Target Details

Name:	Aldo-keto reductase family 1 member C2
Uniprot name:	AK1C2_HUMAN
Accession Numbers:	A8K2N9 P52895 Q14133 Q5SR16 Q7M4N1 Q96A71
EC-Number:	1.-.-.- 1.1.1.213 1.3.1.20
Organism:	Homo sapiens Human
PDB IDs:	1IHI 1J96 1XJB 2HDJ 2IPJ
KEGG Pathways:	show KEGG Pathways
Drugs:	Name PubChem ID Source References Interaction 3,5-Dibromo-2-hydroxybenzoic acid 18464 BindingDB - show 3,5-DICHLOROSALICYLIC ACID 9445 BindingDB - show CHEMBL1275703 20521547 BindingDB - show CHEMBL1275704 49843991 BindingDB - show CHEMBL1275723 49844128 BindingDB - show CHEMBL1275724 52944731 BindingDB - show CHEMBL1275725 49843989 BindingDB - show CHEMBL1277646 49844129 BindingDB - show CHEMBL1277647 49844130 BindingDB - show CHEMBL1277648 49844131 BindingDB - show CHEMBL1277740 49844132 BindingDB - show CHEMBL1277741 49844133 BindingDB - show CHEMBL331146 22607959 BindingDB - show Cholsaeure 221493 SuperTarget - show Cholsaeure 6676 SuperTarget - show dihydrodiphosphopyridine nucleotide 439153 DrugBank - show Essigsaeure 176 DrugBank - show NSC109116 268734 BindingDB - show Sodium Ursodeoxycholate 31401 DrugBank - show Sodium Ursodeoxycholate 31401 SuperTarget - show Triphosphopyridine nucleotide 5886 DrugBank - show Triphosphopyridine nucleotide 5885 DrugBank - show enlarge table
Synonyms:	3-alpha-HSD3 Aldo-keto reductase family 1 member C2 Chlordecone reductase homolog HAKRD DD-2 DD/BABP DD2 Dihydrodiol dehydrogenase 2 Dihydrodiol dehydrogenase/bile acid-binding protein Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Type III 3-alpha-hydroxysteroid dehydrogenase enlarge table
Similar targets:	Uniprot name % Sequence similarity % Sequence identity AK1C1_HUMAN 98.5 97.8 AK1C3_HUMAN 92 87 AK1C4_HUMAN 90.4 81.4 PE2R_RABIT 89.2 78.9 DIDH_RAT 82.7 68.4 AK1D1_HUMAN 75.2 56.7 ALDR_HUMAN 67.5 48.3 ALDR_PIG 65.6 48.9 ALDR_BOVIN 65.3 47.4 ALD2_MOUSE 64.7 46.7 ALD2_CRIGR 64.7 47.4 ALDR_RAT 64.4 46.4 AK1A1_PIG 63.6 43 Q9GV41_9TRYP 56.3 37.8 XYL1_CANTE 54.5 37 Q9X0A2_THEMA 52.7 31.5 DKGA_CORSC 50.6 34.1 GS69_BACSU 40.4 23.8 IOLS_BACSU 37.2 22.6 SEC14_YEAST 33.5 17.9 FTSZ_THEMA 33.4 18.2 PTGR1_CAVPO 33.2 18.6 OPR1_SOLLC 32.8 17.2 HIS8_THEMA 32.7 16.1 Q99MI5_RAT 32.6 17 ARGI2_MOUSE 32.5 18.3 GLSA1_ECOLI 32.4 16.5 HNMT_MOUSE 32.4 16.5 PANC_ECOLI 32.2 17.2 O15923_TRYCR 32.1 18.6 enlarge table
Protein-Protein Interactions:	Uniprot name Source AK1C2_HUMAN PMID 11513593,11514561 enlarge table

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