Target Details |  |
| Name: | Bifunctional dihydrofolate reductase-thymidylate synthase | |
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| Uniprot name: | DRTS_PLAFK |
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| Accession Numbers: | P13922 Q27734 |
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| EC-Number: | - |
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| Organism: | isolate K1 / Thailand
Plasmodium falciparum
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| PDB IDs: | 1J3I 1J3J 1J3K 3DG8 3DGA |
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KEGG Pathways: | - | | Drugs: | | Name | PubChem ID | Source | References | Interaction | | (3-hydrazinylquinoxalin-2-yl)hydrazine | 155947 | BindingDB | - | show |
| 1,3,5-Triazine-2,4-diamine, 1,6-dihydro-6,6-dimethyl-1-phenyl- | 19931 | BindingDB | - | show |
| 2,4-Diamino-5-(3-methoxy-4-benzyloxybenzyl)pyrimidine | 463124 | BindingDB | - | show |
| 2,4-Diamino-5-(3-methoxy-4-ethoxybenzyl)pyrimidine | 463109 | BindingDB | - | show |
| 2,4-Diamino-5-(4-methoxybenzyl)pyrimidine | 88462 | BindingDB | - | show |
| 2,4-Diamino-6-ethyl-5-phenylpyrimidine | 93114 | BindingDB | - | show |
| 5-(4-bromophenyl)-6-ethylpyrimidine-2,4-diamine | 134626 | BindingDB | - | show |
| AC1L1TU0 | 35510 | BindingDB | - | show |
| AC1L7FUM | 309795 | BindingDB | - | show |
| AC1L8VI2 | 433474 | BindingDB | - | show |
| AC1LA7IK | 463126 | BindingDB | - | show |
| AC1LA7IQ | 463128 | BindingDB | - | show |
| AC1MJ80Y | 3132813 | BindingDB | - | show |
| AC1NWE6S | 5703862 | BindingDB | - | show |
| AC1NWF7S | 5704385 | BindingDB | - | show |
| AC1NZH75 | 5933236 | BindingDB | - | show |
| Benzylpyrimidine der | 463131 | BindingDB | - | show |
| BRL 6231hydrochloride | 121750 | BindingDB | - | show |
| BRN 0146163 | 134761 | BindingDB | - | show |
| BRN 0172545 | 204821 | BindingDB | - | show |
| CHEMBL115483 | 11383435 | BindingDB | - | show |
| CHEMBL118202 | 11339941 | BindingDB | - | show |
| CHEMBL118425 | 11361827 | BindingDB | - | show |
| CHEMBL118581 | 11403887 | BindingDB | - | show |
| CHEMBL118602 | 11360523 | BindingDB | - | show |
| CHEMBL118652 | 11419251 | BindingDB | - | show |
| CHEMBL118870 | 11289167 | BindingDB | - | show |
| CHEMBL119086 | 11202498 | BindingDB | - | show |
| CHEMBL119188 | 11383848 | BindingDB | - | show |
| CHEMBL119189 | 11278942 | BindingDB | - | show |
| CHEMBL119224 | 11231647 | BindingDB | - | show |
| CHEMBL119568 | 11256615 | BindingDB | - | show |
| CHEMBL119669 | 11738598 | BindingDB | - | show |
| CHEMBL120123 | 9998014 | BindingDB | - | show |
| CHEMBL13636 | 12996853 | BindingDB | - | show |
| CHEMBL158054 | 11185091 | BindingDB | - | show |
| CHEMBL158570 | 11154519 | BindingDB | - | show |
| CHEMBL158639 | 11208245 | BindingDB | - | show |
| CHEMBL158691 | 11818325 | BindingDB | - | show |
| CHEMBL159032 | 11257841 | BindingDB | - | show |
| CHEMBL159040 | 11288025 | BindingDB | - | show |
| CHEMBL159052 | 11180416 | BindingDB | - | show |
| CHEMBL161009 | 11450092 | BindingDB | - | show |
| CHEMBL161034 | 11303895 | BindingDB | - | show |
| CHEMBL161117 | 10271795 | BindingDB | - | show |
| CHEMBL161451 | 11486149 | BindingDB | - | show |
| CHEMBL161673 | 10245546 | BindingDB | - | show |
| CHEMBL161757 | 11351662 | BindingDB | - | show |
| CHEMBL162126 | 11152240 | BindingDB | - | show |
| CHEMBL21395 | 11046337 | BindingDB | - | show |
| CHEMBL21407 | 10266000 | BindingDB | - | show |
| CHEMBL21414 | 23423601 | BindingDB | - | show |
| CHEMBL21494 | 10018953 | BindingDB | - | show |
| CHEMBL21691 | 11121319 | BindingDB | - | show |
| CHEMBL21778 | 11020649 | BindingDB | - | show |
| CHEMBL21885 | 10945514 | BindingDB | - | show |
| CHEMBL21921 | 9974420 | BindingDB | - | show |
| CHEMBL22039 | 13926968 | BindingDB | - | show |
| CHEMBL22129 | 11015286 | BindingDB | - | show |
| CHEMBL22137 | 11048457 | BindingDB | - | show |
| CHEMBL22138 | 11047913 | BindingDB | - | show |
| CHEMBL22139 | 10434110 | BindingDB | - | show |
| CHEMBL22271 | 10905790 | BindingDB | - | show |
| CHEMBL22357 | 10902094 | BindingDB | - | show |
| CHEMBL22403 | 10927461 | BindingDB | - | show |
| CHEMBL22405 | 10426185 | BindingDB | - | show |
| CHEMBL22693 | 9814965 | BindingDB | - | show |
| CHEMBL22811 | 11026309 | BindingDB | - | show |
| CHEMBL22901 | 10365962 | BindingDB | - | show |
| CHEMBL25112 | 11091680 | BindingDB | - | show |
| CHEMBL274031 | 10828475 | BindingDB | - | show |
| CHEMBL278813 | 10090457 | BindingDB | - | show |
| CHEMBL278847 | 10060600 | BindingDB | - | show |
| CHEMBL279509 | 10937436 | BindingDB | - | show |
| CHEMBL279948 | 11026315 | BindingDB | - | show |
| CHEMBL279986 | 11119819 | BindingDB | - | show |
| CHEMBL280410 | 11081653 | BindingDB | - | show |
| CHEMBL291931 | 11450525 | BindingDB | - | show |
| CHEMBL29773 | 10466996 | BindingDB | - | show |
| CHEMBL30937 | 10335810 | BindingDB | - | show |
| CHEMBL324775 | 11175353 | BindingDB | - | show |
| CHEMBL325533 | 9972300 | BindingDB | - | show |
| CHEMBL333779 | 11234309 | BindingDB | - | show |
| CHEMBL345146 | 10914065 | BindingDB | - | show |
| CHEMBL346932 | 11463215 | BindingDB | - | show |
| CHEMBL346963 | 11255710 | BindingDB | - | show |
| CHEMBL346982 | 11428294 | BindingDB | - | show |
| CHEMBL347190 | 11369668 | BindingDB | - | show |
| CHEMBL348151 | 11282588 | BindingDB | - | show |
| CHEMBL351099 | 11188944 | BindingDB | - | show |
| CHEMBL352195 | 11224057 | BindingDB | - | show |
| CHEMBL352441 | 10476801 | BindingDB | - | show |
| CHEMBL354011 | 11750096 | BindingDB | - | show |
| CHEMBL416373 | 11091885 | BindingDB | - | show |
| CHEMBL416376 | 11732019 | BindingDB | - | show |
| CHEMBL416552 | 9881905 | BindingDB | - | show |
| CHEMBL419055 | 10245325 | BindingDB | - | show |
| CHEMBL419231 | 11289209 | BindingDB | - | show |
| CHEMBL422005 | 11369471 | BindingDB | - | show |
| CHEMBL434771 | 10634938 | BindingDB | - | show |
| CHEMBL444605 | 11290186 | BindingDB | - | show |
| CHEMBL90018 | 9877881 | BindingDB | - | show |
| CHEMBL92846 | 44325327 | BindingDB | - | show |
| CHEMBL93001 | 44325367 | BindingDB | - | show |
| CHEMBL94470 | 9679790 | BindingDB | - | show |
| CHEMBL95274 | 9583359 | BindingDB | - | show |
| chlorcycloguanil | 9049 | BindingDB | - | show |
| Diaminopyritamin | 4993 | BindingDB | - | show |
| Diaminopyritamin | 4993 | DrugBank | - | show |
| Diaminopyritamin | 4993 | SuperTarget | - | show |
| DIAVERIDINE | 21453 | BindingDB | - | show |
| Ethodichlorophen | 29142 | BindingDB | - | show |
| Iem 687 | 72565 | BindingDB | - | show |
| MLS000327515 | 2764922 | BindingDB | - | show |
| NSC 267 | 5711036 | BindingDB | - | show |
| NSC211275 | 427350 | BindingDB | - | show |
| NSC211939 | 427454 | BindingDB | - | show |
| NSC274279 | 5358721 | BindingDB | - | show |
| NSC3077 (HYDROCHLORIDE SALT) | 25889 | BindingDB | - | show |
| p18 | 13926986 | BindingDB | - | show |
| Proguanil | 4923 | DrugBank | - | show |
| Proguanil | 4923 | SuperTarget | PMID 1356539 | show |
| SMR000180516 | 1473299 | BindingDB | - | show |
| Sulfamethoprim | 5578 | BindingDB | - | show |
| TCMDC-138984 | 134531 | BindingDB | - | show |
| Trp-P-2 | 5284476 | BindingDB | - | show |
| X 48 | 407233 | BindingDB | - | show |
| ZINC00128065 | 2747162 | BindingDB | - | show |
| ZINC00146421 | 732267 | BindingDB | - | show |
| ZINC04344636 | 9584159 | BindingDB | - | show |
| ZINC04710193 | 9581136 | BindingDB | - | show |
|
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| Synonyms: | | Bifunctional dihydrofolate reductase-thymidylate synthase | | DHFR-TS |
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| Similar targets: | |
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| Protein-Protein Interactions: | |
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