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Target Details

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Name:Angiotensin-converting enzyme
Uniprot name:ACE_HUMAN
Accession Numbers:B0LPF0 P12821 P22966 Q53YX9 Q59GY8 Q7M4L4
EC-Number:3.2.1.-
3.4.15.1
Organism:Homo sapiens
Human
PDB IDs:1O86 1O8A 1UZE 1UZF 2C6F 2C6N 2IUL 2IUX 2OC2 3BKK 3BKL
KEGG Pathways:show KEGG Pathways
Drugs:
NamePubChem IDSourceReferencesInteraction
()-oxazepam hemisuccinate sodium salt25077620BindingDB-show
()-oxazepam hemisuccinate sodium salt44346192BindingDB-show
(2S)-1-[(2S)-2-(diphenoxyphosphorylamino)propanoyl]pyrrolidine-2-carboxyli3035726BindingDB-show
1,3,5,6-Tetrahydroxyxanthen-9-one5479774BindingDB-show
1-(3-Mercapto-1-oxopropyl)-L-proline99978BindingDB-show
1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID447055DrugBank-show
1zdp4369380BindingDB-show
2-(4-Morpholinyl)-4H-1-benzopyran-4-one131255BindingDB-show
2-[(2-benzyl-5-methyl-3-sulfanyl-hexanoyl)amino]propanoic Acid10381547BindingDB-show
2-[(FORMYL-HYDROXY-AMINO)-METHYL]-HEXANOIC ACID (1-DIMETHYLCARBAMOYL-2,2-DIMETHYL-PROPYL)-AMIDE159596BindingDB-show
3-(benzenesulfonyl)-N-hydroxy-heptanamide9838786BindingDB-show
3-(Mercaptomethyl)-3,4,5,6-tetrahydro-2-oxo-1H-1-benzazocine-1-acetic acid145994BindingDB-show
3-(Mercaptomethyl-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid)145993BindingDB-show
3-Isoquinolinecarboxylic acid, 2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-5005BindingDB-show
32223222BindingDB-show
4430500544305005BindingDB-show
4430714044307140BindingDB-show
5-Bmopp134166BindingDB-show
AC1L73MC354080BindingDB-show
AC1L7HPG335542BindingDB-show
AC1L9AR0441208BindingDB-show
AC1L9MKX448982BindingDB-show
AC1LELPO688267BindingDB-show
AC1MD03C2828746BindingDB-show
AC1NBW1Q4474936BindingDB-show
AC1O3UZC6338603BindingDB-show
AC1O42346321211BindingDB-show
AC1O426Y6321429BindingDB-show
AC1O44IQ6324648BindingDB-show
AC1ODT5E7020447BindingDB-show
AC1OEMTM7059511BindingDB-show
AC1OLR0Q7408255BindingDB-show
Actinonine443600BindingDB-show
Benalapril5388961PROMISCUOUSPMID 9495881show
benazepril hydrochloride5362124BindingDB-show
benazepril hydrochloride5362124DrugBank-show
benazepril hydrochloride5362124SuperTargetPMID 016364833show
BPGP130842BindingDB-show
BRN 55448902828749BindingDB-show
CAPTOPRIL AND HYDROCHLOROTHIAZIDE44093BindingDB-show
CAPTOPRIL AND HYDROCHLOROTHIAZIDE44093DrugBank-show
CAPTOPRIL AND HYDROCHLOROTHIAZIDE44093SuperTarget2 PMIDsshow
Cgs 13934134126BindingDB-show
CHEBI:10694512877547BindingDB-show
CHEBI:11675944288610BindingDB-show
CHEBI:11675944307141BindingDB-show
CHEBI:116759443379BindingDB-show
CHEBI:12559144274002BindingDB-show
CHEBI:24862344324747BindingDB-show
CHEBI:29432544344790BindingDB-show
CHEBI:31256044351723BindingDB-show
CHEBI:31318144351940BindingDB-show
CHEBI:34737544365477BindingDB-show
CHEBI:35444544368335BindingDB-show
CHEBI:55059344561933BindingDB-show
CHEBI:64431244284877BindingDB-show
CHEBI:64884644385866BindingDB-show
CHEBI:65078644284653BindingDB-show
CHEBI:65080344284875BindingDB-show
CHEMBL10004444329454BindingDB-show
CHEMBL10006313456399BindingDB-show
CHEMBL10041313456344BindingDB-show
CHEMBL10058613456346BindingDB-show
CHEMBL10082613456404BindingDB-show
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CHEMBL10136013456366BindingDB-show
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CID 1007263010321691BindingDB-show
CID 1040984510364792BindingDB-show
CID 1041161610072629BindingDB-show
CID 1045466810093438BindingDB-show
CID 1047630510046773BindingDB-show
CID 1066453810664538BindingDB-show
CID 1171872211718722BindingDB-show
CID 99067209906720BindingDB-show
CID 998217311442784BindingDB-show
CID 998217311328897BindingDB-show
CID 998217311259963BindingDB-show
CID 99825849982584BindingDB-show
CILAZAPRIL MONOHYDRATE56329SuperTargetPMID 1838916show
Desmethoxyreserpine8550DrugBank-show
Desmethoxyreserpine8550SuperTarget-show
enalapril5388962BindingDB-show
Enalapril acid3691183BindingDB-show
Enalaprilat5362032DrugBank-show
Enalaprilate5462501BindingDB-show
Essigsaeure176DrugBank-show
EU 4865132472BindingDB-show
EU 4881146389BindingDB-show
Fosinopril55891DrugBank-show
Fosinopril55891SuperTarget2 PMIDsshow
Fosinoprilat62956BindingDB-show
Grassystatin A44255320BindingDB-show
Imidapril5464343BindingDB-show
Imidapril5464343SuperTargetPMID 14594552show
Imidaprilat5464344BindingDB-show
Indolapril5525BindingDB-show
Ketoace156271BindingDB-show
L-Alanyl-L-proline83525BindingDB-show
LIBENZAPRIL71320BindingDB-show
Lisinopril5362119BindingDB-show
Lisinopril5362119DrugBank-show
Lisinopril5362119SuperTarget-show
Lisinopril dihydrate5362118BindingDB-show
Losartan3961BindingDB-show
Lostapres5362129BindingDB-show
Lostapres5362129DrugBank-show
Lostapres5362129SuperTarget2 PMIDsshow
LS-1932727408195BindingDB-show
Mercaptopropionylglycine5483BindingDB-show
Methyl Trimethoxycinnamoylreserpate32681DrugBank-show
Methyl Trimethoxycinnamoylreserpate32681SuperTarget-show
MMOPA133560BindingDB-show
Moexipril hydrochloride91270BindingDB-show
Moexipril hydrochloride91270DrugBank-show
Moexipril hydrochloride91270SuperTarget2 PMIDsshow
N-acetyl-alpha-D-glucosaminides82313DrugBank-show
Norathyriol5281656BindingDB-show
NSC301507327260BindingDB-show
NSC604536494324BindingDB-show
Omapatrilat656629BindingDB-show
Perindopril107807DrugBank-show
PERINDOPRIL60184DrugBank-show
Perindopril107807SuperTargetPMID 8800599show
PERINDOPRIL60184SuperTargetPMID 8800599show
Phosphinic Peptide Inhibitor, 28 FII24776225BindingDB-show
Phosphinic Peptide Inhibitor, 34 FII24776231BindingDB-show
Phosphinic Peptide Inhibitor, 40 FII24776234BindingDB-show
Phosphinic Peptide Inhibitor, 41 FII24776235BindingDB-show
Pivalopril156874BindingDB-show
Ppp-ala-pro126655BindingDB-show
Quinaprilum54892DrugBank-show
Quinaprilum54892SuperTarget2 PMIDsshow
SMR0001352092834684BindingDB-show
Spirapril hydrochloride5311447DrugBank-show
Spirapril hydrochloride5311447SuperTargetPMID 10052652show
SPIRAPRILAT3033702BindingDB-show
SQ 28603123742BindingDB-show
ST047481555078BindingDB-show
ST0821102252167BindingDB-show
Temocaprilat443151BindingDB-show
Thiorphan3132BindingDB-show
Trandolapril5484727DrugBank-show
Trandolapril5484727SuperTarget2 PMIDsshow
Trandolaprilate128549BindingDB-show
Val-trp168182BindingDB-show
Zofenopril92400BindingDB-show
Zofenoprilat3034048BindingDB-show
[(2s)-2-({3-[hydroxyl(2-Phenyl-(1r)-1-{[(Benzyloxy)[(2s)-2-({3-[hydroxyl(211556698BindingDB-show
Synonyms:
ACE
Angiotensin-converting enzyme
CD143
Dipeptidyl carboxypeptidase I
Kininase II
Similar targets:
Uniprot name% Sequence similarity% Sequence identity
PUTA_ECOLI3018.1
O77690_BOVIN29.917.7
CA2D2_HUMAN29.517.9
PK3CG_PIG29.317.2
PK3CB_HUMAN29.316.6
METH_ECOLI29.217.5
GUC2C_CAVPO29.216.6
CY41_TRYBB29.218
MDR3_HUMAN29.116.7
Q4G0Q4_HUMAN28.916.7
ACE2_HUMAN28.719.4
PK3CB_MOUSE28.617.4
DGKD_HUMAN28.616.6
GUC2C_PIG28.116.1
NIFJ_ECOLI27.917.1
ACE_DROME27.620
P94692_DESAF27.616.5
TRI_THEAC27.315.9
PLCL1_HUMAN27.317
Q59EW6_HUMAN27.316.2
NOS1_MOUSE27.217.1
NOS2_CHICK27.115.7
ITAL_HUMAN2716.3
MRC1_MOUSE26.916.2
KLOT_HUMAN26.917.1
JAK3_RAT26.716.4
DPOL_BPR6926.714.3
Q59F93_HUMAN26.615.4
RPOB_ECOLI26.415.3
DUOX1_RAT26.416.1
Protein-Protein Interactions:
No data available