Target Details

Name:	5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase
Uniprot name:	CP27A_HUMAN
Accession Numbers:	A8K303 Q02318 Q6LDB4 Q86YQ6
EC-Number:	1.14.13.15
Organism:	Homo sapiens Human
PDB IDs:	1MFX
KEGG Pathways:	show KEGG Pathways
Drugs:	Name PubChem ID Source References Interaction CHEBI:653976 44445025 BindingDB - show CHEMBL1253780 46945267 BindingDB - show CHEMBL1253863 46945073 BindingDB - show CHEMBL1253864 46945450 BindingDB - show CHEMBL1253946 46945265 BindingDB - show CHEMBL363682 11523005 BindingDB - show Cholecalciferol 6221 DrugBank - show Cholecalciferol 6221 SuperCyp PMID 16158254 show Cholecalciferol 6221 SuperTarget - show CID 9982767 9982767 BindingDB - show CIPROFIBRATE 2763 SuperCyp PMID 11701475 show CYCLOSPORINE 6435893 SuperCyp PMID 11395030 show Fluormethylprednisolone 5743 SuperCyp PMID 12597773 show enlarge table
Synonyms:	5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase Cytochrome P-450C27/25 Cytochrome P450 27 Sterol 26-hydroxylase, mitochondrial Sterol 27-hydroxylase Vitamin D(3) 25-hydroxylase enlarge table
Similar targets:	Uniprot name % Sequence similarity % Sequence identity CP27B_HUMAN 54 38.5 Q548T3_HUMAN 54 38.5 CP24A_HUMAN 46.6 29.6 CP11A_HUMAN 44.3 27.4 C11B2_HUMAN 43.7 26.9 C11B1_HUMAN 43.5 27.1 CP4F2_HUMAN 40.8 23.8 CP17A_HUMAN 40.8 23 Q6GRK0_HUMAN 39.7 24.4 CP3A4_HUMAN 39.7 24.4 Q86SK3_HUMAN 39.6 24.2 CP3A2_RAT 39.3 24 THAS_RAT 39.1 22.7 CP4F8_HUMAN 39.1 21.9 Q5I2W7_HUMAN 39.1 23.7 CP3A1_RAT 39 23.4 THAS_MOUSE 38.9 22.5 THAS_HUMAN 38.8 24.3 CP46A_HUMAN 38.5 21.7 CP2A5_MOUSE 37.8 22.2 CP2A7_HUMAN 37.6 21.6 CP1A3_ONCMY 37.5 21.6 CP2S1_HUMAN 37.4 23.8 CP2B4_RABIT 37.4 23.6 CP17A_RAT 37.4 21.6 CP2J2_HUMAN 37.2 23.7 CP4F3_HUMAN 37.2 22.3 Q1H8Y5_HUMAN 37.2 23.7 CP3A7_HUMAN 37 22.9 CP2A6_HUMAN 36.9 21.2 enlarge table
Protein-Protein Interactions:	Uniprot name Source CP27A_HUMAN PMID 15608231 enlarge table

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