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Target Details

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Name:Endothelin-1 receptor
Uniprot name:EDNRA_HUMAN
Accession Numbers:B2R723 O43441 P25101 Q16432 Q16433 Q8TBH2
EC-Number:-
Organism:Homo sapiens
Human
PDB IDs:-
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
()-oxazepam hemisuccinate sodium salt44340523BindingDB-show
()-oxazepam hemisuccinate sodium salt44311286BindingDB-show
()-oxazepam hemisuccinate sodium salt44368819BindingDB-show
()-oxazepam hemisuccinate sodium salt44368906BindingDB-show
()-oxazepam hemisuccinate sodium salt44368824BindingDB-show
()-oxazepam hemisuccinate sodium salt44368903BindingDB-show
()-oxazepam hemisuccinate sodium salt44369088BindingDB-show
()-oxazepam hemisuccinate sodium salt44368943BindingDB-show
()-oxazepam hemisuccinate sodium salt44368812BindingDB-show
()-oxazepam hemisuccinate sodium salt44368904BindingDB-show
()-oxazepam hemisuccinate sodium salt44371616BindingDB-show
()-oxazepam hemisuccinate sodium salt44371798BindingDB-show
()-oxazepam hemisuccinate sodium salt44371795BindingDB-show
()-oxazepam hemisuccinate sodium salt46878642BindingDB-show
()-oxazepam hemisuccinate sodium salt46878641BindingDB-show
2,5-dichloro-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide3795752BindingDB-show
4-bromo-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide3811690BindingDB-show
5-Ddins122272BindingDB-show
740873-06-711430856BindingDB-show
A-1820869916235BindingDB-show
A1277225310990BindingDB-show
A1926215310991BindingDB-show
Ac-Dip-leu-asp-ile-ile-trp122149BindingDB-show
AC1MCYL02802888BindingDB-show
Ambrisentan197712BindingDB-show
Ambrisentan6918493BindingDB-show
Ambrisentan6918493PROMISCUOUSPMID 18238950show
Ambrisentan197712PROMISCUOUSPMID 18238950show
Atrasentan159594BindingDB-show
BMS-20794044275660BindingDB-show
Bosentan104865BindingDB-show
Bosentan104865DrugBank-show
Bosentan104865PROMISCUOUSPMID 18238950show
Bosentan104865SuperTargetPMID 16741059show
BOSENTAN SODIUM44387533BindingDB-show
BQ123443289BindingDB-show
CHEBI:65070644284289BindingDB-show
CHEMBL10000544332656BindingDB-show
CHEMBL10012044332624BindingDB-show
CHEMBL100169850566BindingDB-show
CHEMBL1001944266594BindingDB-show
CHEMBL10075621559921BindingDB-show
CHEMBL10079544213651BindingDB-show
CHEMBL10087444332578BindingDB-show
CHEMBL1009244266537BindingDB-show
CHEMBL10095410624645BindingDB-show
CHEMBL10106910648996BindingDB-show
CHEMBL10123944332638BindingDB-show
CHEMBL10129244332650BindingDB-show
CHEMBL1013644266595BindingDB-show
CHEMBL10142444334128BindingDB-show
CHEMBL1014314673588BindingDB-show
CHEMBL1015144266629BindingDB-show
CHEMBL10158711799973BindingDB-show
CHEMBL10174210553793BindingDB-show
CHEMBL1021144266532BindingDB-show
CHEMBL10217344334130BindingDB-show
CHEMBL1021844266552BindingDB-show
CHEMBL10230711799974BindingDB-show
CHEMBL10231444334150BindingDB-show
CHEMBL10234844333055BindingDB-show
CHEMBL10241144334053BindingDB-show
CHEMBL10249410452089BindingDB-show
CHEMBL10277344333578BindingDB-show
CHEMBL10279711800649BindingDB-show
CHEMBL10286810528863BindingDB-show
CHEMBL10296910321290BindingDB-show
CHEMBL10300144333867BindingDB-show
CHEMBL1030244266575BindingDB-show
CHEMBL10309044334145BindingDB-show
CHEMBL10319010505434BindingDB-show
CHEMBL10320110840560BindingDB-show
CHEMBL10330821559928BindingDB-show
CHEMBL10336244332777BindingDB-show
CHEMBL10348444332577BindingDB-show
CHEMBL10349744332803BindingDB-show
CHEMBL10350115410997BindingDB-show
CHEMBL10357244332823BindingDB-show
CHEMBL10357344332824BindingDB-show
CHEMBL10360510508342BindingDB-show
CHEMBL10363144332775BindingDB-show
CHEMBL10369510555112BindingDB-show
CHEMBL10373144332641BindingDB-show
CHEMBL103749845562BindingDB-show
CHEMBL10384615411005BindingDB-show
CHEMBL10387244332345BindingDB-show
CHEMBL1038844266628BindingDB-show
CHEMBL10388644332623BindingDB-show
CHEMBL10396944332856BindingDB-show
CHEMBL10397544333056BindingDB-show
CHEMBL10417210811477BindingDB-show
CHEMBL10422310835335BindingDB-show
CHEMBL1045744266540BindingDB-show
CHEMBL10484811794992BindingDB-show
CHEMBL1052344266655BindingDB-show
CHEMBL10549010691437BindingDB-show
CHEMBL10549444333889BindingDB-show
CHEMBL10559144333913BindingDB-show
CHEMBL1058810342643BindingDB-show
CHEMBL1058910600668BindingDB-show
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CHEMBL1062210718141BindingDB-show
CHEMBL1063510790686BindingDB-show
CHEMBL1063610695363BindingDB-show
CHEMBL106449957225BindingDB-show
CHEMBL106489980487BindingDB-show
CHEMBL1066110767505BindingDB-show
CHEMBL1066849908909BindingDB-show
CHEMBL10674910740953BindingDB-show
CHEMBL106769913198BindingDB-show
CHEMBL10684610549472BindingDB-show
CHEMBL1069710576427BindingDB-show
CHEMBL1069944266592BindingDB-show
CHEMBL1073311744509BindingDB-show
CHEMBL1074410646372BindingDB-show
CHEMBL1075044266538BindingDB-show
CHEMBL10757410548722BindingDB-show
CHEMBL1078110530409BindingDB-show
CHEMBL1079410503525BindingDB-show
CHEMBL1080144266940BindingDB-show
CHEMBL1080810788853BindingDB-show
CHEMBL10814210745564BindingDB-show
CHEMBL1081910552007BindingDB-show
CHEMBL1083244266886BindingDB-show
CHEMBL1083410671036BindingDB-show
CHEMBL1084310597575BindingDB-show
CHEMBL1084610647021BindingDB-show
CHEMBL1084744266850BindingDB-show
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CHEMBL1086010671928BindingDB-show
CHEMBL1086244266902BindingDB-show
CHEMBL10874810721344BindingDB-show
CHEMBL1089710024044BindingDB-show
CHEMBL1090110765171BindingDB-show
CHEMBL1090544266881BindingDB-show
CHEMBL1091010526002BindingDB-show
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CHEMBL1091510647642BindingDB-show
CHEMBL1091910503067BindingDB-show
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CHEMBL1116210410546BindingDB-show
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CHEMBL1117410670279BindingDB-show
CHEMBL1117610504689BindingDB-show
CHEMBL11176910142669BindingDB-show
CHEMBL11178310791823BindingDB-show
CHEMBL1125319938571BindingDB-show
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CHEMBL11260519074176BindingDB-show
CHEMBL11308710817057BindingDB-show
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CHEMBL1134510815005BindingDB-show
CHEMBL1136910815823BindingDB-show
CHEMBL1152810166561BindingDB-show
CHEMBL11531522461009BindingDB-show
CHEMBL1184020747574BindingDB-show
CHEMBL12010610625269BindingDB-show
CHEMBL1201310209324BindingDB-show
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CHEMBL1210210166104BindingDB-show
CHEMBL121069871837BindingDB-show
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CHEMBL12164744347211BindingDB-show
CHEMBL1217210280562BindingDB-show
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CHEMBL12211110577388BindingDB-show
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CHEMBL12261444347519BindingDB-show
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CHEMBL126910152943235BindingDB-show
CHEMBL126910252943236BindingDB-show
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CHEMBL14790844364522BindingDB-show
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CID 1052770610527706BindingDB-show
CID 1059923010599230BindingDB-show
CID 1060340910603409BindingDB-show
CID 1064893710648937BindingDB-show
CID 1071959810719598BindingDB-show
CID 1104933611113812BindingDB-show
CID 1104933611049336BindingDB-show
CID 1179850411798504BindingDB-show
CID 98119689897720BindingDB-show
CID 98119689811968BindingDB-show
CID 98300989938533BindingDB-show
CID 98300989830098BindingDB-show
CID 989784110463627BindingDB-show
CID 99083719821701BindingDB-show
CID 99150289915028BindingDB-show
CID 99841939984193BindingDB-show
CID 998419310391968BindingDB-show
Clazosentan6433095BindingDB-show
Darusentan177236BindingDB-show
Edonentan [INN]156690BindingDB-show
Feloprentan6433100BindingDB-show
FR 139317107810BindingDB-show
Histidyl-leucyl-aspartyl-isoleucyl-isoleucyl-tryptophan129432BindingDB-show
Hypophyllantin182140BindingDB-show
Irbesartan3749BindingDB-show
LS-1935379895957BindingDB-show
LS-445399843631BindingDB-show
LU-1352529953358BindingDB-show
Maybridge4_0011992809510BindingDB-show
MEGxp0_0018579953821BindingDB-show
N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide3370402BindingDB-show
Nirtetralin10477792BindingDB-show
NITD60944469321BindingDB-show
NSC402957345351BindingDB-show
Oprea1_14886518617407BindingDB-show
Oprea1_40269014973489BindingDB-show
Oprea1_62132315453170BindingDB-show
PDSP2_001716178103BindingDB-show
Phthalhydroquinone289PROMISCUOUSPMID 16741061show
SB-209670108002BindingDB-show
Sitaxsentan216235BindingDB-show
Sitaxsentan216235PROMISCUOUS2 PMIDsshow
STK0550815122650BindingDB-show
STK0803193921421BindingDB-show
Sulfanilamidothiazole5340BindingDB-show
Sulphadimethylisoxazole5344BindingDB-show
Tocris-18385311192BindingDB-show
Synonyms:
Endothelin A receptor
Endothelin-1 receptor
ET-A
ETA-R
hET-AR
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
EDNRA_MOUSE96.392.3
EDNRA_RAT95.892.7
EDNRB_RAT71.153.2
EDNRB_HUMAN68.654.2
EDNRB_RABIT68.352.7
CXCR4_HUMAN38.221.4
5HT2A_HUMAN38.118.8
P2Y12_HUMAN37.920.6
OPRM_HUMAN37.522.7
OPRX_HUMAN37.322.5
MTR1A_HUMAN37.317.8
BKRB2_HUMAN37.121.7
CXCR1_HUMAN37.121.7
Q6FGM5_HUMAN3722.5
PAR1_RAT36.820.3
SSR2_HUMAN36.420.7
Q506J9_HUMAN36.418.8
Q8TBK4_HUMAN36.419.3
OPRK_HUMAN36.122.8
CCR5_HUMAN3618.6
CNR1_HUMAN3619.2
Q6NUP5_HUMAN35.919.3
AGTR1_HUMAN35.919.3
Q53YY0_HUMAN35.919.3
CLTR1_HUMAN35.320.1
SSR5_HUMAN3521.1
P2RY2_HUMAN34.419.7
OPRD_HUMAN34.421.2
NK2R_HUMAN34.318.5
SUCR1_HUMAN34.218.1
Protein-Protein Interactions: