Target Details

Name:	Aldehyde dehydrogenase family 1 member A1
Uniprot name:	AL1A1_HUMAN
Accession Numbers:	O00768 P00352
EC-Number:	1.2.1.36
Organism:	Homo sapiens Human
PDB IDs:	-
KEGG Pathways:	show KEGG Pathways
Drugs:	Name PubChem ID Source References Interaction Alitretinoin 444795 SuperTarget - show ALITRETINOIN 449171 SuperTarget - show CHEMBL447800 10313239 BindingDB - show diethylcarbamothioylsulfanyl diethylaminomethanedithioate 3117 SuperTarget 2 PMIDs show dihydrodiphosphopyridine nucleotide 439153 DrugBank - show Isotretinoin 5538 DrugBank - show Retinol 1071 DrugBank - show Retinol 1071 SuperTarget PMID 11410291 show enlarge table
Synonyms:	Aldehyde dehydrogenase family 1 member A1 Aldehyde dehydrogenase, cytosolic ALDH-E1 ALHDII RALDH 1 RalDH1 Retinal dehydrogenase 1 enlarge table
Similar targets:	Uniprot name % Sequence similarity % Sequence identity AL1A1_SHEEP 96.8 91.6 ALDH1_ELEED 93.2 83 AL1A2_HUMAN 82.5 69 AL1A3_HUMAN 82.4 68.8 AL1A2_RAT 82.1 69.1 ALDH2_HUMAN 78.9 66 ALDH2_BOVIN 78.3 64.8 AL1B1_HUMAN 77.1 62.4 A3LNE3_PICST 64.3 49.2 Q59EJ0_HUMAN 60.2 60.2 BADH_GADCA 56.9 38.7 AL9A1_HUMAN 56.6 38.5 ABDH_ECOLI 52.7 35.2 GAPN_STRMU 48.4 31.8 P83849_THETH 47.8 31.3 Q5SYQ8_HUMAN 47.5 47.5 MMSA_HUMAN 46.2 27.3 SSDH_HUMAN 45.6 31.1 O57693_THETE 45.5 30.9 Q5SYQ9_HUMAN 45.3 45.1 AL7A1_HUMAN 43 25.7 B4YAH7_HUMAN 41.5 34.7 AL4A1_HUMAN 41.4 25.5 Q5SYQ7_HUMAN 40.5 40.5 AL3A1_RAT 39.9 25 AL3A1_HUMAN 39.2 25.1 AL3A2_HUMAN 37.3 22.4 AL3B1_HUMAN 36.9 21 AL1L1_RAT 36.6 26.4 AL1L1_HUMAN 36.1 27.3 enlarge table
Protein-Protein Interactions:	Uniprot name Source AL1A1_HUMAN PMID 12081471,16189514 ACSA_HUMAN 2 PMIDs enlarge table

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