Target Details

Name:

Glutathione S-transferase P

Uniprot name:

GSTP1_HUMAN

Accession Numbers:

O00460 P09211 Q15690 Q5TZY3

EC-Number:

2.5.1.18

Organism:

Homo sapiens
Human

PDB IDs:

10GS 11GS 12GS 13GS 14GS 16GS 17GS 18GS 19GS 1AQV 1AQW 1AQX 1EOG 1EOH 1GSS 1KBN 1LBK 1MD3 1MD4 1PGT 1PX6 1PX7 1ZGN 20GS 22GS 2A2R 2A2S 2GSS 2J9H 2PGT 3CSH 3CSI 3CSJ 3DD3 3DGQ 3GSS 3HJM 3HJO 3HKR 3PGT 4GSS 4PGT 5GSS 6GSS 7GSS 8GSS 9GSS

KEGG Pathways:

show KEGG Pathways

Drugs:

Name	PubChem ID	Source	References	Interaction
2-(N-morpholiniumyl)ethanesulfonate	4478249	DrugBank	-	show
2-Comc	6439061	BindingDB	-	show
9R,10R-9-GLUTATHIONYL-10-HYDROXY-9,10-DIHYDRO PHENANTHRENE	449366	DrugBank	-	show
AC1L4IDA	157619	BindingDB	-	show
AC1N9J6O	4411483	BindingDB	-	show
CHEBI:675574	45484261	BindingDB	-	show
CHEMBL109304	10447087	BindingDB	-	show
CHEMBL113408	10422367	BindingDB	-	show
CHEMBL174379	44387048	BindingDB	-	show
CHEMBL174893	44385932	BindingDB	-	show
CHEMBL174957	44386040	BindingDB	-	show
CHEMBL175098	44385682	BindingDB	-	show
CHEMBL176294	44386941	BindingDB	-	show
CHEMBL176946	44386993	BindingDB	-	show
CHEMBL195934	44403943	BindingDB	-	show
CHEMBL196798	13885287	BindingDB	-	show
CHEMBL197468	14132141	BindingDB	-	show
CHEMBL197993	44404193	BindingDB	-	show
CHEMBL209755	44413517	BindingDB	-	show
CHEMBL211727	44413514	BindingDB	-	show
CHEMBL211916	44413516	BindingDB	-	show
CHEMBL212097	44413512	BindingDB	-	show
CHEMBL212517	44413511	BindingDB	-	show
CHEMBL212685	44413513	BindingDB	-	show
CHEMBL216505	44413967	BindingDB	-	show
CHEMBL301229	11743150	BindingDB	-	show
CHEMBL359933	44386723	BindingDB	-	show
CHEMBL369465	44387218	BindingDB	-	show
CHEMBL379437	44413518	BindingDB	-	show
CHEMBL426936	44385619	BindingDB	-	show
CHEMBL441308	44386041	BindingDB	-	show
CHEMBL442360	44300905	BindingDB	-	show
CHEMBL565458	25019871	BindingDB	-	show
CHEMBL565718	45484285	BindingDB	-	show
CHEMBL566519	45484220	BindingDB	-	show
CHEMBL566962	25019608	BindingDB	-	show
CHEMBL568260	25019607	BindingDB	-	show
CHEMBL568269	25019869	BindingDB	-	show
CHEMBL568724	45484201	BindingDB	-	show
CHEMBL568725	25019870	BindingDB	-	show
CHEMBL568727	45484253	BindingDB	-	show
CHEMBL569196	45484212	BindingDB	-	show
CHEMBL569199	25019874	BindingDB	-	show
CHEMBL569653	45484207	BindingDB	-	show
CHEMBL569891	45484257	BindingDB	-	show
CHEMBL569892	45484259	BindingDB	-	show
CHEMBL570107	45484226	BindingDB	-	show
CHEMBL571050	45484206	BindingDB	-	show
CHEMBL571052	25019609	BindingDB	-	show
CHEMBL571257	45484234	BindingDB	-	show
CHEMBL571473	45484276	BindingDB	-	show
CHEMBL571474	25019875	BindingDB	-	show
CHEMBL571488	45484242	BindingDB	-	show
CHEMBL576684	45484258	BindingDB	-	show
CHEMBL576873	45484248	BindingDB	-	show
CHEMBL577307	45484227	BindingDB	-	show
CHEMBL579208	45484221	BindingDB	-	show
CHEMBL582827	45484241	BindingDB	-	show
CHEMBL582973	45484217	BindingDB	-	show
CHEMBL584306	45484202	BindingDB	-	show
CHEMBL58451	44300921	BindingDB	-	show
CHEMBL58507	44300893	BindingDB	-	show
CHEMBL58951	20731911	BindingDB	-	show
CHEMBL60581	44300879	BindingDB	-	show
Chloraminophene	2708	SuperTarget	-	show
CIBACRON BLUE	172469	DrugBank	-	show
gamma-Glutamylcysteinylglycine	124886	DrugBank	-	show
gamma-Glutamylcysteinylglycine	124886	SuperTarget	-	show
Methylenebutyrylphenoxyacetic acid	3278	BindingDB	-	show
Methylenebutyrylphenoxyacetic acid	3278	DrugBank	-	show
Methylenebutyrylphenoxyacetic acid	3278	PROMISCUOUS	PMID 14556662	show
Methylenebutyrylphenoxyacetic acid	3278	SuperTarget	-	show
Monochlorimipramine	2801	DrugBank	-	show
Mononitrogen monoxide	945	SuperTarget	-	show
NSC131114	5141	BindingDB	-	show
S-(2,4-Dinitrophenyl)glutathione	97535	DrugBank	-	show
S-HEXYLGLUTATHIONE	445875	DrugBank	-	show
Salicylazosulfapyridine	5353980	SuperTarget	-	show
Trichloraethylenum	6575	SuperTarget	-	show
Trihydroxypropane	753	DrugBank	-	show
Trihydroxypropane	753	SuperTarget	-	show

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Synonyms:

Glutathione S-transferase P

GST class-pi

GSTP1-1

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Similar targets:

Uniprot name	% Sequence similarity	% Sequence identity
GSTP1_MOUSE	93.8	85.2
C7DJS1_HUMAN	71.9	71.9
C7DJS2_HUMAN	71.9	71.4
GSTP_ONCVO	59.7	41.7
GSTM2_RAT	49.6	28.1
GSTM2_HUMAN	48.9	30.7
GSTM3_HUMAN	48.5	29.7
GSTM4_HUMAN	48.4	29.3
GSTM5_HUMAN	48.2	29
GSTM1_RAT	48	28.3
GSTM2_CHICK	48	28
GSTA1_RAT	47.6	29.2
GST26_SCHJA	47.5	27.8
GSTA4_MOUSE	47.3	30.1
GSTA2_MOUSE	47.2	29.2
GSTA1_HUMAN	47.1	27.8
GSTM1_HUMAN	47.1	28.4
GSTA1_MOUSE	47	28
GSTA3_HUMAN	46.7	28.8
GSTA5_HUMAN	46.3	26.4
GST_OMMSL	46.3	30.7
GSTA2_HUMAN	45.5	26.6
GST_PLAFA	45.2	25.4
GSTA4_HUMAN	43.8	27.1
GST_ECOLI	40.5	18.5
MAAI_HUMAN	39.8	22
GST28_SCHBO	38.9	19.7
HPGDS_HUMAN	37.5	22.1
GSTO1_HUMAN	37.5	20.5
Q7CL96_YERPE	37.1	22.5

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Protein-Protein Interactions:

Uniprot name	Source
TGM2_HUMAN	PMID 9973324
SUMO4_HUMAN	2 PMIDs
PTN_HUMAN	3 PMIDs
PNO1_HUMAN	4 PMIDs
M3K5_HUMAN	5 PMIDs
GSTP1_HUMAN	6 PMIDs

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