CHEMBL60639746228638BindingDB-show
CHEMBL60874146228519BindingDB-show
CHEMBL60958310309899BindingDB-show
CHEMBL61077746228583BindingDB-show
CID 1168250211682502BindingDB-show
Dacinostat6445533BindingDB-show
Entinostat4261BindingDB-show
MGCD-01039865515BindingDB-show
N-hydroxy-3-phenoxy-benzamide10192705BindingDB-show
N-HYDROXY-4-(METHYL{[5-(2-PYRIDINYL)-2-THIENYL]SULFONYL}AMINO)BENZAMIDE449096DrugBank-show
NSC44620239512BindingDB-show
S1090_Selleck11749858BindingDB-show
S1194_Selleck24756910BindingDB-show
SB-6396918877BindingDB-show
Scriptaid5186BindingDB-show
STK156256785232BindingDB-show
Suberanilohydroxamic acid5311BindingDB-show
Suberanilohydroxamic acid5311DrugBank-show
Triazole Ligand, 10a24881330BindingDB-show
Triazole Ligand, 10b24881405BindingDB-show
Triazole Ligand, 10c24881331BindingDB-show
Triazole Ligand, 10d24881406BindingDB-show
Triazole Ligand, 12a24881407BindingDB-show
Triazole Ligand, 12b24881332BindingDB-show
Triazole Ligand, 12c24881464BindingDB-show
Triazole Ligand, 12d24881333BindingDB-show
Triazole Ligand, 14a24881402BindingDB-show
Triazole Ligand, 14b24881465BindingDB-show
Triazole Ligand, 14c24881403BindingDB-show
Triazole Ligand, 14d24881466BindingDB-show
Triazole Ligand, 6a24881257BindingDB-show
Triazole Ligand, 6b24881328BindingDB-show
Triazole Ligand, 6c24881404BindingDB-show
Triazole Ligand, 6d24881329BindingDB-show
Trichlostatin A444732BindingDB-show
Trichlostatin A444732DrugBank-show
Trichlostatin A444732PROMISCUOUSPMID 18059533show
Tubacin6675804BindingDB-show
Synonyms:
HD8
Histone deacetylase 8
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
HDAC3_MOUSE52.234.7
HDAC3_HUMAN51.734.4
Q7KTS4_DROME49.331.6
HDAC1_HUMAN47.830.8
HDAC2_HUMAN47.530.7
O67135_AQUAE47.329.4
Q8T7M1_PHYPO37.824.9
CYSEP_RICCO33.117.3
Q9X0L5_THEMA32.618.7
CISY_PYRFU32.619.1
ENO_ENTHR31.618.7
DCUP_MOUSE31.519.4
IADA_ECOLI31.417.9
PURT_ECOLI31.117.9
CARP_YEAST31.121.1
DEGS_BREBE31.115.5
7OMT8_MEDSA30.817.2
KCNK1_HUMAN30.516.4
ADH_THEBR30.418.1
Q9LCX9_THETH30.417.3
DHB7_HUMAN30.215.8
GSHB_HUMAN30.216.3
PIM1_HUMAN30.117.2
Q99MI5_RAT30.118.5
FPPS_HUMAN3017.3
CYH2_RAT29.917.3
PDK2_MOUSE29.813.8
PAPA1_CARPA29.815.6
DCUP_HUMAN29.817.4
FPPS_CHICK29.716.3
Protein-Protein Interactions: