Target Details

Name:	Lanosterol 14-alpha demethylase
Uniprot name:	CP51A_HUMAN
Accession Numbers:	A4D1F8 B2RAI4 B4DJ55 O00770 O00772 Q16784 Q16850 Q8N1A8 Q99868
EC-Number:	1.14.13.70
Organism:	Homo sapiens Human
PDB IDs:	3I3K
KEGG Pathways:	show KEGG Pathways
Drugs:	Name PubChem ID Source References Interaction 1-(p-Azidophenyl)imidazole 178152 BindingDB - show CHEMBL127866 15934778 BindingDB - show CHEMBL305220 25142015 BindingDB - show CHEMBL339057 15934777 BindingDB - show CHEMBL447478 15934776 BindingDB - show FLUCONAZOLE 3365 DrugBank - show Intraconazole 55283 DrugBank - show Ketoconazole 456201 BindingDB - show KETOCONAZOLE 47576 DrugBank - show Ketoconazole 3823 DrugBank - show Ketoconazole 456201 DrugBank - show KETOCONAZOLE 47576 SuperCyp PMID 15611056 show Ketoconazole 3823 SuperCyp PMID 15611056 show Ketoconazole 456201 SuperCyp PMID 15611056 show Lipoglutaren 1662 SuperCyp PMID 8619637 show Miconazole 4189 DrugBank - show Sertaconazole 65863 SuperCyp - show Triaconazole 441383 DrugBank - show Triaconazole 5404 DrugBank - show Triaconazole 441383 SuperCyp PMID 2091733 show Triaconazole 5404 SuperCyp PMID 2091733 show enlarge table
Synonyms:	CYPLI Cytochrome P450 51A1 Lanosterol 14-alpha demethylase LDM P450-14DM P45014DM P450LI Sterol 14-alpha demethylase enlarge table
Similar targets:	Uniprot name % Sequence similarity % Sequence identity CP51_YEAST 54.5 36.2 CP51_CANGA 51.4 34.6 CP51_CANAL 50.3 36.3 CP51_MYCTU 47.8 29.8 CP1A1_RAT 40.6 23.1 CP1A1_HUMAN 40.5 22.2 CP4B1_RAT 40.3 23.8 CP3A7_HUMAN 40.3 24.6 CP1A1_MOUSE 40.1 21.6 CP3A2_RAT 40.1 23.1 Q2UVX5_HUMAN 39.9 22.2 Q1H8Y3_HUMAN 39.9 22.2 Q1EM53_HUMAN 39.9 22.2 Q1H8Y4_HUMAN 39.9 22.2 CP7B1_HUMAN 39.8 22.3 Q1EM52_HUMAN 39.8 21.9 CP1A2_RAT 39.8 22.8 CP1A2_MOUSE 39.8 21.9 Q1H8Y2_HUMAN 39.7 22.1 Q1H8Y5_HUMAN 39.7 22.2 Q2UVX6_HUMAN 39.7 22.2 C7DTU9_HUMAN 39.7 22.2 CP26B_HUMAN 39.6 20.9 Q53G23_HUMAN 39.6 22.1 Q1EM51_HUMAN 39.6 22.2 CP1A2_HUMAN 39.5 22.4 CP26A_HUMAN 39.4 22 Q6NWU3_HUMAN 39.4 22.5 CP4X1_HUMAN 39.4 23.9 CP24A_HUMAN 39.3 21.7 enlarge table
Protein-Protein Interactions:	Uniprot name Source LBR_HUMAN PMID 15608231 ERG24_HUMAN 2 PMIDs enlarge table

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